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NCT04520373 · ClinicalTrials.gov registry record · Phase 2
Autologous Adipose Derived Mesenchymal Stem Cells for Spinal Cord Injury Patients
A Phase 2 study of Spinal Cord Injuries and Paralysis, sponsored by Mayo Clinic.
- Active
- Registry status
- Phase 2
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT04520373: Active Phase 2 study of Spinal Cord Injuries and Paralysis, sponsored by Mayo Clinic.
NCT04520373 is a Phase 2 study of Spinal Cord Injuries and Paralysis that is active but no longer recruiting, run by Mayo Clinic. The registered enrollment target is 40 participants, below the 61-participant average among 202 other Spinal Cord Injuries trials with a reported enrollment target (34% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04520373, a Phase 2 study of Spinal Cord Injuries and Paralysis, is active but no longer recruiting, sponsored by Mayo Clinic.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this research study is to investigate the safety and potential therapeutic effects of autologous, culture-expanded, adipose derived mesenchymal stem cell intrathecal injections in the treatment of spinal cord injury.
Primary Outcome
The ASIA Impairment Scale describes a person's functional impairment (both motor and sensory) as a result of their spinal cord injury. The scale has 5 levels, ranging from A (complete) to E (normal).
Conditions Studied
Interventions
- OTHER Best Medical Management: Occupational and Physical Therapy
- BIOLOGICAL Autologous, Adipose Derived Mesenchymal Stem Cells
Study Locations (1)
Minnesota
- Mayo Clinic in Rochester - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2020-06-25 |
| Est. Completion | 2026-07 |
| Phase | Phase 2 |
What the registry record for NCT04520373 still lists
NCT04520373 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 61-participant average among 202 other Spinal Cord Injuries trials with a reported enrollment target (34% lower).
The record links to 2 conditions, with Spinal Cord Injuries appearing as the primary indexed condition, and to 2 interventions - of which Best Medical Management: Occupational and Physical Therapy is the first listed.
NCT04520373 reports a single indexed study location in Minnesota.
Frequently Asked Questions
What is clinical trial NCT04520373 about?
NCT04520373 is a clinical study titled "Autologous Adipose Derived Mesenchymal Stem Cells for Spinal Cord Injury Patients". The purpose of this research study is to investigate the safety and potential therapeutic effects of autologous, culture-expanded, adipose derived mesenchymal stem cell intrathecal injections in the treatment of spinal cord injury.
What is the current status of trial NCT04520373?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 2020-06-25. Estimated completion is 2026-07.
What conditions does trial NCT04520373 study?
This clinical trial studies the following conditions: Spinal Cord Injuries, Paralysis.
What interventions are being tested in trial NCT04520373?
The interventions under investigation include: Best Medical Management: Occupational and Physical Therapy (OTHER), Autologous, Adipose Derived Mesenchymal Stem Cells (BIOLOGICAL).
Who is sponsoring clinical trial NCT04520373?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04520373 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Spinal Cord Injuries
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04520373's enrollment target sits among peer trials
40 72nd of 202 higher than 124 of 202 other Spinal Cord Injuries trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Spinal Cord Injuries trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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