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NCT04041063 · ClinicalTrials.gov registry record · Phase 2

Rehabilitation and Cortical Remodeling After Surgical Intervention for Spinal Cord Injury

A Phase 2 study of Spinal Cord Injuries and Tetraplegia, sponsored by Burke Medical Research Institute.

Active
Registry status
Phase 2
Development phase
6
Enrollment target
1
Study location

NCT04041063: Active Phase 2 study of Spinal Cord Injuries and Tetraplegia, sponsored by Burke Medical Research Institute.

NCT04041063 is a Phase 2 study of Spinal Cord Injuries and Tetraplegia that is active but no longer recruiting, run by Burke Medical Research Institute. The registered enrollment target is 6 participants, below the 62-participant average among 202 other Spinal Cord Injuries trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04041063, a Phase 2 study of Spinal Cord Injuries and Tetraplegia, is active but no longer recruiting, sponsored by Burke Medical Research Institute.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
6 participants
Enrollment target
1
Study location

Study Summary

The aim of this study is to determine the effects of rehabilitation on dexterous hand movements and cortical motor map changes in tetraplegic patients following nerve transfer surgery. The working hypothesis is that robot-assisted, intensive rehabilitation will support the return of hand and arm function and strengthen the cortical representations of targeted muscles. The investigators will assess this through TMS mapping and clinical measures of hand and arm function.

Primary Outcome

The Box and Blocks test measures how many blocks a person can grasp and transfer in one minute. A higher score is associated with better hand function.

Conditions Studied

Spinal Cord Injuries Tetraplegia Cervical Spinal Cord Injury

Interventions

  • DEVICE Upper limb robotic training
  • PROCEDURE Nerve transfer surgery

Study Locations (1)

New York

  • Burke Neurological Institute - White Plains

Trial Details

FieldValue
Enrollment Target 6 participants
Start Date 2019-07-26
Est. Completion 2026-12-31
Phase Phase 2
Burke Medical Research Institute

11 total trials

What the registry record for NCT04041063 still lists

NCT04041063 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 62-participant average among 202 other Spinal Cord Injuries trials with a reported enrollment target (90% lower).

The record links to 3 conditions, with Spinal Cord Injuries appearing as the primary indexed condition, and to 2 interventions - of which Upper limb robotic training is the first listed.

NCT04041063 reports a single indexed study location in New York.

Frequently Asked Questions

What is clinical trial NCT04041063 about?

NCT04041063 is a clinical study titled "Rehabilitation and Cortical Remodeling After Surgical Intervention for Spinal Cord Injury". The aim of this study is to determine the effects of rehabilitation on dexterous hand movements and cortical motor map changes in tetraplegic patients following nerve transfer surgery. The working hypothesis is that robot-assisted, intensive rehabilitation will support the return of hand and arm fun...

What is the current status of trial NCT04041063?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 6 participants. The study started on 2019-07-26. Estimated completion is 2026-12-31.

What conditions does trial NCT04041063 study?

This clinical trial studies the following conditions: Spinal Cord Injuries, Tetraplegia, Cervical Spinal Cord Injury.

What interventions are being tested in trial NCT04041063?

The interventions under investigation include: Upper limb robotic training (DEVICE), Nerve transfer surgery (PROCEDURE).

Who is sponsoring clinical trial NCT04041063?

This trial is sponsored by Burke Medical Research Institute, which has 11 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04041063 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Spinal Cord Injuries

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04041063's enrollment target sits among peer trials

6 183rd of 202 higher than 14 of 202 other Spinal Cord Injuries trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Spinal Cord Injuries trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Related registry views

Source: ClinicalTrials.gov NCT04041063, the US trial registry maintained by the National Library of Medicine. NCT04041063 (small enrollment · single site footprint · active not recruiting) retrieved and formatted by PlainTrial, see methodology.