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NCT05589402 · ClinicalTrials.gov registry record · Phase 1
Temporary Inactivation of Strong Muscle Sensation to Improve Rehabilitation Interventions in SCI
A Phase 1 study of Stroke and Spinal Cord Injuries, sponsored by University of Texas Rio Grande Valley.
- Active
- Registry status
- Phase 1
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT05589402: Active Phase 1 study of Stroke and Spinal Cord Injuries, sponsored by University of Texas Rio Grande Valley.
NCT05589402 is a Phase 1 study of Stroke and Spinal Cord Injuries that is active but no longer recruiting, run by University of Texas Rio Grande Valley. The registered enrollment target is 30 participants, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05589402, a Phase 1 study of Stroke and Spinal Cord Injuries, is active but no longer recruiting, sponsored by University of Texas Rio Grande Valley.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
The investigators are conducting a research study to try to improve rehabilitation interventions for individuals with spinal cord injury (SCI). In this study, the aim is to determine if temporarily numbing non-paralyzed arm muscles with an over-the-counter numbing cream while exercising paralyzed muscles, can improve the strength, function, and sensation of paralyzed muscles after a spinal cord injury.
Primary Outcome
The investigators will use an electrical stimulator to send an electrical signal to a target muscle to initiate contraction, and an Electromyography (EMG) will be used to record the changes in target muscle response from baseline, pre-test, and post-test. An electronic nerve stimulator will output a pulse ranging from 0 mV to 2 mV for an appropriate maximum muscle contraction to occur, and an Electromyography (EMG in root mean square) will capture the muscle's contraction via surface electrodes
Conditions Studied
Interventions
- DRUG Lidocaine Cream 5%
- OTHER Rehabilitation Movement Training
Study Locations (1)
Texas
- University of Texas Rio Grande Valley - Harlingen
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2019-06-04 |
| Est. Completion | 2026-06-04 |
| Phase | Phase 1 |
What the registry record for NCT05589402 still lists
NCT05589402 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (100% lower).
The record links to 3 conditions, with Stroke appearing as the primary indexed condition, and to 2 interventions - of which Lidocaine Cream 5% is the first listed.
NCT05589402 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT05589402 about?
NCT05589402 is a clinical study titled "Temporary Inactivation of Strong Muscle Sensation to Improve Rehabilitation Interventions in SCI". The investigators are conducting a research study to try to improve rehabilitation interventions for individuals with spinal cord injury (SCI). In this study, the aim is to determine if temporarily numbing non-paralyzed arm muscles with an over-the-counter numbing cream while exercising paralyzed mu...
What is the current status of trial NCT05589402?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2019-06-04. Estimated completion is 2026-06-04.
What conditions does trial NCT05589402 study?
This clinical trial studies the following conditions: Stroke, Spinal Cord Injuries, Spine Disease.
What interventions are being tested in trial NCT05589402?
The interventions under investigation include: Lidocaine Cream 5% (DRUG), Rehabilitation Movement Training (OTHER).
Who is sponsoring clinical trial NCT05589402?
This trial is sponsored by University of Texas Rio Grande Valley, which has 7 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05589402 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Stroke
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05589402's enrollment target sits among peer trials
30 301st of 454 higher than 137 of 454 other Stroke trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Stroke trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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