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NCT05321017 · ClinicalTrials.gov registry record · NA
Wrist Extensor MEP Up-conditioning for Individuals With Incomplete Spinal Cord Injury
A NA study of Spinal Cord Injuries and Quadriplegia, sponsored by Medical University of South Carolina.
- Recruiting
- Registry status
- NA
- Development phase
- 5
- Enrollment target
- 1
- Study location
NCT05321017: Recruiting NA study of Spinal Cord Injuries and Quadriplegia, sponsored by Medical University of South Carolina.
NCT05321017 is a NA study of Spinal Cord Injuries and Quadriplegia that is actively recruiting participants, run by Medical University of South Carolina. The registered enrollment target is 5 participants, below the 62-participant average among 202 other Spinal Cord Injuries trials with a reported enrollment target (92% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05321017, a NA study of Spinal Cord Injuries and Quadriplegia, is actively recruiting participants, sponsored by Medical University of South Carolina.
- RECRUITING
- Registry status
- NA
- Development phase
- 5 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to examine the relationship between common clinical assessments and measurements of the function of brain-spinal cord-muscle connections, and to examine the effects of training a brain-spinal cord-muscle response in individuals with incomplete spinal cord injury. A transcranial magnetic stimulator (TMS) is used for examining brain-to-muscle pathways. This stimulator produces a magnetic field for a very short period of time and indirectly stimulates brain cells with little or no discomfort. The target muscle is the wrist extensor (extensor carpi radialis) muscle that bends the wrist back. It is hypothesized that training the wrist extensor muscle response to transcranial magnetic stimulation will increase the strength of the brain-to-muscle pathway, which will improve the ability to move the arm. It is hoped that the results of this training study will help in developing therapy strategies for individuals, promoting better understanding of clinical assessments, and understanding treatments that aim to improve function recovery in people with spinal cord injury (SCI). This study requires 30 visits, and each visit will last approximately 1.5 hours.
Primary Outcome
An increased average MEP size (mV) would indicate increased excitability/strength of the brain-spinal cord-muscle pathway
Conditions Studied
Interventions
- BEHAVIORAL MEP Operant Up-conditioning of the Wrist Extensor
Study Locations (1)
South Carolina
- Medical University of South Carolina - Charleston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5 participants |
| Start Date | 2021-10-12 |
| Est. Completion | 2026-06-30 |
| Phase | NA |
What NCT05321017 shows while recruiting
NCT05321017 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 5 participants, a relatively small participant target, below the 62-participant average among 202 other Spinal Cord Injuries trials with a reported enrollment target (92% lower).
The record links to 2 conditions, with Spinal Cord Injuries appearing as the primary indexed condition, and to 1 intervention - of which MEP Operant Up-conditioning of the Wrist Extensor is the first listed.
NCT05321017 reports a single indexed study location in South Carolina.
Frequently Asked Questions
What is clinical trial NCT05321017 about?
NCT05321017 is a clinical study titled "Wrist Extensor MEP Up-conditioning for Individuals With Incomplete Spinal Cord Injury". The purpose of this study is to examine the relationship between common clinical assessments and measurements of the function of brain-spinal cord-muscle connections, and to examine the effects of training a brain-spinal cord-muscle response in individuals with incomplete spinal cord injury. A trans...
What is the current status of trial NCT05321017?
This trial is currently recruiting. It is a NA study. The enrollment target is 5 participants. The study started on 2021-10-12. Estimated completion is 2026-06-30.
What conditions does trial NCT05321017 study?
This clinical trial studies the following conditions: Spinal Cord Injuries, Quadriplegia.
What interventions are being tested in trial NCT05321017?
The interventions under investigation include: MEP Operant Up-conditioning of the Wrist Extensor (BEHAVIORAL).
Who is sponsoring clinical trial NCT05321017?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05321017 being conducted?
This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Spinal Cord Injuries
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05321017's enrollment target sits among peer trials
5 190th of 202 higher than 8 of 202 other Spinal Cord Injuries trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Spinal Cord Injuries trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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