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NCT04520178 · ClinicalTrials.gov registry record · Phase 2

Effects of 5HTP on the Injured Human Spinal Cord

A Phase 2 study of Spinal Cord Injuries, sponsored by University of Alberta.

Recruiting
Registry status
Phase 2
Development phase
30
Enrollment target
2
Study locations

NCT04520178 is a Phase 2 study of Spinal Cord Injuries that is actively recruiting participants, run by University of Alberta. The registered enrollment target is 30 participants, below the 61-participant average among 202 other Spinal Cord Injuries trials with a reported enrollment target (51% lower). The trial reports 2 study locations across 2 states.

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The verdict

NCT04520178, a Phase 2 study of Spinal Cord Injuries, is actively recruiting participants, sponsored by University of Alberta.

RECRUITING
Registry status
Phase 2
Development phase
30 participants
Enrollment target
2
Study locations

Study Summary

This study will assess how the serotonin precursor, 5-HTP, alter nervous system excitability and motor function in individuals with spinal cord injuries of differing chronicity and severity. Participants will visit the lab on 4 separate occasions where they will be administered four different drugs in a randomized, double-blinded, placebo-controlled crossover design.

Conditions Studied

Spinal Cord Injuries

Interventions

  • DRUG Placebo
  • DRUG 5-Hydroxytryptophan
  • DRUG 5-Hydroxytryptophan 100 MG
  • DRUG Carbidopa

Study Locations (2)

Kentucky

  • University of Louisville - Louisville

Alberta

  • University of Alberta - Edmonton

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2020-07-01
Est. Completion 2026-12-30
Phase Phase 2

Sponsor

University of Alberta

19 total trials

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What the Registry Record Tells You About NCT04520178

The ClinicalTrials.gov registry entry for NCT04520178 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 61-participant average among 202 other Spinal Cord Injuries trials with a reported enrollment target (51% lower). The listed sponsor is University of Alberta, which has 19 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Spinal Cord Injuries appearing as the primary indexed condition, and to 4 interventions - of which Placebo is the first listed.

NCT04520178 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Kentucky, Alberta.

Frequently Asked Questions

What is clinical trial NCT04520178 about?

NCT04520178 is a clinical study titled "Effects of 5HTP on the Injured Human Spinal Cord". This study will assess how the serotonin precursor, 5-HTP, alter nervous system excitability and motor function in individuals with spinal cord injuries of differing chronicity and severity. Participants will visit the lab on 4 separate occasions where they will be administered four different drugs ...

What is the current status of trial NCT04520178?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 30 participants. The study started on 2020-07-01. Estimated completion is 2026-12-30.

What conditions does trial NCT04520178 study?

This clinical trial studies the following conditions: Spinal Cord Injuries.

What interventions are being tested in trial NCT04520178?

The interventions under investigation include: Placebo (DRUG), 5-Hydroxytryptophan (DRUG), 5-Hydroxytryptophan 100 MG (DRUG), Carbidopa (DRUG).

Who is sponsoring clinical trial NCT04520178?

This trial is sponsored by University of Alberta, which has 19 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04520178 being conducted?

This trial has 2 study locations across Kentucky, Alberta. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.