Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT06313515 · ClinicalTrials.gov registry record · NA

Transcutaneous Spinal Cord Stimulation Combined With Arm Bike for Cardiovascular Recovery in SCI

A NA study of Spinal Cord Injuries, sponsored by University of Washington.

Recruiting
Registry status
NA
Development phase
16
Enrollment target
1
Study location

NCT06313515: Recruiting NA study of Spinal Cord Injuries, sponsored by University of Washington.

NCT06313515 is a NA study of Spinal Cord Injuries that is actively recruiting participants, run by University of Washington. The registered enrollment target is 16 participants, below the 62-participant average among 202 other Spinal Cord Injuries trials with a reported enrollment target (74% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT06313515, a NA study of Spinal Cord Injuries, is actively recruiting participants, sponsored by University of Washington.

RECRUITING
Registry status
NA
Development phase
16 participants
Enrollment target
1
Study location

Study Summary

Spinal cord injury (SCI) can make it hard for the body to self-regulate some of its automatic functions like blood pressure, breathing, and heart rate. This can also make it hard for those living with SCI to exercise or complete their usual daily activities. The goal of this randomized trial is to test combinatory therapy of moderate arm-crank exercise paired with non-invasive transcutaneous spinal cord stimulation (tSCS) for cardiovascular recovery in adults aged 21-65 following chronic motor-complete spinal cord injury (SCI) at or above the thoracic sixth spinal segment (≥T6). The main questions the study aims to answer are: * Conduct tSCS mapping to determine the most effective location and stimulation intensity for BP control in individuals with motor-complete SCI ≥ T6. * Evaluate the effects 8 weeks of targeted tSCS paired with arm-crank exercise compared to sham stimulation with exercise on improving cardiovascular function in individuals with motor-complete SCI ≥T6. * Evaluate the dosage-response of 8 weeks vs. 16 weeks of targeted tSCS paired with arm-crank exercise on cardiovascular function in individuals with motor-complete SCI ≥T6. * Explore the mechanisms involved in cardiovascular recovery with long-term tSCS paired with arm-crank exercise. Participants will: * Receive either transcutaneous spinal cord stimulation or "sham" spinal cord stimulation while exercising on an arm-crank bicycle in the first 8 weeks. * Come in for approximately 60 visits over a 6-month period. This includes 2, 8-week periods where the investigators will ask participants to come in 3x per week for spinal cord stimulation and exercise. * During assessment visits the researchers will perform a variety of exams including a neurologic, cardiovascular, pulmonary, physical, and autonomic exam, and will ask questions about quality of life and functioning. Researchers will compare those who receive tSCS and do moderate arm-crank exercise to those who receive a sham stimulation and

Primary Outcome

Continuous beat-by-beat BP will be measured using a finger photoplethysmography.

Conditions Studied

Spinal Cord Injuries

Interventions

  • OTHER Sham Stimulation
  • DEVICE Transcutaneous Spinal Cord Stimulation
  • BEHAVIORAL Arm-crank bike exercise

Study Locations (1)

Washington

  • University of Washington - Seattle

Trial Details

FieldValue
Enrollment Target 16 participants
Start Date 2024-04-01
Est. Completion 2027-02-01
Phase NA
University of Washington

1,048 total trials

What NCT06313515 shows while recruiting

NCT06313515 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 62-participant average among 202 other Spinal Cord Injuries trials with a reported enrollment target (74% lower).

The record links to 1 condition, with Spinal Cord Injuries appearing as the primary indexed condition, and to 3 interventions - of which Sham Stimulation is the first listed.

NCT06313515 reports a single indexed study location in Washington.

Frequently Asked Questions

What is clinical trial NCT06313515 about?

NCT06313515 is a clinical study titled "Transcutaneous Spinal Cord Stimulation Combined With Arm Bike for Cardiovascular Recovery in SCI". Spinal cord injury (SCI) can make it hard for the body to self-regulate some of its automatic functions like blood pressure, breathing, and heart rate. This can also make it hard for those living with SCI to exercise or complete their usual daily activities. The goal of this randomized trial is to t...

What is the current status of trial NCT06313515?

This trial is currently recruiting. It is a NA study. The enrollment target is 16 participants. The study started on 2024-04-01. Estimated completion is 2027-02-01.

What conditions does trial NCT06313515 study?

This clinical trial studies the following conditions: Spinal Cord Injuries.

What interventions are being tested in trial NCT06313515?

The interventions under investigation include: Sham Stimulation (OTHER), Transcutaneous Spinal Cord Stimulation (DEVICE), Arm-crank bike exercise (BEHAVIORAL).

Who is sponsoring clinical trial NCT06313515?

This trial is sponsored by University of Washington, which has 1,048 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06313515 being conducted?

This trial has 1 study location across Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Spinal Cord Injuries

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06313515's enrollment target sits among peer trials

16 145th of 202 higher than 53 of 202 other Spinal Cord Injuries trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Spinal Cord Injuries trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02422641 · 16 participants · Phase 2

    Prospective Evaluation Of High-Dose Systemic Methotrexate In Patients With Breast Cancer And Leptomeningeal Metastasis

  • NCT02851758 · 16 participants · NA

    Transplantation of Autologously Derived Mitochondria Following Ischemia

  • NCT03291028 · 16 participants

    Analysis of Primary and Metastatic Tumors in Patients With Renal Cell Carcinoma and Urothelial Carcinoma

  • NCT03425526 · 16 participants · Phase 1

    Donor T Cell Therapy in Treating Immunocompromised Patients With Adenovirus-Related Disease

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT06358040 · started 2026-10 · NA

    Opioid Dispenser for Microdiscectomy/Laminectomy

More recruiting context for NCT06313515

Source: ClinicalTrials.gov NCT06313515, the US trial registry maintained by the National Library of Medicine. NCT06313515 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.