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NCT04144972 · ClinicalTrials.gov registry record · NA
Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain
A NA study of Spinal Cord Injuries and Pain, Postoperative, sponsored by University of California, San Francisco.
- Recruiting
- Registry status
- NA
- Development phase
- 12
- Enrollment target
- 1
- Study location
NCT04144972: Recruiting NA study of Spinal Cord Injuries and Pain, Postoperative, sponsored by University of California, San Francisco.
NCT04144972 is a NA study of Spinal Cord Injuries and Pain, Postoperative that is actively recruiting participants, run by University of California, San Francisco. The registered enrollment target is 12 participants, below the 62-participant average among 202 other Spinal Cord Injuries trials with a reported enrollment target (81% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04144972, a NA study of Spinal Cord Injuries and Pain, Postoperative, is actively recruiting participants, sponsored by University of California, San Francisco.
- RECRUITING
- Registry status
- NA
- Development phase
- 12 participants
- Enrollment target
- 1
- Study location
Study Summary
Chronic pain affects 1 in 4 US adults, and many cases are resistant to almost any treatment. Deep brain stimulation (DBS) holds promise as a new option for patients suffering from treatment-resistant chronic pain, but traditional approaches target only brain regions involved in one aspect of the pain experience and provide continuous 24/7 brain stimulation which may lose effect over time. By developing new technology that targets multiple, complimentary brain regions in an adaptive fashion, the investigators will test a new therapy for chronic pain that has potential for better, more enduring analgesia.
Primary Outcome
Identifying biomarkers in machine learning models that exceed chance and stimulation sites that provide clinically meaningful reductions in chronic pain during a temporary brain stimulation and recording period in hospital
Conditions Studied
Interventions
- DEVICE Medtronic Summit RC+S or Percept RC
Study Locations (1)
California
- University of California, San Francisco - San Francisco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2019-10-24 |
| Est. Completion | 2030-10-24 |
| Phase | NA |
What NCT04144972 shows while recruiting
NCT04144972 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 62-participant average among 202 other Spinal Cord Injuries trials with a reported enrollment target (81% lower).
The record links to 9 conditions, with Spinal Cord Injuries appearing as the primary indexed condition, and to 1 intervention - of which Medtronic Summit RC+S or Percept RC is the first listed.
NCT04144972 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT04144972 about?
NCT04144972 is a clinical study titled "Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain". Chronic pain affects 1 in 4 US adults, and many cases are resistant to almost any treatment. Deep brain stimulation (DBS) holds promise as a new option for patients suffering from treatment-resistant chronic pain, but traditional approaches target only brain regions involved in one aspect of the pai...
What is the current status of trial NCT04144972?
This trial is currently recruiting. It is a NA study. The enrollment target is 12 participants. The study started on 2019-10-24. Estimated completion is 2030-10-24.
What conditions does trial NCT04144972 study?
This clinical trial studies the following conditions: Spinal Cord Injuries, Pain, Postoperative, Complex Regional Pain Syndromes, Nerve Injury, Post Herpetic Neuralgia.
What interventions are being tested in trial NCT04144972?
The interventions under investigation include: Medtronic Summit RC+S or Percept RC (DEVICE).
Who is sponsoring clinical trial NCT04144972?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04144972 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Spinal Cord Injuries
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04144972's enrollment target sits among peer trials
12 165th of 202 higher than 30 of 202 other Spinal Cord Injuries trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Spinal Cord Injuries trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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