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NCT04263285 · ClinicalTrials.gov registry record · NA
Treatment of Depression Post-SCI
A NA study of Depression and Spinal Cord Injuries, sponsored by Medical University of South Carolina.
- Recruiting
- Registry status
- NA
- Development phase
- 14
- Enrollment target
- 1
- Study location
NCT04263285: Recruiting NA study of Depression and Spinal Cord Injuries, sponsored by Medical University of South Carolina.
NCT04263285 is a NA study of Depression and Spinal Cord Injuries that is actively recruiting participants, run by Medical University of South Carolina. The registered enrollment target is 14 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04263285, a NA study of Depression and Spinal Cord Injuries, is actively recruiting participants, sponsored by Medical University of South Carolina.
- RECRUITING
- Registry status
- NA
- Development phase
- 14 participants
- Enrollment target
- 1
- Study location
Study Summary
Depression is more common after a spinal cord injury (SCI) than in the general population. Unfortunately, it is unknown how depression is typically treated in individuals with SCI or if commonly used treatment methods are effective. This study will investigate the safety and impact of a novel method for treating depression called repetitive transcranial magnetic stimulation (rTMS). rTMS is a type of non-invasive brain stimulation. Fourteen individuals with a cervical or thoracic level SCI and depression will complete an approved treatment plan using rTMS. Participants will be treated using rTMS five days a week for four weeks. After four weeks of treatment, the study team will review the safety of rTMS and assess changes in depressive symptoms. If the results are positive, larger studies can be designed to develop better treatment options for individuals with SCI and depression.
Primary Outcome
Report of adverse and serious adverse events in all participants.
Conditions Studied
Interventions
- DEVICE rTMS
Study Locations (1)
South Carolina
- Medical University of South Carolina - Charleston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 14 participants |
| Start Date | 2026-10 |
| Est. Completion | 2029-09 |
| Phase | NA |
What NCT04263285 shows while recruiting
NCT04263285 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 14 participants, a relatively small participant target, below the 786-participant average among 679 other Depression trials with a reported enrollment target (98% lower).
The record links to 2 conditions, with Depression appearing as the primary indexed condition, and to 1 intervention - of which rTMS is the first listed.
NCT04263285 reports a single indexed study location in South Carolina.
Frequently Asked Questions
What is clinical trial NCT04263285 about?
NCT04263285 is a clinical study titled "Treatment of Depression Post-SCI". Depression is more common after a spinal cord injury (SCI) than in the general population. Unfortunately, it is unknown how depression is typically treated in individuals with SCI or if commonly used treatment methods are effective. This study will investigate the safety and impact of a novel method...
What is the current status of trial NCT04263285?
This trial is currently recruiting. It is a NA study. The enrollment target is 14 participants. The study started on 2026-10. Estimated completion is 2029-09.
What conditions does trial NCT04263285 study?
This clinical trial studies the following conditions: Depression, Spinal Cord Injuries.
What interventions are being tested in trial NCT04263285?
The interventions under investigation include: rTMS (DEVICE).
Who is sponsoring clinical trial NCT04263285?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04263285 being conducted?
This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04263285's enrollment target sits among peer trials
14 648th of 679 higher than 30 of 679 other Depression trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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