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NCT06225245 · ClinicalTrials.gov registry record · NA
Augmenting Rehabilitation Outcomes and Functional Neuroplasticity Using Epidural Stimulation of Cervical Spinal Cord
A NA study of Spinal Cord Injuries and Cervical Spinal Cord Injury, sponsored by The Methodist Hospital Research Institute.
- Recruiting
- Registry status
- NA
- Development phase
- 12
- Enrollment target
- 1
- Study location
NCT06225245: Recruiting NA study of Spinal Cord Injuries and Cervical Spinal Cord Injury, sponsored by The Methodist Hospital Research Institute.
NCT06225245 is a NA study of Spinal Cord Injuries and Cervical Spinal Cord Injury that is actively recruiting participants, run by The Methodist Hospital Research Institute. The registered enrollment target is 12 participants, below the 62-participant average among 202 other Spinal Cord Injuries trials with a reported enrollment target (81% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06225245, a NA study of Spinal Cord Injuries and Cervical Spinal Cord Injury, is actively recruiting participants, sponsored by The Methodist Hospital Research Institute.
- RECRUITING
- Registry status
- NA
- Development phase
- 12 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this study is to investigate the effects of cervical epidural spinal stimulation with upper extremity training. This is an investigational study. The device used for epidural spinal stimulation (ESS) to deliver spinal stimulation is called the CoverEdgeX 32 Surgical Lead system. This device is approved by the Food and Drug Administration (FDA) for the treatment of severe pain and to manage chronic pain when other treatments have not been effective. In this study, the device is considered an investigational device because it is not approved for use in the treatment of spinal cord injury
Primary Outcome
Neuromotor outcomes in the upper limb muscles will be assessed, specifically targeting the upper arm, forearm, wrist, and fine motor movements. Measurements will be conducted during voluntary effort without spinal stimulation, as well as in the presence of Epidural Spinal Stimulation (ESS). The force output will be quantified in newtons (N), while the magnitude of EMG signals will be measured and expressed in millivolts (mV).
Conditions Studied
Interventions
- DEVICE Epidural Spinal Stimulation (ESS)
Study Locations (1)
Texas
- The Methodist Hospital Research Institute - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2024-08-06 |
| Est. Completion | 2027-01-01 |
| Phase | NA |
What NCT06225245 shows while recruiting
NCT06225245 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 62-participant average among 202 other Spinal Cord Injuries trials with a reported enrollment target (81% lower).
The record links to 2 conditions, with Spinal Cord Injuries appearing as the primary indexed condition, and to 1 intervention - of which Epidural Spinal Stimulation (ESS) is the first listed.
NCT06225245 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT06225245 about?
NCT06225245 is a clinical study titled "Augmenting Rehabilitation Outcomes and Functional Neuroplasticity Using Epidural Stimulation of Cervical Spinal Cord". The goal of this study is to investigate the effects of cervical epidural spinal stimulation with upper extremity training. This is an investigational study. The device used for epidural spinal stimulation (ESS) to deliver spinal stimulation is called the CoverEdgeX 32 Surgical Lead system. This de...
What is the current status of trial NCT06225245?
This trial is currently recruiting. It is a NA study. The enrollment target is 12 participants. The study started on 2024-08-06. Estimated completion is 2027-01-01.
What conditions does trial NCT06225245 study?
This clinical trial studies the following conditions: Spinal Cord Injuries, Cervical Spinal Cord Injury.
What interventions are being tested in trial NCT06225245?
The interventions under investigation include: Epidural Spinal Stimulation (ESS) (DEVICE).
Who is sponsoring clinical trial NCT06225245?
This trial is sponsored by The Methodist Hospital Research Institute, which has 126 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06225245 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Spinal Cord Injuries
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06225245's enrollment target sits among peer trials
12 165th of 202 higher than 30 of 202 other Spinal Cord Injuries trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Spinal Cord Injuries trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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