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NCT05756894 · ClinicalTrials.gov registry record · NA

Neurostimulation for Respiratory Function After Spinal Cord Injury

A NA study of Spinal Cord Injuries and Cervical Spinal Cord Injury, sponsored by Shirley Ryan AbilityLab.

Recruiting
Registry status
NA
Development phase
10
Enrollment target
1
Study location

NCT05756894: Recruiting NA study of Spinal Cord Injuries and Cervical Spinal Cord Injury, sponsored by Shirley Ryan AbilityLab.

NCT05756894 is a NA study of Spinal Cord Injuries and Cervical Spinal Cord Injury that is actively recruiting participants, run by Shirley Ryan AbilityLab. The registered enrollment target is 10 participants, below the 62-participant average among 202 other Spinal Cord Injuries trials with a reported enrollment target (84% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05756894, a NA study of Spinal Cord Injuries and Cervical Spinal Cord Injury, is actively recruiting participants, sponsored by Shirley Ryan AbilityLab.

RECRUITING
Registry status
NA
Development phase
10 participants
Enrollment target
1
Study location

Study Summary

The purpose of this research study is to learn more about the connections between the brain, nerves, and diaphragm after experiencing a cervical spinal cord injury (SCI).The main question it aims to answer is: Changes in respiratory function and recovery using stimulation and respiratory exercise training in spinal cord-injured individuals. Participants will complete a maximum of 55 study visits. They will be asked to complete about 40 treatment sessions which include multiple stimulation sessions over the scalp and neck, followed by about 60 minutes of respiratory training. Assessment sessions will be completed prior at baseline, after 20 sessions and after 40 sessions of study treatment.

Primary Outcome

Transcranial magnetic stimuli (TMS) will be delivered to the optimal scalp position for activation of the diaphragm muscle. The optimal scalp position will be determined by moving the coil in small steps along the diaphragm representation of the primary motor cortex to find the region where the largest MEP can be evoked with the minimum intensity in the targeted muscles.

Interventions

  • DEVICE Neurostimulation
  • OTHER Repiratory training

Study Locations (1)

Illinois

  • Shirley Ryan Ability Lab - Chicago

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2023-02-28
Est. Completion 2026-12-31
Phase NA
Shirley Ryan AbilityLab

138 total trials

What NCT05756894 shows while recruiting

NCT05756894 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 62-participant average among 202 other Spinal Cord Injuries trials with a reported enrollment target (84% lower).

The record links to 3 conditions, with Spinal Cord Injuries appearing as the primary indexed condition, and to 2 interventions - of which Neurostimulation is the first listed.

NCT05756894 reports a single indexed study location in Illinois.

Frequently Asked Questions

What is clinical trial NCT05756894 about?

NCT05756894 is a clinical study titled "Neurostimulation for Respiratory Function After Spinal Cord Injury". The purpose of this research study is to learn more about the connections between the brain, nerves, and diaphragm after experiencing a cervical spinal cord injury (SCI).The main question it aims to answer is: Changes in respiratory function and recovery using stimulation and respiratory exercise t...

What is the current status of trial NCT05756894?

This trial is currently recruiting. It is a NA study. The enrollment target is 10 participants. The study started on 2023-02-28. Estimated completion is 2026-12-31.

What conditions does trial NCT05756894 study?

This clinical trial studies the following conditions: Spinal Cord Injuries, Cervical Spinal Cord Injury, Respiratory Function Impaired.

What interventions are being tested in trial NCT05756894?

The interventions under investigation include: Neurostimulation (DEVICE), Repiratory training (OTHER).

Who is sponsoring clinical trial NCT05756894?

This trial is sponsored by Shirley Ryan AbilityLab, which has 138 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05756894 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Spinal Cord Injuries

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05756894's enrollment target sits among peer trials

10 175th of 202 higher than 24 of 202 other Spinal Cord Injuries trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Spinal Cord Injuries trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05756894, the US trial registry maintained by the National Library of Medicine. NCT05756894 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.