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ClinicalTrials.gov 43 recruiting now official registry

Solid Tumors clinical trials

43 of 127 indexed Solid Tumors trials are currently recruiting.

127 US clinical trials · 43 currently recruiting

Solid Tumors is the subject of 127 registered US clinical trials on ClinicalTrials.gov, 43 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 117 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 8 of these trials.

The research picture

Solid Tumors has 127 registered US clinical trials, 43 of them open to new participants right now, about 34% of the total.

43
recruiting participants now
34%
of trials open to enrollment
4
in Phase 3–4 (later-stage)
8
top sponsor: M.D. Anderson Cancer Center
Phase 1102Phase 215Phase 33Phase 41

Active & Recent Trials

127 total, page 2 of 3

ACTIVE NOT RECRUITING Phase 1 165 participants

The Effects of Ginseng on Cancer-Related Fatigue

M.D. Anderson Cancer Center

NCT01375114

ACTIVE NOT RECRUITING Phase 1 161 participants

Safety, Tolerability, and Immunogenicity of mRNA-4157 Alone and in Combination in Participants With Solid Tumors

ModernaTX

NCT03313778

ACTIVE NOT RECRUITING Phase 1 144 participants

A Study of ADRX-0706 in Select Advanced Solid Tumors

Adcentrx Therapeutics

NCT06036121

ACTIVE NOT RECRUITING Phase 2 132 participants

Dexamethasone for Symptom Burden in Advanced Cancer Patients

M.D. Anderson Cancer Center

NCT00489307

ACTIVE NOT RECRUITING Phase 2 128 participants

Study Of Palbociclib Combined With Chemotherapy In Pediatric Patients With Recurrent/Refractory Solid Tumors

Pfizer

NCT03709680

ACTIVE NOT RECRUITING Phase 1 123 participants

A Study of Runimotamab in Participants With Locally Advanced or Metastatic HER2-Expressing Cancers

Genentech

NCT03448042

ACTIVE NOT RECRUITING Phase 1 89 participants

A Study to Evaluate the Safety and Tolerability of ETC-1922159 as a Single Agent and in Combination With Pembrolizumab in Advanced Solid Tumours

EDDC (Experimental Drug Development Centre), A*STAR Research Entities

NCT02521844

ACTIVE NOT RECRUITING Phase 1 69 participants

Study Of Entrectinib (Rxdx-101) in Children and Adolescents With Locally Advanced Or Metastatic Solid Or Primary CNS Tumors And/Or Who Have No Satisfactory Treatment Options

Hoffmann-La Roche

NCT02650401

ACTIVE NOT RECRUITING Phase 3 68 participants

Continued Access Study for Participants Deriving Benefit in Pfizer-Sponsored Avelumab Parent Studies That Are Closing

Pfizer

NCT05059522

ACTIVE NOT RECRUITING Early Phase 1 60 participants

Study of the Effects of Pre-surgical Aerobic Exercise on Patients With Solid Tumors

Memorial Sloan Kettering Cancer Center

NCT03813615

ACTIVE NOT RECRUITING Phase 1 45 participants

Study of GS-9911 With or Without Antibody Treatment for Adults With Solid Tumors

Gilead Sciences

NCT06082960

ACTIVE NOT RECRUITING Phase 1 36 participants

A Study in People With Advanced Cancer to Test How Well Different Doses of BI 770371 Alone or in Combination With Ezabenlimab Are Tolerated

Boehringer Ingelheim

NCT05327946

ACTIVE NOT RECRUITING Phase 1 30 participants

A Study to Evaluate INCB186748 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation

Incyte Corporation

NCT06818812

ACTIVE NOT RECRUITING Phase 1 28 participants

Research Study Utilizing Expanded Multi-antigen Specific Lymphocytes for the Treatment of Solid Tumors

Children's National Research Institute

NCT02789228

ACTIVE NOT RECRUITING Phase 1 18 participants

Cyclophosphamide Followed by Intravenous and Intraperitoneal Infusion of Autologous T Cells Genetically Engineered to Secrete IL-12 and to Target the MUC16ecto Antigen in Patients With Recurrent MUC16ecto+ Solid Tumors

Memorial Sloan Kettering Cancer Center

NCT02498912

ACTIVE NOT RECRUITING Early Phase 1 17 participants

Study of Pembrolizumab Following Surgery in Patients With Microsatellite Instability High (MSI-H) Solid Tumors

Memorial Sloan Kettering Cancer Center

NCT03832569

ACTIVE NOT RECRUITING Phase 1 9 participants

A Study to Evaluate INCB177054 in Participants With Select Advanced or Metastatic Solid Tumors

Incyte Corporation

NCT06873789

COMPLETED Phase 2 730 participants

Study of Cabozantinib (XL184) in Adults With Advanced Malignancies

Exelixis

NCT00940225

COMPLETED Phase 1 295 participants

An Investigational Immuno-therapy Study of Experimental Medication BMS-986156, Given by Itself or in Combination With Nivolumab in Patients With Solid Cancers or Cancers That Have Spread.

Bristol-Myers Squibb

NCT02598960

COMPLETED Phase 1 277 participants

Hormone Receptor Positive Disease Across Solid Tumor Types: A Phase I Study of Single-Agent Hormone Blockade and Combination Approaches With Targeted Agents to Provide Synergy and Overcome Resistance

M.D. Anderson Cancer Center

NCT01197170

COMPLETED Phase 1 260 participants

A Study Evaluating Bemarituzumab in Solid Tumors With Fibroblast Growth Factor Receptor 2b (FGFR2b) Overexpression

Amgen

NCT05325866

COMPLETED Phase 1 229 participants

A Study of LY2880070 in Participants With Advanced or Metastatic Cancer

Esperas Pharma

NCT02632448

COMPLETED Phase 1 184 participants

Phase 1b/2 Study of Carfilzomib in Relapsed Solid Tumors, Multiple Myeloma, or Lymphoma

Amgen

NCT00531284

COMPLETED Phase 2 176 participants

Allo Non-Myeloablative SCT Utilizing Mis-Matched Family Member Stem Cells Purged Using Campath

David Rizzieri, MD

NCT00580034

COMPLETED Phase 1 152 participants

A Study Evaluating Intermittent and Continuous OSI-906 and Weekly Paclitaxel in Patients With Recurrent Epithelial Ovarian Cancer (and Other Solid Tumors)

Astellas Pharma

NCT00889382

COMPLETED Phase 1 149 participants

A Phase 1/2 Study of INCB001158 in Combination With Chemotherapy in Subjects With Solid Tumors

Incyte Corporation

NCT03314935

COMPLETED Phase 1 119 participants

Combination Therapy With NC-6004 and Gemcitabine in Advanced Solid Tumors or Non-Small Cell Lung, Biliary and Bladder Cancer

NanoCarrier Co.

NCT02240238

COMPLETED Phase 1 106 participants

A Dose-escalation, Expansion Study of ARX788, in Advanced Solid Tumors Subjects With HER2 Expression (ACE-Pan Tumor 01)

Ambrx

NCT03255070

COMPLETED Phase 1 103 participants

AMG386 Comb w. Either Pegylated Liposomal Doxorubicin or Topotecan Subjects w. Advanced Recurrent Epithelial Ovarian CR

Amgen

NCT00770536

COMPLETED Phase 1 91 participants

Clinical Trial of ARQ 761 in Advanced Solid Tumors

University of Texas Southwestern Medical Center

NCT01502800

COMPLETED Phase 1 87 participants

Dose Escalation Study to Assess the Safety and Tolerability of Genz-644282 in Patients With Solid Tumors

Genzyme, a Sanofi Company

NCT00942799

COMPLETED Phase 2 84 participants

Brentuximab Vedotin in Patients With CD30-positive Nonlymphomatous Malignancies

Seagen

NCT01461538

COMPLETED Phase 1 83 participants

A Phase 1 Trial of CBL0137 in Patients With Metastatic or Unresectable Advanced Solid Neoplasm

Incuron

NCT01905228

COMPLETED Phase 1 73 participants

A Bioequivalence Study Between the Proposed and Current Talazoparib Capsule Formulation and Food Effect Study for the Proposed Talazoparib Capsule Formulation in Participants With Advanced Solid Tumors

Pfizer

NCT04672460

COMPLETED Phase 1 70 participants

A Study of Intravenous (IV) Cergutuzumab Amunaleukin and Atezolizumab in Combination in Participants With Locally Advanced and/or Metastatic Solid Tumors

Hoffmann-La Roche

NCT02350673

COMPLETED Phase 2 70 participants

Reproducibility of 18F Uptake by Solid Tumors Using PET Imaging Following Intravenous Administration of (18F) Injection

GE Healthcare

NCT00918281

COMPLETED Phase 1 64 participants

A Study of Tor Kinase Inhibitor in Advanced Tumors

AstraZeneca

NCT00731263

COMPLETED Phase 1 64 participants

Dose Escalation, Multi-arm Study of MLN4924 Plus Docetaxel, Gemcitabine, or Combination of Carboplatin and Paclitaxel in Participants With Solid Tumors

Millennium Pharmaceuticals

NCT01862328

COMPLETED Phase 2 63 participants

Dose/ Schedule Finding Trial of Romiplostim for Chemotherapy-Induced Thrombocytopenia (CIT) in Non-Small Cell Lung Cancer (NSCLC)

Amgen

NCT00413283

COMPLETED Phase 1 60 participants

Phase I Study of IPI-504 and Docetaxel in Patients With Advanced Solid Tumors

Infinity Pharmaceuticals

NCT00606814

COMPLETED Phase 1 58 participants

Oral ONC201 in Treating Patients With Advanced Solid Tumors

Rutgers, The State University of New Jersey

NCT02250781

COMPLETED Phase 1 57 participants

Phase 1 Study Of Aurora Kinase Inhibitor PF-03814735 In Patients With Advanced Solid Tumors

Pfizer

NCT00424632

COMPLETED Phase 1 55 participants

Safety, Tolerability and Pharmacokinetic (PK) of Concomitant Esomeprazole and Rifampin, and QT Study on Single and Multiple-doses of Alisertib

Millennium Pharmaceuticals

NCT01844583

COMPLETED Phase 1 50 participants

Dasatinib in Combination With Bevacizumab to Treat Advanced Solid Tumors

National Cancer Institute (NCI)

NCT01445509

COMPLETED Phase 1 50 participants

Safety Study of Sterile Compound C31510 for Injection to Subjects With Solid Tumors

BPGbio

NCT01251562

COMPLETED Phase 2 48 participants

Allo Non-myeloablative SCT Utilizing Matched Family Member Stem Cells Purged Using Campath

David Rizzieri, MD

NCT00578942

COMPLETED Phase 1 48 participants

Phase I Study of CBP501 and Cisplatin in Patients With Advanced Refractory Solid Tumors

CanBas Co.

NCT00551512

COMPLETED Phase 1 46 participants

A First-in-human Study to Evaluate the Safety, Tolerability and Pharmacokinetics of DS-6051b

Nuvation Bio

NCT02279433

COMPLETED Phase 1 45 participants

Phase I Study of TAS-106 in Combo With Carboplatin

M.D. Anderson Cancer Center

NCT00752011

COMPLETED Phase 1 45 participants

Dose Finding, Safety and Tolerability Study for AC220 to Treat Advanced Solid Tumors

Daiichi Sankyo

NCT01049893

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Phase Distribution

PhaseTrial count
Phase 1 102
Phase 2 15
Phase 3 3
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Solid Tumors Trial Landscape

127 indexed Solid Tumors studies · 43 recruiting (34%).

Phase mix: 4 late (III/IV) vs 117 early (I/II).

Top sponsor: M.D. Anderson Cancer Center (8 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Solid Tumors?

PlainTrial tracks 127 US clinical trials for Solid Tumors, of which 43 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Solid Tumors?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.