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NCT06818812 · ClinicalTrials.gov registry record · Phase 1
A Study to Evaluate INCB186748 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation
A Phase 1 study of Solid Tumors, sponsored by Incyte Corporation.
- Active
- Registry status
- Phase 1
- Development phase
- 30
- Enrollment target
- 9
- Study locations
NCT06818812 is a Phase 1 study of Solid Tumors that is active but no longer recruiting, run by Incyte Corporation. The registered enrollment target is 30 participants, below the 284-participant average among 125 other Solid Tumors trials with a reported enrollment target (89% lower). The trial reports 9 study locations across 9 states.
The verdict
NCT06818812, a Phase 1 study of Solid Tumors, is active but no longer recruiting, sponsored by Incyte Corporation.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 30 participants
- Enrollment target
- 9
- Study locations
Study Summary
The purpose of this study is to evaluate INCB186748 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation.
Conditions Studied
Interventions
- DRUG Cetuximab
- DRUG mFOLFIRINOX
- DRUG GEMNabP
- DRUG INCB186748
Study Locations (9)
California
- UCLA Healthcare Hematology-Oncology - Santa Monica
Colorado
- Sarah Cannon Research Institue At Healthone - Denver
District of Columbia
- Georgetown University Hospital - Washington D.C.
Florida
- Florida Cancer Specialists - Sarasota
Maryland
- Sidney Kimmel Comprehensive Cancer Center At Johns Hopkins - Baltimore
New Jersey
- Hackensack University Medical Center - Hackensack
Pennsylvania
- Jefferson University Hospitals - Philadelphia
Tennessee
- Scri Oncology Partners - Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2025-03-27 |
| Est. Completion | 2027-03-27 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06818812
The ClinicalTrials.gov registry entry for NCT06818812 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 284-participant average among 125 other Solid Tumors trials with a reported enrollment target (89% lower). The listed sponsor is Incyte Corporation, which has 239 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Solid Tumors appearing as the primary indexed condition, and to 4 interventions - of which Cetuximab is the first listed.
NCT06818812 reports 9 study locations spanning 9 distinct geographic areas - top geographies include California, Colorado, District of Columbia.
Frequently Asked Questions
What is clinical trial NCT06818812 about?
NCT06818812 is a clinical study titled "A Study to Evaluate INCB186748 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation". The purpose of this study is to evaluate INCB186748 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation.
What is the current status of trial NCT06818812?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2025-03-27. Estimated completion is 2027-03-27.
What conditions does trial NCT06818812 study?
This clinical trial studies the following conditions: Solid Tumors.
What interventions are being tested in trial NCT06818812?
The interventions under investigation include: Cetuximab (DRUG), mFOLFIRINOX (DRUG), GEMNabP (DRUG), INCB186748 (DRUG).
Who is sponsoring clinical trial NCT06818812?
This trial is sponsored by Incyte Corporation, which has 239 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06818812 being conducted?
This trial has 9 study locations across California, Colorado, District of Columbia, Florida, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.