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A Study to Evaluate INCB177054 in Participants With Select Advanced or Metastatic Solid Tumors
NCT06873789 · View on ClinicalTrials.gov ↗
Study Summary
This study will be conducted to evaluate INCB177054 given as monotherapy or in combination with retifanlimab in participants with select advanced or metastatic solid Tumors.
Conditions Studied
Interventions
- DRUG Retifanlimab
- DRUG INCB177054
Study Locations (9)
California
- The Angeles Clinic and Research Institute — Los Angeles
- Valkyrie Clinical Trials — Panorama City
Florida
- University of Florida Health Shands Hospital — Gainesville
Michigan
- Cancer and Hematology Centers of Western Michigan-Start Midwest — Grand Rapids
New Jersey
- Hackensack University Medical Center — Hackensack
North Carolina
- Carolina Bio Oncology — Huntersville
Oregon
- Providence Cancer Institute Franz Clinic — Portland
Pennsylvania
- Upmc Cancercenter — Pittsburgh
Texas
- South Texas Accelerated Research Therapeutics — San Antonio
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2025-06-30 |
| Est. Completion | 2028-10-30 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06873789
The ClinicalTrials.gov registry entry for NCT06873789 describes a study currently listed as active not recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 9 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Incyte Corporation, which has 163 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 3 conditions, with Advanced Solid Tumors appearing as the primary indexed condition, and to 2 interventions — of which Retifanlimab is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06873789 reports 9 study locations spanning 8 distinct geographic areas — top geographies include California, Florida, Michigan. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06873789 about?
NCT06873789 is a clinical study titled "A Study to Evaluate INCB177054 in Participants With Select Advanced or Metastatic Solid Tumors". This study will be conducted to evaluate INCB177054 given as monotherapy or in combination with retifanlimab in participants with select advanced or metastatic solid Tumors.
What is the current status of trial NCT06873789?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 9 participants. The study started on 2025-06-30. Estimated completion is 2028-10-30.
What conditions does trial NCT06873789 study?
This clinical trial studies the following conditions: Advanced Solid Tumors, Solid Tumors, Metastatic Solid Tumors. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06873789?
The interventions under investigation include: Retifanlimab (DRUG), INCB177054 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06873789?
This trial is sponsored by Incyte Corporation, which has 163 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06873789 being conducted?
This trial has 9 study locations across California, Florida, Michigan, New Jersey, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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