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NCT00489307 · ClinicalTrials.gov registry record · Phase 2
Dexamethasone for Symptom Burden in Advanced Cancer Patients
A Phase 2 study of Solid Tumors, sponsored by M.D. Anderson Cancer Center.
- Active
- Registry status
- Phase 2
- Development phase
- 132
- Enrollment target
- 2
- Study locations
NCT00489307: Active Phase 2 study of Solid Tumors, sponsored by M.D. Anderson Cancer Center.
NCT00489307 is a Phase 2 study of Solid Tumors that is active but no longer recruiting, run by M.D. Anderson Cancer Center. The registered enrollment target is 132 participants, below the 284-participant average among 125 other Solid Tumors trials with a reported enrollment target (54% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00489307, a Phase 2 study of Solid Tumors, is active but no longer recruiting, sponsored by M.D. Anderson Cancer Center.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 132 participants
- Enrollment target
- 2
- Study locations
Study Summary
The goal of this clinical research study is to learn if dexamethasone can help to control symptoms such as fatigue, pain, nausea, weight loss, loss of appetite, sleep problems, and/or depression in patients with advanced cancer.
Primary Outcome
FACIT Fatigue Subscale is a short, 13-item, easy to administer tool that measures an individual's level of fatigue during their usual daily activities over the past week. The level of fatigue is measured on a four point Likert scale (4 = not at all fatigued to 0 = very much fatigued). The total score range is from 0-52. The higher the score, the lower the fatigue level. It was measured as change in symptom score from Baseline to Day 15.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Dexamethasone
Study Locations (2)
Texas
- Lyndon Baines Johnson Hospital - Houston
- University of Texas MD Anderson Cancer Center - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 132 participants |
| Start Date | 2006-02-02 |
| Est. Completion | 2028-02-28 |
| Phase | Phase 2 |
What the registry record for NCT00489307 still lists
NCT00489307 is an interventional study that assigns participants to a tested intervention. The registered 132 participants enrollment target is mid-sized for trials with a published cap, below the 284-participant average among 125 other Solid Tumors trials with a reported enrollment target (54% lower).
The record links to 1 condition, with Solid Tumors appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT00489307 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT00489307 about?
NCT00489307 is a clinical study titled "Dexamethasone for Symptom Burden in Advanced Cancer Patients". The goal of this clinical research study is to learn if dexamethasone can help to control symptoms such as fatigue, pain, nausea, weight loss, loss of appetite, sleep problems, and/or depression in patients with advanced cancer.
What is the current status of trial NCT00489307?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 132 participants. The study started on 2006-02-02. Estimated completion is 2028-02-28.
What conditions does trial NCT00489307 study?
This clinical trial studies the following conditions: Solid Tumors.
What interventions are being tested in trial NCT00489307?
The interventions under investigation include: Placebo (DRUG), Dexamethasone (DRUG).
Who is sponsoring clinical trial NCT00489307?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00489307 being conducted?
This trial has 2 study locations across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Solid Tumors
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00489307's enrollment target sits among peer trials
132 44th of 125 higher than 82 of 125 other Solid Tumors trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Solid Tumors trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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