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ClinicalTrials.gov 26 recruiting now full pipeline #93 of 28,707 conditions

Psoriasis: full-pipeline trial registry

26 of 127 indexed Psoriasis trials are currently recruiting.

Corpus placement: #93 of 28,707 conditions by registered trial count.

127 US clinical trials · 26 currently recruiting · #93 of 28,707 conditions by registered trial count

Psoriasis: 127 US clinical trials tracked, 26 recruiting.

Psoriasis is the subject of 127 registered US clinical trials on ClinicalTrials.gov, 26 of them currently open to new participants. 50 are in Phase 3-4 (later-stage) and 36 in Phase 1-2 (earlier-stage). The most active sponsor is Bristol-Myers Squibb, running 8 of these trials.

Enrollment posture brief

Registry condition psoriasis

OPEN 26 | RECR 20% | LATE 50 | EARLY 36 | RANK #93 | SPON 8

Nearest open-share peer: Healthy (21% recruiting · 1,096 trials)

Head and Neck Squamous Cell 56.8%Sarcoma45%Solid Tumors33.9%Smoking21.8%Psoriasis (this)20%
Open-enrollment share among volume-matched conditions near Psoriasis

Psoriasis lists 26 open slots (20% of 127 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Psoriasis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Psoriasis is recruiting below its size-band peers.

    26 of 127 indexed trials (20.5%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Psoriasis trials is spread across many organizations.

    Bristol-Myers Squibb accounts for 8 of 127 trials (6.3%). 65 distinct sponsors appear on at least one study for this condition label.

  3. Typical Psoriasis enrolment sits around 84 participants.

    Median target enrolment is 84 among the 126 trials that report a genuine target (sentinel values excluded). 68 of those (54%) plan for fewer than 100 participants.

  4. Psoriasis research is mostly interventional.

    101 interventional and 26 observational studies make up this index (79.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 120Phase 216Phase 326Phase 424

Open and recent trials

127 total, page 1 of 3

RECRUITING 2,500 participants

IMPACT - AndHealth Autoimmune Research Registry

AndHealth

NCT05883371

RECRUITING 1,500 participants

A Real-world Observational Study to Compare Effectiveness of Deucravacitinib Vs Apremilast in Adults With Plaque Psoriasis

Bristol-Myers Squibb

NCT05744466

RECRUITING 1,000 participants

Psorcast Mobile Study

Sage Bionetworks

NCT05621369

RECRUITING NA 520 participants

Prevention of Cardiovascular Disease and Mortality in Patients With Psoriasis or Psoriatic Arthritis

University of Pennsylvania

NCT05908240

RECRUITING Phase 1 300 participants

Nivolumab in Treating Patients With Autoimmune Disorders and Advanced, Metastatic, or Unresectable Cancer

National Cancer Institute (NCI)

NCT03816345

RECRUITING 300 participants

Metabolic Profiling of Immune Responses in Immune-mediated Diseases

National Institute of Allergy and Infectious Diseases (NIAID)

NCT04864886

RECRUITING 240 participants

Skin Microbial Ecology in Atopic Dermatitis

University of Rochester

NCT04170244

RECRUITING 200 participants

Stelara and Tremfya Pregnancy Exposure Registry OTIS Autoimmune Diseases in Pregnancy Project

University of California, San Diego

NCT02103361

RECRUITING Phase 4 200 participants

A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)

Eli Lilly and Company

NCT06857942

RECRUITING Phase 4 176 participants

Multi-Center PAMPA Study

NYU Langone Health

NCT05004727

RECRUITING Phase 1 132 participants

Evaluate the Safety and Pharmacokinetics/Pharmacodynamics of HS-20118

Jiangsu Hansoh Pharmaceutical Co.

NCT06846710

RECRUITING 125 participants

Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors

M.D. Anderson Cancer Center

NCT04751396

RECRUITING NA 100 participants

A Study to Evaluate the Impact of a Magnolia Officinalis Dietary Supplement on Immune Biomarkers in Subjects With Psoriasis

Sirt3

NCT07471048

RECRUITING Phase 1 90 participants

Study of SFA002 in Patients with Mild to Moderate Psoriasis Plaques

SFA Therapeutics

NCT05642182

RECRUITING Phase 4 56 participants

Development of Predictive Psoriasis Response Endotypes Using Single Cell Transcriptomics

University Hospitals Cleveland Medical Center

NCT05270733

RECRUITING Phase 4 45 participants

A Safety and Pharmacokinetics Study of IDP-122 Lotion in Pediatric Participants With Plaque Psoriasis

Bausch Health Americas

NCT03987763

RECRUITING Phase 4 45 participants

A Safety and Pharmacokinetics Study of IDP-118 Lotion in Pediatric Participants With Plaque Psoriasis

Bausch Health Americas

NCT03988439

RECRUITING NA 36 participants

Mediterranean Diet vs no Dietary Intervention for Improving Signs and Symptoms of Psoriasis in Patients Treated With Anti-IL-17 or Anti-IL-23 Inhibitors

University Hospitals Cleveland Medical Center

NCT06399432

RECRUITING NA 30 participants

An Open-Label, Pilot Study to Evaluate the Efficacy of Narrowband Ultraviolet-B Phototherapy Three Times Weekly for Twelve Weeks in Moderate-to-Severe Psoriasis Patients

Psoriasis Treatment Center of Central New Jersey

NCT03392337

RECRUITING Phase 4 30 participants

Enstilar in Combination With Enbrel or Humira for Plaque Psoriasis

Psoriasis Treatment Center of Central New Jersey

NCT03827876

RECRUITING Phase 4 25 participants

Duobrii in Combination With Biologics

Psoriasis Treatment Center of Central New Jersey

NCT04119102

RECRUITING Phase 4 25 participants

ILUMYA in Combination With HALOG Ointment 0.1% for Plaque Psoriasis.

Psoriasis Treatment Center of Central New Jersey

NCT04347473

RECRUITING Phase 4 25 participants

Taltz in Combination With Enstilar for Psoriasis

Psoriasis Treatment Center of Central New Jersey

NCT04372277

RECRUITING Phase 1 16 participants

Maximal Usage Pharmacokinetics and Safety Study of ARQ-154 Foam 0.3% in Pediatric Participants With Scalp and Body Psoriasis

Arcutis Biotherapeutics

NCT07340216

RECRUITING 13 participants

Regulation of Inflammatory Genes in Psoriasis

University of Alabama at Birmingham

NCT03125655

RECRUITING NA 5 participants

Use of Total-Body PET to Quantify Systemic and Cutaneous Inflammation in Psoriasis Patients Before and After Intervention With a Nutritionally Balanced Diet

University of California, Davis

NCT06574178

ACTIVE NOT RECRUITING 15,842 participants

Psoriasis Longitudinal Assessment and Registry

Janssen Scientific Affairs

NCT00508547

ACTIVE NOT RECRUITING 15,000 participants

A Longitudinal Observational Study of Patients Undergoing Therapy for IMISC

Target PharmaSolutions

NCT03661866

ACTIVE NOT RECRUITING Phase 3 1,680 participants

Long-term Safety and Efficacy of ESK-001 in Moderate to Severe Plaque Psoriasis

Alumis

NCT06846541

ACTIVE NOT RECRUITING Phase 3 1,466 participants

Long-Term Study That Measures the Safety and Efficacy of Deucravacitinib (BMS-986165) in Participants With Psoriasis

Bristol-Myers Squibb

NCT04036435

ACTIVE NOT RECRUITING 925 participants

OTIS Cimzia Pregnancy Registry

University of California, San Diego

NCT01797224

ACTIVE NOT RECRUITING 833 participants

A Study on the Safety of Deucravacitinib Exposure in Pregnant Women and Their Offspring

Bristol-Myers Squibb

NCT06710470

ACTIVE NOT RECRUITING Phase 3 250 participants

Ixekizumab Concomitantly Administered With Tirzepatide in Adults With Moderate-to-Severe Plaque Psoriasis and Obesity or Overweight

Eli Lilly and Company

NCT06588283

ACTIVE NOT RECRUITING 233 participants

Apremilast Pregnancy Exposure Registry

University of California, San Diego

NCT02775500

ACTIVE NOT RECRUITING Phase 3 132 participants

Study to Evaluate Adverse Events and Change in Disease Activity in Participants Between 6 and 17 Years With Moderate to Severe Plaque Psoriasis Treated With Subcutaneous (SC) Injection of Risankizumab Who Have Completed Participation in Study M19-977

AbbVie

NCT04862286

ACTIVE NOT RECRUITING Phase 3 120 participants

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Subcutaneously Administered Guselkumab for the Treatment of Chronic Plaque Psoriasis in Pediatric Participants

Janssen Research & Development

NCT03451851

ACTIVE NOT RECRUITING NA 60 participants

Role of Intermittent Fasting in Psoriasis and Psoriatic Arthritis

Ohio State University

NCT05590247

ACTIVE NOT RECRUITING NA 40 participants

Deucravacitinib Adherence Study

Wake Forest University Health Sciences

NCT05570955

ACTIVE NOT RECRUITING NA 20 participants

Use of Transcutaneous Electrical Nerve Stimulation for Reducing Biologic Injection Site Pain(TENS Study)

Wake Forest University Health Sciences

NCT04058652

ACTIVE NOT RECRUITING Phase 4 20 participants

Risankizumab Long-term Remission Study

Jaehwan Kim

NCT04630652

ACTIVE NOT RECRUITING Phase 4 2 participants

An Open-label, Single-dose Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Brodalumab in Pediatric Subjects

Bausch Health Americas

NCT03240809

COMPLETED 1,846 participants

A Study to Evaluate Psoriasis Outcomes and Safety Events in Patients With Chronic Moderate to Severe Plaque Psoriasis (RESPONSE)

Genentech

NCT00096928

COMPLETED Phase 3 1,296 participants

A Phase 3 Study in Participants With Moderate to Severe Psoriasis

Eli Lilly and Company

NCT01474512

COMPLETED Phase 3 1,224 participants

A Phase 3 Study in Participants With Moderate to Severe Psoriasis (UNCOVER-2)

Eli Lilly and Company

NCT01597245

COMPLETED NA 943 participants

Asthma and Atopic Dermatitis Validation of PROMIS Pediatric Instruments

Northwestern University

NCT03051347

COMPLETED Phase 3 901 participants

A One-Year Study To Evaluate The Effects And Safety Of CP-690,550 In Patients With Moderate To Severe Chronic Plaque Psoriasis

Pfizer

NCT01276639

COMPLETED Phase 3 658 participants

A Study to Assess the Safety and Effectiveness of Tacrolimus Cream in the Treatment of Psoriasis

Astellas Pharma

NCT00293891

COMPLETED 600 participants

Assessment of Digital Imaging as a Tool for Diagnosing Psoriasis, Hand Rashes and Unusual Moles

National Cancer Institute (NCI)

NCT00005781

COMPLETED Phase 3 542 participants

Evaluate the Efficacy and Safety of M518101 in Subjects With Plaque Psoriasis

Maruho North America

NCT01878461

COMPLETED Phase 3 494 participants

A Study to Investigate Interchangeability of ABP 654 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis

Amgen

NCT04761627

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Phase Distribution

PhaseTrial count
Phase 1 20
Phase 2 16
Phase 3 26
Phase 4 24

Named interventions

Most-linked intervention names on Psoriasis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
13 trials
Ustekinumab Drug
7 trials
Apremilast Drug
6 trials
Placebo Other
6 trials
Guselkumab Drug
5 trials
Risankizumab Drug
4 trials
M518101 Drug
3 trials
Vehicle Drug
3 trials

US sites by state

Facility locations filed on Psoriasis trials. A trial with sites in several states counts in each.

California 63 trials
Florida 40 trials
New York 31 trials
Illinois 26 trials
Texas 25 trials
Indiana 25 trials
Georgia 22 trials
North Carolina 21 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Psoriasis page

127 registered trials, 26 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Psoriasis condition card totals 127 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.