Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Psoriasis clinical trials
Every US clinical trial registered for Psoriasis — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
127 US clinical trials · 26 currently recruiting
The research picture
Psoriasis has 127 registered US clinical trials, 26 of them open to new participants right now — about 20% of the total.
- 26
- recruiting participants now
- 20%
- of trials open to enrollment
- 50
- in Phase 3–4 (later-stage)
- 8
- top sponsor: Bristol-Myers Squibb
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
IMPACT - AndHealth Autoimmune Research Registry
AndHealth
NCT05883371
A Real-world Observational Study to Compare Effectiveness of Deucravacitinib Vs Apremilast in Adults With Plaque Psoriasis
Bristol-Myers Squibb
NCT05744466
Psorcast Mobile Study
Sage Bionetworks
NCT05621369
Prevention of Cardiovascular Disease and Mortality in Patients With Psoriasis or Psoriatic Arthritis
University of Pennsylvania
NCT05908240
Nivolumab in Treating Patients With Autoimmune Disorders and Advanced, Metastatic, or Unresectable Cancer
National Cancer Institute (NCI)
NCT03816345
Metabolic Profiling of Immune Responses in Immune-mediated Diseases
National Institute of Allergy and Infectious Diseases (NIAID)
NCT04864886
Skin Microbial Ecology in Atopic Dermatitis
University of Rochester
NCT04170244
Stelara and Tremfya Pregnancy Exposure Registry OTIS Autoimmune Diseases in Pregnancy Project
University of California, San Diego
NCT02103361
A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)
Eli Lilly and Company
NCT06857942
Multi-Center PAMPA Study
NYU Langone Health
NCT05004727
Evaluate the Safety and Pharmacokinetics/Pharmacodynamics of HS-20118
Jiangsu Hansoh Pharmaceutical Co.
NCT06846710
Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors
M.D. Anderson Cancer Center
NCT04751396
A Study to Evaluate the Impact of a Magnolia Officinalis Dietary Supplement on Immune Biomarkers in Subjects With Psoriasis
Sirt3
NCT07471048
Study of SFA002 in Patients with Mild to Moderate Psoriasis Plaques
SFA Therapeutics
NCT05642182
Development of Predictive Psoriasis Response Endotypes Using Single Cell Transcriptomics
University Hospitals Cleveland Medical Center
NCT05270733
A Safety and Pharmacokinetics Study of IDP-122 Lotion in Pediatric Participants With Plaque Psoriasis
Bausch Health Americas
NCT03987763
A Safety and Pharmacokinetics Study of IDP-118 Lotion in Pediatric Participants With Plaque Psoriasis
Bausch Health Americas
NCT03988439
Mediterranean Diet vs no Dietary Intervention for Improving Signs and Symptoms of Psoriasis in Patients Treated With Anti-IL-17 or Anti-IL-23 Inhibitors
University Hospitals Cleveland Medical Center
NCT06399432
An Open-Label, Pilot Study to Evaluate the Efficacy of Narrowband Ultraviolet-B Phototherapy Three Times Weekly for Twelve Weeks in Moderate-to-Severe Psoriasis Patients
Psoriasis Treatment Center of Central New Jersey
NCT03392337
Enstilar in Combination With Enbrel or Humira for Plaque Psoriasis
Psoriasis Treatment Center of Central New Jersey
NCT03827876
Duobrii in Combination With Biologics
Psoriasis Treatment Center of Central New Jersey
NCT04119102
ILUMYA in Combination With HALOG Ointment 0.1% for Plaque Psoriasis.
Psoriasis Treatment Center of Central New Jersey
NCT04347473
Taltz in Combination With Enstilar for Psoriasis
Psoriasis Treatment Center of Central New Jersey
NCT04372277
Maximal Usage Pharmacokinetics and Safety Study of ARQ-154 Foam 0.3% in Pediatric Participants With Scalp and Body Psoriasis
Arcutis Biotherapeutics
NCT07340216
Regulation of Inflammatory Genes in Psoriasis
University of Alabama at Birmingham
NCT03125655
Use of Total-Body PET to Quantify Systemic and Cutaneous Inflammation in Psoriasis Patients Before and After Intervention With a Nutritionally Balanced Diet
University of California, Davis
NCT06574178
Psoriasis Longitudinal Assessment and Registry
Janssen Scientific Affairs
NCT00508547
A Longitudinal Observational Study of Patients Undergoing Therapy for IMISC
Target PharmaSolutions
NCT03661866
Long-term Safety and Efficacy of ESK-001 in Moderate to Severe Plaque Psoriasis
Alumis
NCT06846541
Long-Term Study That Measures the Safety and Efficacy of Deucravacitinib (BMS-986165) in Participants With Psoriasis
Bristol-Myers Squibb
NCT04036435
OTIS Cimzia Pregnancy Registry
University of California, San Diego
NCT01797224
A Study on the Safety of Deucravacitinib Exposure in Pregnant Women and Their Offspring
Bristol-Myers Squibb
NCT06710470
Ixekizumab Concomitantly Administered With Tirzepatide in Adults With Moderate-to-Severe Plaque Psoriasis and Obesity or Overweight
Eli Lilly and Company
NCT06588283
Apremilast Pregnancy Exposure Registry
University of California, San Diego
NCT02775500
Study to Evaluate Adverse Events and Change in Disease Activity in Participants Between 6 and 17 Years With Moderate to Severe Plaque Psoriasis Treated With Subcutaneous (SC) Injection of Risankizumab Who Have Completed Participation in Study M19-977
AbbVie
NCT04862286
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Subcutaneously Administered Guselkumab for the Treatment of Chronic Plaque Psoriasis in Pediatric Participants
Janssen Research & Development
NCT03451851
Role of Intermittent Fasting in Psoriasis and Psoriatic Arthritis
Ohio State University
NCT05590247
Deucravacitinib Adherence Study
Wake Forest University Health Sciences
NCT05570955
Use of Transcutaneous Electrical Nerve Stimulation for Reducing Biologic Injection Site Pain(TENS Study)
Wake Forest University Health Sciences
NCT04058652
Risankizumab Long-term Remission Study
Jaehwan Kim
NCT04630652
An Open-label, Single-dose Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Brodalumab in Pediatric Subjects
Bausch Health Americas
NCT03240809
A Study to Evaluate Psoriasis Outcomes and Safety Events in Patients With Chronic Moderate to Severe Plaque Psoriasis (RESPONSE)
Genentech
NCT00096928
A Phase 3 Study in Participants With Moderate to Severe Psoriasis
Eli Lilly and Company
NCT01474512
A Phase 3 Study in Participants With Moderate to Severe Psoriasis (UNCOVER-2)
Eli Lilly and Company
NCT01597245
Asthma and Atopic Dermatitis Validation of PROMIS Pediatric Instruments
Northwestern University
NCT03051347
A One-Year Study To Evaluate The Effects And Safety Of CP-690,550 In Patients With Moderate To Severe Chronic Plaque Psoriasis
Pfizer
NCT01276639
A Study to Assess the Safety and Effectiveness of Tacrolimus Cream in the Treatment of Psoriasis
Astellas Pharma
NCT00293891
Assessment of Digital Imaging as a Tool for Diagnosing Psoriasis, Hand Rashes and Unusual Moles
National Cancer Institute (NCI)
NCT00005781
Evaluate the Efficacy and Safety of M518101 in Subjects With Plaque Psoriasis
Maruho North America
NCT01878461
A Study to Investigate Interchangeability of ABP 654 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis
Amgen
NCT04761627
Long Term Study to Evaluate Safety and Efficacy of M518101 in Subjects With Plaque Psoriasis
Maruho North America
NCT01908595
A Study to Assess the Efficacy and Safety of PPC-06 (Tepilamide Fumarate)
Dr. Reddy's Laboratories Limited
NCT03421197
Impact of the Severity of Pediatric Psoriasis on Childhood Body Mass Index
Northwestern University
NCT00879944
A Comparison of DFD01 Spray Versus Comp01 Lotion, Vehicle Spray and Vehicle Lotion in Subjects With Moderate Psoriasis
Primus Pharmaceuticals
NCT01947491
Study of Subcutaneous Risankizumab Injection Compared to Oral Apremilast Tablets to Assess Change in Disease Activity And Adverse Events in Adult Participants With Moderate Plaque Psoriasis Who Are Candidates for Systemic Therapy
AbbVie
NCT04908475
Risankizumab Versus Secukinumab for Participants With Moderate to Severe Plaque Psoriasis
AbbVie
NCT03478787
A Study of the Efficacy and Safety of Apremilast (CC-10004) in Subjects With Moderate to Severe Plaque Psoriasis of the Scalp
Amgen
NCT03123471
Collaborative Connected Health (CCH) for PCORI
University of Southern California
NCT02358135
A Phase 2b Study of Baricitinib in Participants With Moderate to Severe Psoriasis
Eli Lilly and Company
NCT01490632
Study to Evaluate Effectiveness and Safety in Subjects With Moderate to Severe Psoriasis
Bristol-Myers Squibb
NCT02931838
Phase 3b Safety and Efficacy Study of Apremilast to Treat Moderate to Severe Plaque-plaque Psoriasis
Amgen
NCT01690299
An Efficacy and Safety Study of Two Dose Levels of Certolizumab Pegol (CZP) in Subjects With Plaque Psoriasis (PSO)
UCB Biopharma S.P.R.L.
NCT02326298
Measuring the Treatment Preferences of Participants in Japan With Moderate-to-Severe Psoriasis (PsO) Using Discrete Choice Experiment
Bristol-Myers Squibb
NCT05065762
A Study to Evaluate the Efficacy and Safety of Two Dose Levels of Certolizumab Pegol (CZP) in Subjects With Plaque Psoriasis (PSO)
UCB Biopharma S.P.R.L.
NCT02326272
A Dose Ranging Study of the Effect of Ruxolitinib Phosphate Cream When Applied to Participants With Plaque Psoriasis
Incyte Corporation
NCT00778700
A Study to Evaluate the Effect of Deucravacitinib on Quality of Life in Participants With Plaque Psoriasis in a Community Setting
Bristol-Myers Squibb
NCT05701995
BI 655066 Dose Ranging in Psoriasis, Active Comparator Ustekinumab
Boehringer Ingelheim
NCT02054481
A Long-term Extension Study of Apremilast (CC-10004) in Pediatric Subjects From 6 Through 17 Years of Age With Moderate to Severe Plaque Psoriasis
Amgen
NCT04175613
Open Label Study of Adalimumab in Subjects Who Have a Sub-optimal Response to Systemic Therapy or Phototherapy
Abbott
NCT00566722
Study to Evaluate the Efficacy and Safety of JTE-451 in Subjects With Moderate to Severe Plaque Psoriasis
Akros Pharma
NCT03832738
A Study in Participants With Moderate to Severe Psoriasis
Eli Lilly and Company
NCT01107457
A Study of Subcutaneous Risankizumab Injection for Pediatric Participants With Moderate to Severe Plaque Psoriasis to Assess Change in Disease Symptoms
AbbVie
NCT04435600
A Study to Explore Efficacy and Safety of ASP015K in Subjects With Moderate to Severe Psoriasis
Astellas Pharma
NCT01096862
Effects of Desoximetasone Spray 0.25% in Patients With Moderate to Severe Plaque Psoriasis
Sun Pharmaceutical Industries
NCT01206660
A Study to Assess Usability of Risankizumab Autoinjector Combination Product in Participants With Moderate to Severe Plaque Psoriasis
AbbVie
NCT03875508
Serum, Cellular and Imaging Markers of Arthritis in Psoriasis Patients
University of Rochester
NCT02413801
Randomized Study of PH-10 for Psoriasis
Provectus Pharmaceuticals
NCT01247818
Topically Applied IDP-118 Lotion and HP Monad Lotion in Subjects With Moderate to Severe Plaque Psoriasis
Bausch Health Americas
NCT03058744
Genetic Analysis of Pediatric Psoriasis
Northwestern University
NCT03768284
Mind Matters: A High Touch, Low Cost Approach to Improving Mental Health Outcomes in Patients With Psoriatic Diseases
Elaine Husni
NCT05571696
Efficacy and Safety Study of Guselkumab in the Treatment of Participants With Moderate to Severe Plaque-Type Psoriasis
Janssen Research & Development
NCT02905331
Study Evaluating The Safety And Tolerability Of ILV-094 In Subjects With Psoriasis
Wyeth is now a wholly owned subsidiary of Pfizer
NCT00563524
A Study of R3421 in Patients With Moderate to Severe Chronic Plaque Psoriasis.
Hoffmann-La Roche
NCT00504270
Evaluation of Clinical Outcomes in an Online Teledermatology Model for the Management of Psoriasis
University of California, Davis
NCT00971477
Prevalence of Sleep Disturbances in Psoriasis
Wake Forest University Health Sciences
NCT00895375
Olux E Foam and Sorilux Foam Combination Therapy for the Maintenance of Treatment Response in Patients With Moderate Plaque Psoriasis
Leon Kircik, M.D.
NCT01745133
Characterization of Lipoprotein Composition and Function in Pediatric Psoriasis Before and After Treatment
Northwestern University
NCT03791216
Study of the Efficacy of Cloderm® Cream in the Treatment of Moderate Plaque Psoriasis
Promius Pharma
NCT01714544
Sleep, Circadian Rhythm & Skin Health
University Hospitals Cleveland Medical Center
NCT02457000
Multiple Dose Escalation Study In Medically Stable Subjects With Psoriasis
Pfizer
NCT01736696
An Investigational Study of Cyclosporine on Experimental Medication BMS-986165 in Healthy Male Participants
Bristol-Myers Squibb
NCT03419910
A Safety, Tolerability and Pharmacokinetics Study of Topical Ointment YR001 in Adult Healthy Volunteers
Hangzhou Yirui Pharmaceutical Technology Co.
NCT05718921
A Study to Evaluate BMS-986165 Tablet Formulation Relative to BMS-986165 Capsule Formulation and the Effect of a High-Fat/ High-Calorie Meal and Increased Gastric pH on the BMS-986165 Tablet Formulation
Bristol-Myers Squibb
NCT03254784
Vascular Inflammation in Psoriasis-Ustekinumab (VIP-U)
University of Pennsylvania
NCT02187172
A Study of Safety, Tolerability and Pharmacokinetics of Apremilast (CC-10004) in Pediatric Subjects With Moderate to Severe Plaque Psoriasis
Amgen
NCT02576678
Study of the Clinical Activity, Safety, and Tolerability of SRT2104 in Subjects With Moderate to Severe Plaque-Type Psoriasis
Sirtris, a GSK Company
NCT01154101
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Doses of AbGn-168 in Psoriasis
Boehringer Ingelheim
NCT00848055
Single Ascending Dose Study of PRX003 in Healthy Subjects
Prothena Biosciences Limited
NCT02458677
MIcrovascular dysfuNction In Moderate-severe Psoriasis
Marcelo F. Di Carli, MD, FACC
NCT04271540
The Quality of Life Study in Psoriasis Patients After Ustekinumab Treatment
University of California, San Francis
NCT01511315
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 20 |
| Phase 2 | 16 |
| Phase 3 | 26 |
| Phase 4 | 24 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Psoriasis Trial Landscape
ClinicalTrials.gov lists 127 US studies indexed under Psoriasis, and 26 of those are currently open to recruitment — roughly 20% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Psoriasis shows 50 late-stage studies (Phase 3 and Phase 4 combined) alongside 36 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Psoriasis is led by Bristol-Myers Squibb with 8 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 100 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Psoriasis?
PlainTrial tracks 127 US clinical trials for Psoriasis, of which 26 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Psoriasis?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.