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ClinicalTrials.gov 26 recruiting now official registry

Psoriasis clinical trials

26 of 127 indexed Psoriasis trials are currently recruiting.

127 US clinical trials · 26 currently recruiting

Psoriasis is the subject of 127 registered US clinical trials on ClinicalTrials.gov, 26 of them currently open to new participants. 50 are in Phase 3-4 (later-stage) and 36 in Phase 1-2 (earlier-stage). The most active sponsor is Bristol-Myers Squibb, running 8 of these trials.

The research picture

Psoriasis has 127 registered US clinical trials, 26 of them open to new participants right now, about 20% of the total.

26
recruiting participants now
20%
of trials open to enrollment
50
in Phase 3–4 (later-stage)
8
top sponsor: Bristol-Myers Squibb
Phase 120Phase 216Phase 326Phase 424

Active & Recent Trials

127 total, page 1 of 3

RECRUITING 2,500 participants

IMPACT - AndHealth Autoimmune Research Registry

AndHealth

NCT05883371

RECRUITING 1,500 participants

A Real-world Observational Study to Compare Effectiveness of Deucravacitinib Vs Apremilast in Adults With Plaque Psoriasis

Bristol-Myers Squibb

NCT05744466

RECRUITING 1,000 participants

Psorcast Mobile Study

Sage Bionetworks

NCT05621369

RECRUITING NA 520 participants

Prevention of Cardiovascular Disease and Mortality in Patients With Psoriasis or Psoriatic Arthritis

University of Pennsylvania

NCT05908240

RECRUITING Phase 1 300 participants

Nivolumab in Treating Patients With Autoimmune Disorders and Advanced, Metastatic, or Unresectable Cancer

National Cancer Institute (NCI)

NCT03816345

RECRUITING 300 participants

Metabolic Profiling of Immune Responses in Immune-mediated Diseases

National Institute of Allergy and Infectious Diseases (NIAID)

NCT04864886

RECRUITING 240 participants

Skin Microbial Ecology in Atopic Dermatitis

University of Rochester

NCT04170244

RECRUITING 200 participants

Stelara and Tremfya Pregnancy Exposure Registry OTIS Autoimmune Diseases in Pregnancy Project

University of California, San Diego

NCT02103361

RECRUITING Phase 4 200 participants

A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)

Eli Lilly and Company

NCT06857942

RECRUITING Phase 4 176 participants

Multi-Center PAMPA Study

NYU Langone Health

NCT05004727

RECRUITING Phase 1 132 participants

Evaluate the Safety and Pharmacokinetics/Pharmacodynamics of HS-20118

Jiangsu Hansoh Pharmaceutical Co.

NCT06846710

RECRUITING 125 participants

Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors

M.D. Anderson Cancer Center

NCT04751396

RECRUITING NA 100 participants

A Study to Evaluate the Impact of a Magnolia Officinalis Dietary Supplement on Immune Biomarkers in Subjects With Psoriasis

Sirt3

NCT07471048

RECRUITING Phase 1 90 participants

Study of SFA002 in Patients with Mild to Moderate Psoriasis Plaques

SFA Therapeutics

NCT05642182

RECRUITING Phase 4 56 participants

Development of Predictive Psoriasis Response Endotypes Using Single Cell Transcriptomics

University Hospitals Cleveland Medical Center

NCT05270733

RECRUITING Phase 4 45 participants

A Safety and Pharmacokinetics Study of IDP-122 Lotion in Pediatric Participants With Plaque Psoriasis

Bausch Health Americas

NCT03987763

RECRUITING Phase 4 45 participants

A Safety and Pharmacokinetics Study of IDP-118 Lotion in Pediatric Participants With Plaque Psoriasis

Bausch Health Americas

NCT03988439

RECRUITING NA 36 participants

Mediterranean Diet vs no Dietary Intervention for Improving Signs and Symptoms of Psoriasis in Patients Treated With Anti-IL-17 or Anti-IL-23 Inhibitors

University Hospitals Cleveland Medical Center

NCT06399432

RECRUITING NA 30 participants

An Open-Label, Pilot Study to Evaluate the Efficacy of Narrowband Ultraviolet-B Phototherapy Three Times Weekly for Twelve Weeks in Moderate-to-Severe Psoriasis Patients

Psoriasis Treatment Center of Central New Jersey

NCT03392337

RECRUITING Phase 4 30 participants

Enstilar in Combination With Enbrel or Humira for Plaque Psoriasis

Psoriasis Treatment Center of Central New Jersey

NCT03827876

RECRUITING Phase 4 25 participants

Duobrii in Combination With Biologics

Psoriasis Treatment Center of Central New Jersey

NCT04119102

RECRUITING Phase 4 25 participants

ILUMYA in Combination With HALOG Ointment 0.1% for Plaque Psoriasis.

Psoriasis Treatment Center of Central New Jersey

NCT04347473

RECRUITING Phase 4 25 participants

Taltz in Combination With Enstilar for Psoriasis

Psoriasis Treatment Center of Central New Jersey

NCT04372277

RECRUITING Phase 1 16 participants

Maximal Usage Pharmacokinetics and Safety Study of ARQ-154 Foam 0.3% in Pediatric Participants With Scalp and Body Psoriasis

Arcutis Biotherapeutics

NCT07340216

RECRUITING 13 participants

Regulation of Inflammatory Genes in Psoriasis

University of Alabama at Birmingham

NCT03125655

RECRUITING NA 5 participants

Use of Total-Body PET to Quantify Systemic and Cutaneous Inflammation in Psoriasis Patients Before and After Intervention With a Nutritionally Balanced Diet

University of California, Davis

NCT06574178

ACTIVE NOT RECRUITING 15,842 participants

Psoriasis Longitudinal Assessment and Registry

Janssen Scientific Affairs

NCT00508547

ACTIVE NOT RECRUITING 15,000 participants

A Longitudinal Observational Study of Patients Undergoing Therapy for IMISC

Target PharmaSolutions

NCT03661866

ACTIVE NOT RECRUITING Phase 3 1,680 participants

Long-term Safety and Efficacy of ESK-001 in Moderate to Severe Plaque Psoriasis

Alumis

NCT06846541

ACTIVE NOT RECRUITING Phase 3 1,466 participants

Long-Term Study That Measures the Safety and Efficacy of Deucravacitinib (BMS-986165) in Participants With Psoriasis

Bristol-Myers Squibb

NCT04036435

ACTIVE NOT RECRUITING 925 participants

OTIS Cimzia Pregnancy Registry

University of California, San Diego

NCT01797224

ACTIVE NOT RECRUITING 833 participants

A Study on the Safety of Deucravacitinib Exposure in Pregnant Women and Their Offspring

Bristol-Myers Squibb

NCT06710470

ACTIVE NOT RECRUITING Phase 3 250 participants

Ixekizumab Concomitantly Administered With Tirzepatide in Adults With Moderate-to-Severe Plaque Psoriasis and Obesity or Overweight

Eli Lilly and Company

NCT06588283

ACTIVE NOT RECRUITING 233 participants

Apremilast Pregnancy Exposure Registry

University of California, San Diego

NCT02775500

ACTIVE NOT RECRUITING Phase 3 132 participants

Study to Evaluate Adverse Events and Change in Disease Activity in Participants Between 6 and 17 Years With Moderate to Severe Plaque Psoriasis Treated With Subcutaneous (SC) Injection of Risankizumab Who Have Completed Participation in Study M19-977

AbbVie

NCT04862286

ACTIVE NOT RECRUITING Phase 3 120 participants

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Subcutaneously Administered Guselkumab for the Treatment of Chronic Plaque Psoriasis in Pediatric Participants

Janssen Research & Development

NCT03451851

ACTIVE NOT RECRUITING NA 60 participants

Role of Intermittent Fasting in Psoriasis and Psoriatic Arthritis

Ohio State University

NCT05590247

ACTIVE NOT RECRUITING NA 40 participants

Deucravacitinib Adherence Study

Wake Forest University Health Sciences

NCT05570955

ACTIVE NOT RECRUITING NA 20 participants

Use of Transcutaneous Electrical Nerve Stimulation for Reducing Biologic Injection Site Pain(TENS Study)

Wake Forest University Health Sciences

NCT04058652

ACTIVE NOT RECRUITING Phase 4 20 participants

Risankizumab Long-term Remission Study

Jaehwan Kim

NCT04630652

ACTIVE NOT RECRUITING Phase 4 2 participants

An Open-label, Single-dose Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Brodalumab in Pediatric Subjects

Bausch Health Americas

NCT03240809

COMPLETED 1,846 participants

A Study to Evaluate Psoriasis Outcomes and Safety Events in Patients With Chronic Moderate to Severe Plaque Psoriasis (RESPONSE)

Genentech

NCT00096928

COMPLETED Phase 3 1,296 participants

A Phase 3 Study in Participants With Moderate to Severe Psoriasis

Eli Lilly and Company

NCT01474512

COMPLETED Phase 3 1,224 participants

A Phase 3 Study in Participants With Moderate to Severe Psoriasis (UNCOVER-2)

Eli Lilly and Company

NCT01597245

COMPLETED NA 943 participants

Asthma and Atopic Dermatitis Validation of PROMIS Pediatric Instruments

Northwestern University

NCT03051347

COMPLETED Phase 3 901 participants

A One-Year Study To Evaluate The Effects And Safety Of CP-690,550 In Patients With Moderate To Severe Chronic Plaque Psoriasis

Pfizer

NCT01276639

COMPLETED Phase 3 658 participants

A Study to Assess the Safety and Effectiveness of Tacrolimus Cream in the Treatment of Psoriasis

Astellas Pharma

NCT00293891

COMPLETED 600 participants

Assessment of Digital Imaging as a Tool for Diagnosing Psoriasis, Hand Rashes and Unusual Moles

National Cancer Institute (NCI)

NCT00005781

COMPLETED Phase 3 542 participants

Evaluate the Efficacy and Safety of M518101 in Subjects With Plaque Psoriasis

Maruho North America

NCT01878461

COMPLETED Phase 3 494 participants

A Study to Investigate Interchangeability of ABP 654 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis

Amgen

NCT04761627

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Phase Distribution

PhaseTrial count
Phase 1 20
Phase 2 16
Phase 3 26
Phase 4 24

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Psoriasis Trial Landscape

127 indexed Psoriasis studies · 26 recruiting (20%).

Phase mix: 50 late (III/IV) vs 36 early (I/II).

Top sponsor: Bristol-Myers Squibb (8 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Psoriasis?

PlainTrial tracks 127 US clinical trials for Psoriasis, of which 26 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Psoriasis?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.