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Psoriasis clinical trials
26 of 127 indexed Psoriasis trials are currently recruiting.
127 US clinical trials · 26 currently recruiting
Psoriasis is the subject of 127 registered US clinical trials on ClinicalTrials.gov, 26 of them currently open to new participants. 50 are in Phase 3-4 (later-stage) and 36 in Phase 1-2 (earlier-stage). The most active sponsor is Bristol-Myers Squibb, running 8 of these trials.
The research picture
Psoriasis has 127 registered US clinical trials, 26 of them open to new participants right now, about 20% of the total.
- 26
- recruiting participants now
- 20%
- of trials open to enrollment
- 50
- in Phase 3–4 (later-stage)
- 8
- top sponsor: Bristol-Myers Squibb
Active & Recent Trials
127 total, page 1 of 3
IMPACT - AndHealth Autoimmune Research Registry
AndHealth
NCT05883371
A Real-world Observational Study to Compare Effectiveness of Deucravacitinib Vs Apremilast in Adults With Plaque Psoriasis
Bristol-Myers Squibb
NCT05744466
Psorcast Mobile Study
Sage Bionetworks
NCT05621369
Prevention of Cardiovascular Disease and Mortality in Patients With Psoriasis or Psoriatic Arthritis
University of Pennsylvania
NCT05908240
Nivolumab in Treating Patients With Autoimmune Disorders and Advanced, Metastatic, or Unresectable Cancer
National Cancer Institute (NCI)
NCT03816345
Metabolic Profiling of Immune Responses in Immune-mediated Diseases
National Institute of Allergy and Infectious Diseases (NIAID)
NCT04864886
Skin Microbial Ecology in Atopic Dermatitis
University of Rochester
NCT04170244
Stelara and Tremfya Pregnancy Exposure Registry OTIS Autoimmune Diseases in Pregnancy Project
University of California, San Diego
NCT02103361
A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)
Eli Lilly and Company
NCT06857942
Multi-Center PAMPA Study
NYU Langone Health
NCT05004727
Evaluate the Safety and Pharmacokinetics/Pharmacodynamics of HS-20118
Jiangsu Hansoh Pharmaceutical Co.
NCT06846710
Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors
M.D. Anderson Cancer Center
NCT04751396
A Study to Evaluate the Impact of a Magnolia Officinalis Dietary Supplement on Immune Biomarkers in Subjects With Psoriasis
Sirt3
NCT07471048
Study of SFA002 in Patients with Mild to Moderate Psoriasis Plaques
SFA Therapeutics
NCT05642182
Development of Predictive Psoriasis Response Endotypes Using Single Cell Transcriptomics
University Hospitals Cleveland Medical Center
NCT05270733
A Safety and Pharmacokinetics Study of IDP-122 Lotion in Pediatric Participants With Plaque Psoriasis
Bausch Health Americas
NCT03987763
A Safety and Pharmacokinetics Study of IDP-118 Lotion in Pediatric Participants With Plaque Psoriasis
Bausch Health Americas
NCT03988439
Mediterranean Diet vs no Dietary Intervention for Improving Signs and Symptoms of Psoriasis in Patients Treated With Anti-IL-17 or Anti-IL-23 Inhibitors
University Hospitals Cleveland Medical Center
NCT06399432
An Open-Label, Pilot Study to Evaluate the Efficacy of Narrowband Ultraviolet-B Phototherapy Three Times Weekly for Twelve Weeks in Moderate-to-Severe Psoriasis Patients
Psoriasis Treatment Center of Central New Jersey
NCT03392337
Enstilar in Combination With Enbrel or Humira for Plaque Psoriasis
Psoriasis Treatment Center of Central New Jersey
NCT03827876
Duobrii in Combination With Biologics
Psoriasis Treatment Center of Central New Jersey
NCT04119102
ILUMYA in Combination With HALOG Ointment 0.1% for Plaque Psoriasis.
Psoriasis Treatment Center of Central New Jersey
NCT04347473
Taltz in Combination With Enstilar for Psoriasis
Psoriasis Treatment Center of Central New Jersey
NCT04372277
Maximal Usage Pharmacokinetics and Safety Study of ARQ-154 Foam 0.3% in Pediatric Participants With Scalp and Body Psoriasis
Arcutis Biotherapeutics
NCT07340216
Regulation of Inflammatory Genes in Psoriasis
University of Alabama at Birmingham
NCT03125655
Use of Total-Body PET to Quantify Systemic and Cutaneous Inflammation in Psoriasis Patients Before and After Intervention With a Nutritionally Balanced Diet
University of California, Davis
NCT06574178
Psoriasis Longitudinal Assessment and Registry
Janssen Scientific Affairs
NCT00508547
A Longitudinal Observational Study of Patients Undergoing Therapy for IMISC
Target PharmaSolutions
NCT03661866
Long-term Safety and Efficacy of ESK-001 in Moderate to Severe Plaque Psoriasis
Alumis
NCT06846541
Long-Term Study That Measures the Safety and Efficacy of Deucravacitinib (BMS-986165) in Participants With Psoriasis
Bristol-Myers Squibb
NCT04036435
OTIS Cimzia Pregnancy Registry
University of California, San Diego
NCT01797224
A Study on the Safety of Deucravacitinib Exposure in Pregnant Women and Their Offspring
Bristol-Myers Squibb
NCT06710470
Ixekizumab Concomitantly Administered With Tirzepatide in Adults With Moderate-to-Severe Plaque Psoriasis and Obesity or Overweight
Eli Lilly and Company
NCT06588283
Apremilast Pregnancy Exposure Registry
University of California, San Diego
NCT02775500
Study to Evaluate Adverse Events and Change in Disease Activity in Participants Between 6 and 17 Years With Moderate to Severe Plaque Psoriasis Treated With Subcutaneous (SC) Injection of Risankizumab Who Have Completed Participation in Study M19-977
AbbVie
NCT04862286
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Subcutaneously Administered Guselkumab for the Treatment of Chronic Plaque Psoriasis in Pediatric Participants
Janssen Research & Development
NCT03451851
Role of Intermittent Fasting in Psoriasis and Psoriatic Arthritis
Ohio State University
NCT05590247
Deucravacitinib Adherence Study
Wake Forest University Health Sciences
NCT05570955
Use of Transcutaneous Electrical Nerve Stimulation for Reducing Biologic Injection Site Pain(TENS Study)
Wake Forest University Health Sciences
NCT04058652
Risankizumab Long-term Remission Study
Jaehwan Kim
NCT04630652
An Open-label, Single-dose Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Brodalumab in Pediatric Subjects
Bausch Health Americas
NCT03240809
A Study to Evaluate Psoriasis Outcomes and Safety Events in Patients With Chronic Moderate to Severe Plaque Psoriasis (RESPONSE)
Genentech
NCT00096928
A Phase 3 Study in Participants With Moderate to Severe Psoriasis
Eli Lilly and Company
NCT01474512
A Phase 3 Study in Participants With Moderate to Severe Psoriasis (UNCOVER-2)
Eli Lilly and Company
NCT01597245
Asthma and Atopic Dermatitis Validation of PROMIS Pediatric Instruments
Northwestern University
NCT03051347
A One-Year Study To Evaluate The Effects And Safety Of CP-690,550 In Patients With Moderate To Severe Chronic Plaque Psoriasis
Pfizer
NCT01276639
A Study to Assess the Safety and Effectiveness of Tacrolimus Cream in the Treatment of Psoriasis
Astellas Pharma
NCT00293891
Assessment of Digital Imaging as a Tool for Diagnosing Psoriasis, Hand Rashes and Unusual Moles
National Cancer Institute (NCI)
NCT00005781
Evaluate the Efficacy and Safety of M518101 in Subjects With Plaque Psoriasis
Maruho North America
NCT01878461
A Study to Investigate Interchangeability of ABP 654 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis
Amgen
NCT04761627
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 20 |
| Phase 2 | 16 |
| Phase 3 | 26 |
| Phase 4 | 24 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Psoriasis Trial Landscape
127 indexed Psoriasis studies · 26 recruiting (20%).
Phase mix: 50 late (III/IV) vs 36 early (I/II).
Top sponsor: Bristol-Myers Squibb (8 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Psoriasis?
PlainTrial tracks 127 US clinical trials for Psoriasis, of which 26 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Psoriasis?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.