OncoMed Pharmaceuticals

Closed portfolio with an early-phase archive tilt

According to ClinicalTrials.gov-derived indexes, OncoMed Pharmaceuticals sits in the top decile of US sponsors by registered trial count (#626 of 15,742 sponsors by registered trial count).

25 total trials none currently recruiting 20 completed early-phase tilt top decile by trial count

OncoMed Pharmaceuticals: 25 sponsored US clinical trials, none currently recruiting.

OncoMed Pharmaceuticals sponsors 25 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 20 completed. 0 of these trials are in Phase 3-4 (later-stage) and 25 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Solid Tumors, with 2 trials.

Top-decile sponsor footprint

OncoMed Pharmaceuticals ranks in the top decile of sponsors by registered trial count (#626 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 39/100

20 of 25 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (80.0%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Indexed trials (enrollment closed)

25 total, page 1 of 1

TERMINATED Phase 1

A Study of OMP-336B11 in Subjects With Locally Advanced or Metastatic Tumors

NCT03295942

TERMINATED Phase 1

A Study of OMP-313M32 in Subjects With Locally Advanced or Metastatic Solid Tumors

NCT03119428

COMPLETED Phase 1

A Study of Brontictuzumab With Chemotherapy for Subjects With Previously Treated Metastatic Colorectal Cancer

NCT03031691

COMPLETED Phase 1

A Phase 1b Study of OMP-305B83 Plus Paclitaxel in Subjects With Ovarian, Peritoneal or Fallopian Tube Cancer

NCT03030287

TERMINATED Phase 1

A Study of OMP-305B83 in Subjects With Metastatic Colorectal Cancer

NCT03035253

COMPLETED Phase 1

A Phase 1b Study of Demcizumab Plus Pembrolizumab in Locally Advanced or Metastatic Solid Tumors

NCT02722954

COMPLETED Phase 1

A Phase 1a/b Dose Escalation Study of the Safety, Pharmacokinetics, and Pharmacodynamics of OMP-131R10

NCT02482441

COMPLETED Phase 2

Study of Gemcitabine, Abraxane® Plus Placebo Versus Gemcitabine, Abraxane® Plus 1 or 2 Truncated Courses of Demcizumab in Subjects With 1st-Line Metastatic Pancreatic Ductal Adenocarcinoma

NCT02289898

COMPLETED Phase 2

A Study of Carboplatin, Pemetrexed Plus Placebo vs Carboplatin, Pemetrexed Plus 1 or 2 Truncated Courses of Demcizumab in Subjects With Non-Squamous Non-Small Cell Lung Cancer

NCT02259582

COMPLETED Phase 1

A Phase 1 Study of OMP-305B83 in Subjects With Solid Tumors

NCT02298387

COMPLETED Phase 1

Dose Escalation Study of OMP-54F28 in Combination With Paclitaxel and Carboplatin in Patients With Recurrent Platinum-Sensitive Ovarian Cancer

NCT02092363

COMPLETED Phase 1

Dose Escalation Study of OMP-54F28 in Combination With Sorafenib in Patients With Hepatocellular Cancer

NCT02069145

COMPLETED Phase 1

Dose Escalation Study of OMP-54F28 in Combination With Nab-Paclitaxel and Gemcitabine in Patients With Previously Untreated Stage IV Pancreatic Cancer

NCT02050178

COMPLETED Phase 1

A Study of Vantictumab (OMP-18R5) in Combination With Docetaxel in Patients With Previously Treated NSCLC

NCT01957007

COMPLETED Phase 1

A Study of Vantictumab (OMP-18R5) in Combination With Nab-Paclitaxel and Gemcitabine in Previously Untreated Stage IV Pancreatic Cancer

NCT02005315

COMPLETED Phase 1

A Study of Vantictumab (OMP-18R5) in Combination With Paclitaxel in Locally Recurrent or Metastatic Breast Cancer

NCT01973309

TERMINATED Phase 1

A Study of Demcizumab Plus Paclitaxel in Subjects With Platinum Resistant Ovarian

NCT01952249

COMPLETED Phase 1

A Dose Escalation Study of OMP-52M51 in Subjects With Solid Tumors

NCT01778439

COMPLETED Phase 1

A Dose Escalation Study of OMP-52M51 in Subjects With Lymphoid Malignancies

NCT01703572

COMPLETED Phase 1

A Phase 1b/2 Study of OMP-59R5 (Tarextumab) in Combination With Nab-Paclitaxel and Gemcitabine in Subjects With Previously Untreated Stage IV Pancreatic Cancer

NCT01647828

COMPLETED Phase 1

A Dose Escalation Study of OMP-54F28 in Subjects With Solid Tumors

NCT01608867

TERMINATED Phase 1

A Phase 1b/2 Study of OMP-59R5 (Tarextumab) in Combination With Etoposide and Platinum Therapy

NCT01859741

COMPLETED Phase 1

A Dose Escalation Study of OMP-18R5 in Subjects With Solid Tumors

NCT01345201

COMPLETED Phase 1

A Dose Escalation Study of OMP-59R5 in Subjects With Solid Tumors

NCT01277146

COMPLETED Phase 1

A Phase 1 Dose Escalation Study of OMP-21M18 in Subjects With Solid Tumors

NCT00744562

How the OncoMed Pharmaceuticals early-phase archive is shaped

25 indexed studies, none listed as recruiting (0% open); 20 completed (80%).

Phase mix: 0 late (III/IV) vs 25 early (I/II) (early-phase heavy).

Top condition: Solid Tumors (2 trials), 7 others listed.

How to read a closed sponsor archive

When recruiting_count is zero, the indexed set is completed or otherwise not open. Phase tilt still describes where archived studies sat on the investigational pathway. Re-check ClinicalTrials.gov before acting.

OncoMed Pharmaceuticals: archived-pipeline peers nationwide

Peers matched on 25 indexed studies with no current recruiting: volume and archive shape, not condition overlap.

OncoMed Pharmaceuticals sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 051015202530 0%5%10%15% Total trials Recruiting share OncoMed PharmaceuticalsArcus BiosciencesArcutis BiotherapeuticsArdelyxDrexel University College of Medicine10xBio22nd Century Group23andMe3-C Institute for Social Development
OncoMed Pharmaceuticals sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

OncoMed Pharmaceuticals sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 25 archived trials

Sponsors with similar archive density (± trial count)

What to do with this OncoMed Pharmaceuticals page

25 registered trials is a research-attention snapshot, not an endorsement of OncoMed Pharmaceuticals or any single study.

  • None of OncoMed Pharmaceuticals's trials are currently recruiting in this registry; that can change as new trials post, or check the broader research index. Browse research indexes
  • Solid Tumors is the condition OncoMed Pharmaceuticals studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Solid Tumors trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. OncoMed Pharmaceuticals pipeline card: 25 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.