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COMPLETED Phase 1

Phase I Study of IPI-504 and Docetaxel in Patients With Advanced Solid Tumors

NCT00606814 · View on ClinicalTrials.gov ↗

Study Summary

This study is a Phase I clinical trial of IPI-504 in combination with docetaxel (Taxotere).The purposes of the study are to determine: * the safety profile, * the highest dose of IPI-504 that can be given with docetaxel without causing severe side effects, and * to recommend a Phase II dose of the combination in patients with solid tumors.

Conditions Studied

Interventions

  • DRUG IPI-504, docetaxel

Study Locations (8)

New York

  • Roswell Park Cancer Institute — Buffalo
  • Memorial Sloan-Kettering Cancer Center — New York

Ohio

  • Gabrail Cancer Center — Canton
  • Gabrail Cancer Center — Dover

Arizona

  • TGen Clinical Research in Scottsdale — Scottsdale

Connecticut

  • Yale Cancer Center — New Haven

Florida

  • H. Lee Moffitt Cancer Center & Research Institute — Tampa

Pennsylvania

  • University of Pittsburgh Medical Center — Pittsburgh

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2007-12
Est. Completion 2011-12
Phase Phase 1

Sponsor

Infinity Pharmaceuticals

2 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00606814

The ClinicalTrials.gov registry entry for NCT00606814 describes a study currently listed as completed. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Infinity Pharmaceuticals, which has 2 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Solid Tumors appearing as the primary indexed condition, and to 1 intervention — of which IPI-504, docetaxel is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00606814 reports 8 study locations spanning 6 distinct geographic areas — top geographies include New York, Ohio, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00606814 about?

NCT00606814 is a clinical study titled "Phase I Study of IPI-504 and Docetaxel in Patients With Advanced Solid Tumors". This study is a Phase I clinical trial of IPI-504 in combination with docetaxel (Taxotere).The purposes of the study are to determine: * the safety profile, * the highest dose of IPI-504 that can be given with docetaxel without causing severe side effects, and * to recommend a Phase II dose of the ...

What is the current status of trial NCT00606814?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 60 participants. The study started on 2007-12. Estimated completion is 2011-12.

What conditions does trial NCT00606814 study?

This clinical trial studies the following conditions: Solid Tumors. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00606814?

The interventions under investigation include: IPI-504, docetaxel (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00606814?

This trial is sponsored by Infinity Pharmaceuticals, which has 2 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00606814 being conducted?

This trial has 8 study locations across Arizona, Connecticut, Florida, New York, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial