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NCT01197170 · ClinicalTrials.gov registry record · Phase 1

Hormone Receptor Positive Disease Across Solid Tumor Types: A Phase I Study of Single-Agent Hormone Blockade and Combination Approaches With Targeted Agents to Provide Synergy and Overcome Resistance

A Phase 1 study of Solid Tumors and Advanced Cancer, sponsored by M.D. Anderson Cancer Center.

Completed
Registry status
Phase 1
Development phase
277
Enrollment target
1
Study location

NCT01197170 is a Phase 1 study of Solid Tumors and Advanced Cancer that has completed, run by M.D. Anderson Cancer Center. The registered enrollment target is 277 participants, roughly in line with the 282-participant average among 125 other Solid Tumors trials with a reported enrollment target. The trial reports 1 study location across 1 state.

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The verdict

NCT01197170, a Phase 1 study of Solid Tumors and Advanced Cancer, has completed, sponsored by M.D. Anderson Cancer Center.

COMPLETED
Registry status
Phase 1
Development phase
277 participants
Enrollment target
1
Study location

Study Summary

The goal of this clinical research study to find the highest tolerated dose of anastrozole alone or in combination with either everolimus (Afinitor), sorafenib (Nexavar), erlotinib (Tarceva), fulvestrant (Faslodex), or bevacizumab (Avastin) that can be given to patients with advanced cancer. The safety of these drug combinations will also be studied.

Interventions

  • DRUG Bevacizumab
  • DRUG Anastrozole
  • DRUG Everolimus
  • DRUG Sorafenib
  • DRUG Erlotinib

Study Locations (1)

Texas

  • University of Texas MD Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 277 participants
Start Date 2010-09-07
Est. Completion 2021-01-13
Phase Phase 1

Sponsor

M.D. Anderson Cancer Center

2,692 total trials

What the Registry Record Tells You About NCT01197170

The ClinicalTrials.gov registry entry for NCT01197170 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 277 participants, a figure that helps gauge the scale of data the investigators plan to collect, roughly in line with the 282-participant average among 125 other Solid Tumors trials with a reported enrollment target. The listed sponsor is M.D. Anderson Cancer Center, which has 2,692 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Solid Tumors appearing as the primary indexed condition, and to 5 interventions - of which Bevacizumab is the first listed.

NCT01197170 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT01197170 about?

NCT01197170 is a clinical study titled "Hormone Receptor Positive Disease Across Solid Tumor Types: A Phase I Study of Single-Agent Hormone Blockade and Combination Approaches With Targeted Agents to Provide Synergy and Overcome Resistance". The goal of this clinical research study to find the highest tolerated dose of anastrozole alone or in combination with either everolimus (Afinitor), sorafenib (Nexavar), erlotinib (Tarceva), fulvestrant (Faslodex), or bevacizumab (Avastin) that can be given to patients with advanced cancer. The saf...

What is the current status of trial NCT01197170?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 277 participants. The study started on 2010-09-07. Estimated completion is 2021-01-13.

What conditions does trial NCT01197170 study?

This clinical trial studies the following conditions: Solid Tumors, Advanced Cancer.

What interventions are being tested in trial NCT01197170?

The interventions under investigation include: Bevacizumab (DRUG), Anastrozole (DRUG), Everolimus (DRUG), Sorafenib (DRUG), Erlotinib (DRUG).

Who is sponsoring clinical trial NCT01197170?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01197170 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.