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ClinicalTrials.gov 104 recruiting now early-phase tilt #53 of 28,707 conditions

Solid Tumor: early-phase trial registry

104 of 197 indexed Solid Tumor trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #53 of 28,707 conditions by registered trial count.

197 US clinical trials · 104 currently recruiting · #53 of 28,707 conditions by registered trial count

Solid Tumor: 197 US clinical trials tracked, 104 recruiting.

Solid Tumor is the subject of 197 registered US clinical trials on ClinicalTrials.gov, 104 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 165 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 11 of these trials.

Enrollment posture brief

Registry condition solid-tumor

OPEN 104 | RECR 53% | LATE 4 | EARLY 165 | RANK #53 | SPON 11

Nearest open-share peer: Metastatic Breast Cancer (53% recruiting · 140 trials)

Solid Tumor (this)53%Type 1 Diabetes39.7%Glioblastoma39%Overweight25.3%Rheumatoid Arthritis18.6%
Open-enrollment share among volume-matched conditions near Solid Tumor

Solid Tumor lists 104 open slots (53% of 197 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Solid Tumor on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Solid Tumor is recruiting above its size-band peers.

    104 of 197 indexed trials (52.8%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Solid Tumor trials is spread across many organizations.

    Memorial Sloan Kettering Cancer Center accounts for 11 of 197 trials (5.6%). 149 distinct sponsors appear on at least one study for this condition label.

  3. Typical Solid Tumor enrolment sits around 80 participants.

    Median target enrolment is 80 among the 197 trials that report a genuine target (sentinel values excluded). 108 of those (54.8%) plan for fewer than 100 participants.

  4. Solid Tumor research is mostly interventional.

    179 interventional and 18 observational studies make up this index (90.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 1150Phase 215Phase 31Phase 43

Open and recent trials

197 total, page 1 of 4

RECRUITING 10,000 participants

Natural History and Biospecimen Acquisition for Children and Adults With Rare Solid Tumors

National Cancer Institute (NCI)

NCT03739827

RECRUITING 5,000 participants

Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies

Children's Oncology Group

NCT00736749

RECRUITING 3,644 participants

Remote Digital Physiologic Data Collection in Cancer: An MSK Registry Protocol

Memorial Sloan Kettering Cancer Center

NCT05390827

RECRUITING Phase 1 1,314 participants

Study of Zanzalintinib in Combination With Immuno-Oncology Agents in Participants With Solid Tumors

Exelixis

NCT05176483

RECRUITING Phase 1 681 participants

A Study of ASP3082 in Adults With Advanced Solid Tumors

Astellas Pharma

NCT05382559

RECRUITING Phase 1 575 participants

FOG-001 in Locally Advanced or Metastatic Solid Tumors

Parabilis Medicines

NCT05919264

RECRUITING Phase 1 542 participants

A First-in-human, Dose Escalation and Dose Expansion Study of SAR445877 in Adult Participants With Advanced Solid Tumors

Sanofi

NCT05584670

RECRUITING Phase 1 500 participants

A Phase 1/2 Study of BHV-1510 (Previously PBI-410) in Advanced Solid Tumors

Biohaven Therapeutics

NCT06384807

RECRUITING Phase 1 410 participants

A Study to Evaluate Safety, Pharmacokinetics, and Activity of GDC-7035 as a Single Agent and in Combination in Patients With Advanced Solid Tumors

Genentech

NCT06619587

RECRUITING 400 participants

The Intersection of Oncology Care and Worker Well-Being

University of Colorado, Denver

NCT05250284

RECRUITING Phase 1 370 participants

A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)

Merck Sharp & Dohme

NCT02332668

RECRUITING Phase 1 364 participants

A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors

Astellas Pharma

NCT07094204

RECRUITING Phase 1 336 participants

Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion

Bristol-Myers Squibb

NCT05245500

RECRUITING Phase 1 332 participants

A Study of JZP815 Oral Capsules in Adult Participants With Advanced or Metastatic Solid Tumors Harboring Mitogen Activated Protein Kinase (MAPK) Pathway Alterations to Investigate the Safety, Dosing, and Antitumor Activity of JZP815

Jazz Pharmaceuticals

NCT05557045

RECRUITING Phase 1 330 participants

A Study of PYX-201 in Advanced Solid Tumors

Pyxis Oncology

NCT05720117

RECRUITING Phase 1 330 participants

Study of TJ033721 (Givastomig) in Subjects With Advanced or Metastatic Solid Tumors

I-Mab Biopharma US Limited

NCT04900818

RECRUITING Phase 1 316 participants

Phase 1a and Phase 2 Study for Safety, Preliminary Efficacy, PK and PD of ST-067

Simcha IL-18

NCT04787042

RECRUITING NA 285 participants

Psychotherapy Intervention for Latinos With Adv Cancer

Memorial Sloan Kettering Cancer Center

NCT04537936

RECRUITING Phase 1 263 participants

A Study of CUSP06 in Patients With Platinum-Refractory/Resistant Ovarian Cancer and Other Advanced Solid Tumors

OnCusp Therapeutics

NCT06234423

RECRUITING NA 234 participants

Adapting for Latinx Populations an Intervention That Involves Discussing and Sharing Patients' Health-Related Values

Memorial Sloan Kettering Cancer Center

NCT04942717

RECRUITING Phase 1 232 participants

A Study of SPX-303, a Bispecific Antibody Targeting LILRB2 and PD-L1 in Patients With Solid Tumors

SparX Biotech(Jiangsu) Co.

NCT06259552

RECRUITING Phase 1 230 participants

Indocyanine Green (ICG) Guided Tumor Resection

St. Jude Children's Research Hospital

NCT04084067

RECRUITING Phase 1 222 participants

A Study of 177Lu-FAP-2286 in Advanced Solid Tumors

Novartis Pharmaceuticals

NCT04939610

RECRUITING Phase 1 220 participants

A Study to Assess IPN01194 When Administered Alone in Adults With Advanced Solid Tumours

Ipsen

NCT06305247

RECRUITING Phase 1 219 participants

A Phase I Study of ROSE12 Alone and in Combination With Other Anti-tumor Agents in Patients With Solid Tumors

Chugai Pharmaceutical

NCT05907980

RECRUITING Phase 1 217 participants

A Study Investigating BGB-26808 Alone or in Combination With Tislelizumab in Participants With Advanced Solid Tumors

BeOne Medicines

NCT05981703

RECRUITING Phase 1 205 participants

A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

Terremoto Biosciences

NCT07109726

RECRUITING Phase 2 200 participants

Study of Induction PD-1 Blockade in Subjects With Locally Advanced Mismatch Repair Deficient Solid Tumors

Memorial Sloan Kettering Cancer Center

NCT04165772

RECRUITING Phase 1 200 participants

Safety and Preliminary Efficacy of OBT076 in Recurrent/Metastatic CD205+ Solid Tumors

Oxford BioTherapeutics

NCT04064359

RECRUITING Phase 1 195 participants

A Study of PT0511 in Participants With KRAS Mutated or Amplified Advanced Solid Tumors

PAQ Therapeutics

NCT07300150

RECRUITING Phase 1 191 participants

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

Tango Therapeutics

NCT06810544

RECRUITING NA 190 participants

Psychotherapy Intervention for Latinos With Advanced Cancer

Memorial Sloan Kettering Cancer Center

NCT04015609

RECRUITING Phase 1 188 participants

STC-15 as a Part of Combination Therapy With Toripalimab in Selected Advanced Cancers

STORM Therapeutics

NCT06975293

RECRUITING Phase 1 182 participants

A Study to Evaluate the Safety, Tolerability, and Efficacy of MORAb-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (FRα)-Targeting Antibody-drug Conjugate (ADC) in Participants With Selected Tumor Types

Eisai

NCT04300556

RECRUITING Phase 2 180 participants

Givastomig Combined With Nivolumab and Chemotherapy in Adults With CLDN18.2 Positive Metastatic Gastric Cancer (GIVA-2)

I-Mab Biopharma US Limited

NCT07432295

RECRUITING Phase 1 180 participants

Study of IDE397 in Participants With Solid Tumors Harboring MTAP Deletion

IDEAYA Biosciences

NCT04794699

RECRUITING Phase 1 161 participants

A Phase 1/2, Open-label, Multicenter, FIH Study to Evaluate Safety, Tolerability, PK and Anti-tumor Activity of YH42946

Yuhan Corporation

NCT06616766

RECRUITING NA 160 participants

Implementation of an Oral Chemotherapy Adherence Intervention

UNC Lineberger Comprehensive Cancer Center

NCT06989489

RECRUITING Phase 1 156 participants

First-in-human Study of CRB-601-01 to Treat Patients With Advanced Solid Tumor.

Corbus Pharmaceuticals

NCT06603844

RECRUITING Phase 1 150 participants

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

NiKang Therapeutics

NCT06586957

RECRUITING 150 participants

Liquid Biopsy-informed Precision Oncology Study to Evaluate Utility of Plasma Genomic Profiling for Therapy Selection

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT05585684

RECRUITING Phase 1 150 participants

Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer

Incyclix Bio

NCT05735080

RECRUITING Phase 1 150 participants

A First-in-Human Study of SON-DP in Participants With Relapsed/Refractory Intolerant to Standard of Care Therapies for Advanced/Metastatic Solid Tumors

Qurgen

NCT05989724

RECRUITING Phase 1 140 participants

FIH Trial of VERT-002 in Patients With Locally Advanced or Metastatic Solid Tumors With MET Alterations

Pierre Fabre Medicament

NCT06669117

RECRUITING Phase 1 140 participants

A Study of ZN-c3 in Patients With Ovarian Cancer

K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals

NCT04516447

RECRUITING Phase 1 140 participants

Study of TU2218 in Combination With KEYTRUDA®(Pembrolizumab) in Patients With Advanced Solid Tumors

TiumBio Co.

NCT05784688

RECRUITING Phase 1 128 participants

Phase Ib Study of CBP-1019 in Combination With FOLFOX +/- Bevacizumab, Pembrolizumab, or Enzalutamide for Metastatic TRPV6-overexpressing Solid Tumors of Epithelial Origin

M.D. Anderson Cancer Center

NCT06576037

RECRUITING NA 125 participants

DESCANSO, a Mental Health Intervention for Depression, Insomnia, and Fatigue Symptoms in Latino People With Cancer

Memorial Sloan Kettering Cancer Center

NCT07225088

RECRUITING 120 participants

Characterizing Sleep Among Long-term Survivors of Childhood Cancer

St. Jude Children's Research Hospital

NCT05480904

RECRUITING NA 120 participants

High Dose Re-Irradiation Utilizing Advanced Deformable Image Registration (DIR) and Individualized Organ At Risk (OAR) Dose Calculations With Organ Specific Toxicity Analysis

Medical College of Wisconsin

NCT05301101

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Phase Distribution

PhaseTrial count
Phase 1 150
Phase 2 15
Phase 3 1
Phase 4 3

Named interventions

Most-linked intervention names on Solid Tumor records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Nivolumab Drug
7 trials
Pembrolizumab Drug
5 trials
Gemcitabine Drug
4 trials
Leucovorin Drug
4 trials
Bevacizumab Drug
4 trials
Cyclophosphamide Drug
4 trials
Irinotecan Drug
3 trials
Cetuximab Drug
3 trials

US sites by state

Facility locations filed on Solid Tumor trials. A trial with sites in several states counts in each.

Texas 93 trials
California 72 trials
New York 67 trials
Florida 47 trials
Tennessee 42 trials
Massachusetts 38 trials
Michigan 36 trials
Arizona 36 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Solid Tumor page

197 registered trials, 104 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Solid Tumor condition card totals 197 registered trials; most-linked intervention Nivolumab; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.