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RECRUITING Phase 1

A Study of PYX-201 in Advanced Solid Tumors

NCT05720117 · View on ClinicalTrials.gov ↗

Study Summary

The primary objectives of this study are to determine the recommended dose(s) of PYX-201 for participants with recurrent/metastatic (R/M) solid tumors, and to determine the objective response rate (ORR) in participants treated with PYX-201 as a single agent.

Interventions

  • DRUG PYX-201

Study Locations (20)

Texas

  • NEXT Dallas — Dallas
  • The University of Texas MD Anderson Cancer Center — Houston
  • NEXT San Antonio — San Antonio

Massachusetts

  • Massachusetts General Hospital — Boston
  • Dana-Farber Cancer Institute — Boston

Brussels Capital

  • Institut Jules Bordet — Brussels
  • Cliniques Universitaires Saint-Luc — Brussels

Arizona

  • HonorHealth Research Institute — Scottsdale

California

  • Ronald Reagan UCLA Medical Center — Los Angeles

Colorado

  • SCRI - HealthOne Denver — Denver

Florida

  • SCRI - Florida Cancer Specialists — Sarasota

Georgia

  • Winship Cancer Institute, Emory University — Atlanta

Trial Details

FieldValue
Enrollment Target 330 participants
Start Date 2023-03-14
Est. Completion 2027-05
Phase Phase 1

Sponsor

Pyxis Oncology

3 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05720117

The ClinicalTrials.gov registry entry for NCT05720117 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 330 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Pyxis Oncology, which has 3 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Solid Tumor appearing as the primary indexed condition, and to 1 intervention — of which PYX-201 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05720117 reports 20 study locations spanning 16 distinct geographic areas — top geographies include Texas, Massachusetts, Brussels Capital. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05720117 about?

NCT05720117 is a clinical study titled "A Study of PYX-201 in Advanced Solid Tumors". The primary objectives of this study are to determine the recommended dose(s) of PYX-201 for participants with recurrent/metastatic (R/M) solid tumors, and to determine the objective response rate (ORR) in participants treated with PYX-201 as a single agent.

What is the current status of trial NCT05720117?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 330 participants. The study started on 2023-03-14. Estimated completion is 2027-05.

What conditions does trial NCT05720117 study?

This clinical trial studies the following conditions: Solid Tumor, Advanced Solid Tumor. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05720117?

The interventions under investigation include: PYX-201 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05720117?

This trial is sponsored by Pyxis Oncology, which has 3 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05720117 being conducted?

This trial has 20 study locations across Arizona, California, Colorado, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial