Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

RECRUITING Phase 1

Study of TU2218 in Combination With KEYTRUDA®(Pembrolizumab) in Patients With Advanced Solid Tumors

NCT05784688 · View on ClinicalTrials.gov ↗

Study Summary

This study consists of phase 1b and 2a to evaluate safety, Pharmacokinetics, and efficacy of TU2218 in combination with Pembrolizumab in patients with advanced solid tumors.

Interventions

  • DRUG TU2218 + KEYTRUDA® (Pembrolizumab)

Study Locations (11)

Other

  • CHA University Bundang Medical Center — Seongnam
  • Seoul National University Bundang Hospital — Seongnam
  • Asan Medical Center — Seoul
  • Samsung Medical Center — Seoul
  • Seoul National University Hospital — Seoul
  • Severance Hospital — Seoul
  • The Catholic University of Korea Seoul St. Mary Hospital — Seoul
  • The Catholic University of Korea St. Vincent's Hospital — Suwon

Texas

  • NEXT Oncology — San Antonio
  • Hope Cancer Center — Tyler

Washington

  • Medical Oncology — Spokane

Trial Details

FieldValue
Enrollment Target 140 participants
Start Date 2023-03-10
Est. Completion 2028-12
Phase Phase 1

Sponsor

TiumBio Co.

33 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05784688

The ClinicalTrials.gov registry entry for NCT05784688 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 140 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is TiumBio Co., which has 33 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 4 conditions, with Colorectal Cancer appearing as the primary indexed condition, and to 1 intervention — of which TU2218 + KEYTRUDA® (Pembrolizumab) is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05784688 reports 11 study locations spanning 3 distinct geographic areas — top geographies include Other, Texas, Washington. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05784688 about?

NCT05784688 is a clinical study titled "Study of TU2218 in Combination With KEYTRUDA®(Pembrolizumab) in Patients With Advanced Solid Tumors". This study consists of phase 1b and 2a to evaluate safety, Pharmacokinetics, and efficacy of TU2218 in combination with Pembrolizumab in patients with advanced solid tumors.

What is the current status of trial NCT05784688?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 140 participants. The study started on 2023-03-10. Estimated completion is 2028-12.

What conditions does trial NCT05784688 study?

This clinical trial studies the following conditions: Colorectal Cancer, Solid Tumor, Head and Neck Squamous Cell Carcinoma, Biliary Tract Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05784688?

The interventions under investigation include: TU2218 + KEYTRUDA® (Pembrolizumab) (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05784688?

This trial is sponsored by TiumBio Co., which has 33 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05784688 being conducted?

This trial has 11 study locations across Texas, Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial