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NCT05301101 · ClinicalTrials.gov registry record · NA

High Dose Re-Irradiation Utilizing Advanced Deformable Image Registration (DIR) and Individualized Organ At Risk (OAR) Dose Calculations With Organ Specific Toxicity Analysis

A NA study of Solid Tumor, sponsored by Medical College of Wisconsin.

Recruiting
Registry status
NA
Development phase
120
Enrollment target
1
Study location

NCT05301101: Recruiting NA study of Solid Tumor, sponsored by Medical College of Wisconsin.

NCT05301101 is a NA study of Solid Tumor that is actively recruiting participants, run by Medical College of Wisconsin. The registered enrollment target is 120 participants, below the 221-participant average among 196 other Solid Tumor trials with a reported enrollment target (46% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05301101, a NA study of Solid Tumor, is actively recruiting participants, sponsored by Medical College of Wisconsin.

RECRUITING
Registry status
NA
Development phase
120 participants
Enrollment target
1
Study location

Study Summary

This trial applies a uniform approach to re-irradiation for planning and diagnostic image fusion, dose summation, dose calculations, and follow up for tumor control and detailed toxicity analysis of serial Organs At Risk (OARs). Serial organs include named arteries and nerves, spinal cord, and gastrointestinal tract.

Primary Outcome

The number of patients with organ-specific grade 3 toxicity in patients undergoing high-dose re-irradiation. Common Terminology Criteria for Adverse Events (CTCAE) v.5.0 will be used to define the grade.

Conditions Studied

Interventions

  • RADIATION Re-irradiation

Study Locations (1)

Wisconsin

  • Froedtert Hospital - Milwaukee

Trial Details

FieldValue
Enrollment Target 120 participants
Start Date 2022-06-13
Est. Completion 2028-07
Phase NA
Medical College of Wisconsin

447 total trials

What NCT05301101 shows while recruiting

NCT05301101 is an interventional study that assigns participants to a tested intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap, below the 221-participant average among 196 other Solid Tumor trials with a reported enrollment target (46% lower).

The record links to 1 condition, with Solid Tumor appearing as the primary indexed condition, and to 1 intervention - of which Re-irradiation is the first listed.

NCT05301101 reports a single indexed study location in Wisconsin.

Frequently Asked Questions

What is clinical trial NCT05301101 about?

NCT05301101 is a clinical study titled "High Dose Re-Irradiation Utilizing Advanced Deformable Image Registration (DIR) and Individualized Organ At Risk (OAR) Dose Calculations With Organ Specific Toxicity Analysis". This trial applies a uniform approach to re-irradiation for planning and diagnostic image fusion, dose summation, dose calculations, and follow up for tumor control and detailed toxicity analysis of serial Organs At Risk (OARs). Serial organs include named arteries and nerves, spinal cord, and gastr...

What is the current status of trial NCT05301101?

This trial is currently recruiting. It is a NA study. The enrollment target is 120 participants. The study started on 2022-06-13. Estimated completion is 2028-07.

What conditions does trial NCT05301101 study?

This clinical trial studies the following conditions: Solid Tumor.

What interventions are being tested in trial NCT05301101?

The interventions under investigation include: Re-irradiation (RADIATION).

Who is sponsoring clinical trial NCT05301101?

This trial is sponsored by Medical College of Wisconsin, which has 447 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05301101 being conducted?

This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Solid Tumor

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05301101's enrollment target sits among peer trials

120 72nd of 196 higher than 122 of 196 other Solid Tumor trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Solid Tumor trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05301101, the US trial registry maintained by the National Library of Medicine. NCT05301101 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.