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ClinicalTrials.gov 275 recruiting now early-phase tilt #4 of 28,963 conditions

Prostate Cancer: early-phase trial registry

275 of 749 indexed Prostate Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #4 of 28,963 conditions by registered trial count.

749 US clinical trials · 275 currently recruiting · #4 of 28,963 conditions by registered trial count

Prostate Cancer: 749 US clinical trials tracked, 275 recruiting.

Prostate Cancer is the subject of 749 registered US clinical trials on ClinicalTrials.gov, 275 of them currently open to new participants. 75 are in Phase 3-4 (later-stage) and 344 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 53 of these trials.

Open enrollment, early-phase tilt

Prostate Cancer has 749 registered US clinical trials, 275 of them open to new participants right now, about 37% of the total.

275
recruiting participants now
37%
of trials open to enrollment
75
in Phase 3-4 (later-stage)
53
top sponsor: Memorial Sloan Kettering Cancer Center

Corpus placement: #4 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.

Key findings

What ClinicalTrials.gov does not surface for Prostate Cancer on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.

  1. Prostate Cancer recruits in line with its size-band peers.

    275 of 749 indexed trials (36.7%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Prostate Cancer trials is spread across many organizations.

    Memorial Sloan Kettering Cancer Center accounts for 53 of 749 trials (7.1%). 283 distinct sponsors appear on at least one study for this condition label.

  3. Typical Prostate Cancer enrolment sits around 82 participants.

    Median target enrolment is 82 among the 736 trials that report a genuine target (sentinel values excluded). 389 of those (52.9%) plan for fewer than 100 participants.

  4. Prostate Cancer research is mostly interventional.

    628 interventional and 121 observational studies make up this index (83.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 1156Phase 2188Phase 362Phase 413

Open and recent trials

749 total, page 2 of 15

RECRUITING Phase 1 479 participants

Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer

Amgen

NCT04221542

RECRUITING NA 466 participants

Connect2Care: Prostate Cancer Education and Screenings for African American Men

University of Oklahoma

NCT07055165

RECRUITING Phase 2 464 participants

Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer

VA Office of Research and Development

NCT04787744

RECRUITING 462 participants

Active Surveillance for Cancer of the Prostate (ASCaP)

Jonsson Comprehensive Cancer Center

NCT00949819

RECRUITING NA 445 participants

Developing New Educational Materials About Genetic Testing for a Diverse Group of Cancer Patients

Memorial Sloan Kettering Cancer Center

NCT04751435

RECRUITING Phase 2 443 participants

Open-label Study Comparing AAA817 Versus Standard of Care in the Treatment of Previously Treated PSMA-positive mCRPC Adults Who Have Disease Progressed on or After [177Lu]Lu-PSMA Targeted Therapy

Novartis Pharmaceuticals

NCT06780670

RECRUITING Phase 3 439 participants

Copper Cu 64 PSMA I&T PET Imaging in Men With Newly Diagnosed Prostate Cancer

Curium US

NCT06235151

RECRUITING 420 participants

Navigator-Assisted Hypofractionation (NAVAH) on Radiation Therapy Completion in Breast Cancer and Prostate Cancer

University of Oklahoma

NCT07014618

RECRUITING 400 participants

The Effect of IBD Flares on Serum PSA

Northwestern University

NCT03558048

RECRUITING 400 participants

Prostate Cancer Genetic Risk Evaluation and Screening Study

Massachusetts General Hospital

NCT05129605

RECRUITING NA 397 participants

Stereotactic Magnetic Resonance Guided Radiation Therapy

Dana-Farber Cancer Institute

NCT04115254

RECRUITING Phase 2 392 participants

ADT and SBRT vs SBRT Alone for Unfavorable Intermediate Risk Prostate Cancer

NYU Langone Health

NCT06397703

RECRUITING Phase 3 383 participants

Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy

Clarity Pharmaceuticals

NCT06056830

RECRUITING 350 participants

Prospective Monitoring of Subjects With Biochemically Recurrent Prostate Cancer Using 18FDCFPyL

National Cancer Institute (NCI)

NCT05588128

RECRUITING 350 participants

PRISM: Patient Experiences With PET Imaging in Prostate Cancer

Yale University

NCT06523777

RECRUITING Phase 2 315 participants

Genomic Biomarker-Selected Umbrella Neoadjuvant Study for High Risk Localized Prostate Cancer

University of British Columbia

NCT04812366

RECRUITING NA 306 participants

Precise Oncology Interventions in Nutrition and Training (OnPoint)

University of Miami

NCT06534918

RECRUITING Phase 3 300 participants

Robotic Opioid-free Prostatectomy Enhanced Strategy (ROPES)

Brigham and Women's Hospital

NCT07427043

RECRUITING 300 participants

Imaging Studies to Check the Local Response of Prostate Cancer to Radiation Therapy

National Cancer Institute (NCI)

NCT01834001

RECRUITING Phase 1 300 participants

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

PMV Pharmaceuticals

NCT04585750

RECRUITING 300 participants

Clinical Outcomes in Prostate Cancer Patients Undergoing HIFU Ablation

NYU Langone Health

NCT07203482

RECRUITING NA 300 participants

[18F]-Fluoro-2-Deoxy-D-Glucose and -[18F] Dihydro-Testosterone Pet Imaging in Patients With Progressive Prostate Cancer

Memorial Sloan Kettering Cancer Center

NCT00588185

RECRUITING Phase 3 291 participants

Trial of Curcumin to Prevent Progression of Low-risk Prostate Cancer Under Active Surveillance

University of Texas Southwestern Medical Center

NCT03769766

RECRUITING Phase 2 288 participants

PSMA-PET to Guide Prostatectomy

Five Eleven Pharma

NCT05381103

RECRUITING NA 283 participants

RCT of NLP-Based Feedback for Improving SDM in Men With Localized Prostate Cancer

Cedars-Sinai Medical Center

NCT06856694

RECRUITING NA 276 participants

Single-Port Transvesical Partial Prostatectomy Versus High Intensity Focused Ultrasound

Case Comprehensive Cancer Center

NCT05610852

RECRUITING Phase 1 272 participants

Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)

Janux Therapeutics

NCT05519449

RECRUITING NA 260 participants

DISCO: A Patient Intervention to Reduce the Financial Burden of Cancer

Lauren Hamel

NCT04766190

RECRUITING Phase 1 258 participants

A Study to Examine the Safety of Different Doses of BG-68501 Given to Participants With Advanced-Stage Tumors

BeiGene

NCT06257264

RECRUITING NA 258 participants

Diagnostic Performance Of Non-Endorectal Coil Multiparametric Magnetic Resonance Imaging Of Prostate With Flexible AIR Coil (DoNEMAC Study)

M.D. Anderson Cancer Center

NCT05043012

RECRUITING Phase 1 252 participants

Open-Label Study of Pocenbrodib Alone and in Combination With Abiraterone Acetate, Olaparib, or 177Lu-PSMA-617

Pathos AI

NCT06785636

RECRUITING NA 250 participants

Patient Decision-making About Precision Oncology in Veterans With Advanced Prostate Cancer

University of California, San Francisco

NCT05396872

RECRUITING NA 248 participants

Using a mHealth App to Improve Quality-of-Life Outcomes in Black Prostate Cancer Survivors

University of Oklahoma

NCT06651359

RECRUITING Phase 4 240 participants

Preop Laxatives in Robotic Urologic Surgery

Chad R. Tracy

NCT05805436

RECRUITING 225 participants

Outcomes of Focal Ablation for Prostate Cancer

University of Texas Southwestern Medical Center

NCT05478694

RECRUITING NA 225 participants

Prostate Cancer IMAGing IN Early Detection (IMAGINED Trial)

University of California, San Diego

NCT05882253

RECRUITING NA 224 participants

Helping Men Adhere to Sexual Rehabilitation Following Prostate Cancer Surgery

Memorial Sloan Kettering Cancer Center

NCT02706561

RECRUITING 222 participants

MRI And GPS Informing Choices for Prostate Cancer Treatment (MAGIC)

Northwestern University

NCT05424783

RECRUITING Phase 1 220 participants

Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors

MOMA Therapeutics

NCT06545942

RECRUITING Phase 3 220 participants

64Cu-SAR-bisPSMA Positron Emission Tomography: A Phase 3 Study of Participants With Biochemical Recurrence of Prostate Cancer

Clarity Pharmaceuticals

NCT06970847

RECRUITING NA 220 participants

Designing Visual Tools to Enhance Cancer Surgeon Decision-making

UNC Lineberger Comprehensive Cancer Center

NCT06965192

RECRUITING Phase 2 219 participants

Trial of Neoadjuvant Enoblituzumab vs SOC in Men With High-Risk Localized Prostate Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT06014255

RECRUITING Phase 2 218 participants

A Phase 2 Study to Evaluate the Effects of ASP5541 in Participants With Prostate Cancer

Astellas Pharma Global Development

NCT07005154

RECRUITING Phase 1 216 participants

A Study of PARG Inhibitor IDE161 in Participants With Advanced Solid Tumors

IDEAYA Biosciences

NCT05787587

RECRUITING Phase 2 215 participants

A Study of Stereotactic Body Radiation Therapy (SBRT) Without Androgen Deprivation Therapy (ADT) in People With Unfavorable Intermediate-Risk Prostate Cancer

Memorial Sloan Kettering Cancer Center

NCT05169970

RECRUITING NA 210 participants

Improving Health Literacy in African-American Prostate Cancer Patients

Emory University

NCT03322891

RECRUITING NA 210 participants

Micro-UltraSound In Cancer - Active Surveillance

University of Alberta

NCT05558241

RECRUITING NA 208 participants

Virtual Reality Headset and/or Aromatherapy for Patients Undergoing a Transperineal Prostate Biopsy

University of Pittsburgh

NCT06296147

RECRUITING 200 participants

Circulating Tumor Cell Analysis in Patients With Localized Prostate Cancer Undergoing Prostatectomy

Massachusetts General Hospital

NCT01961713

RECRUITING Phase 1 200 participants

A Study to Evaluate the Safety, Pharmacokinetics and Efficacy of TJ101 in Patients With Advanced/Metastatic Solid Tumors

Phrontline Biopharma

NCT07181473

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Phase Distribution

PhaseTrial count
Phase 1 156
Phase 2 188
Phase 3 62
Phase 4 13

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What is open for Prostate Cancer right now

275 recruiting of 749 indexed (37% open).

Phase mix: 75 late (III/IV) vs 344 early (I/II) (early-phase heavy).

Top sponsor: Memorial Sloan Kettering Cancer Center (53 trials), 9 others listed. 50 shown below, recruiting first. #4 of 28,963 conditions by registered trial count.

How open-enrollment share is computed

Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.

Frequently Asked Questions

How many clinical trials are there for Prostate Cancer?

PlainTrial tracks 749 US clinical trials for Prostate Cancer, of which 275 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Prostate Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.