Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

2026 data Public-data reference. official source

Chronic Disease

Open-data reference.

49 US clinical trials · 18 currently recruiting

Active & Recent Trials

RECRUITING 2,000,000 participants

Observational Pharmaco-Epidemiology Research & Analysis

Epividian

NCT03813862

RECRUITING 50,000 participants

RIVER At Home Ketamine Protocols

RIVER Foundation

NCT06070766

RECRUITING NA 5,000 participants

Evaluation of AI Cost Prediction Model to Enroll Patients in Complex Care Management Program

University of California, Los Angeles

NCT06916247

RECRUITING NA 795 participants

CHIME: Comparing Health Interventions for Maternal Equity

Stanford University

NCT06724172

RECRUITING NA 600 participants

Comparative Effectiveness of IIMR Versus CDSMP

Dartmouth-Hitchcock Medical Center

NCT03966872

RECRUITING NA 500 participants

Improving the Collaborative Health of Minority COVID-19 Survivor and Carepartner Dyads

University of South Carolina

NCT05370014

RECRUITING 500 participants

AIMS Medical Outcomes Study

Advanced Integrative Medical Science Institute

NCT04512755

RECRUITING 500 participants

Ketamine Treatment Plans for Chronic Conditions

RIVER Foundation

NCT06038409

RECRUITING NA 460 participants

Housing, Environment, And Living Conditions for Transformed Health

University of Alabama at Birmingham

NCT06925373

RECRUITING NA 300 participants

Click & Pick Study

University of Pennsylvania

NCT07422922

RECRUITING NA 300 participants

Training Community Members to be Coaches to Deliver the HealthyLifetime Program

University of Michigan

NCT06616246

RECRUITING 300 participants

Expanded Population Health Model Evaluation

Baylor Research Institute

NCT06044831

RECRUITING NA 160 participants

Effects of Personalized Exercise Prescriptions Through Mobile Health on Physical Activity and Health Outcomes in the Cancer Survivors

The University of Tennessee, Knoxville

NCT06840028

RECRUITING 150 participants

Barriers to Vegetarian Diets

University of Maryland, Baltimore

NCT07075653

RECRUITING 100 participants

Biospecimen Analysis in Detecting Chemical Concentrations in Patients With Chronic or Infectious Diseases Receiving Meditations

City of Hope Medical Center

NCT04160429

RECRUITING NA 70 participants

Families Implementing Good Health Traditions for Life

Morehouse School of Medicine

NCT07441655

RECRUITING 20 participants

Feasibility of Remote Activity Assessment and PRO Collection Among Transgender Cancer Survivors

Cedars-Sinai Medical Center

NCT05391217

RECRUITING NA 8 participants

Supporting Resilience Among Re-entered Seniors

University of Louisville

NCT06276452

ACTIVE NOT RECRUITING 50,000 participants

The MURDOCK Study Registry and Biorepository Horizon 1.5

Duke University

NCT01708408

ACTIVE NOT RECRUITING 50,000 participants

Virta Health Registry

Virta Health

NCT03474692

ACTIVE NOT RECRUITING 100 participants

Verily Clinical Study Watch Analytical Validation Study

Verily Life Sciences

NCT05534477

ACTIVE NOT RECRUITING Phase 4 30 participants

Dupixent Study for Alternate Administration

Madigan Army Medical Center

NCT06750471

COMPLETED 1,939,848 participants

Post Affordable Care Act Evaluation

Oregon Health and Science University

NCT02657499

COMPLETED NA 174,120 participants

Deep Dive Randomized Control Trial

Health Dialog

NCT00793260

COMPLETED 28,813 participants

Evaluating the Navajo Community Outreach and Patient Empowerment (COPE) Program

Brigham and Women's Hospital

NCT03326206

COMPLETED 7,905 participants

Learning and Relationships in Primary Care

VA Office of Research and Development

NCT00657696

COMPLETED NA 2,512 participants

Project to Improve Communication About Serious Illness--Hospital Study: Pragmatic Trial (Trial 1)

University of Washington

NCT04281784

COMPLETED NA 1,170 participants

A National Study of the Chronic Disease Self-Management Program

Stanford University

NCT01845857

COMPLETED NA 422 participants

An Integrated Telemedicine-Home Visitation Program to Increase Outcomes for Children With Medical Complexity

The University of Texas Health Science Center, Houston

NCT03590509

COMPLETED 419 participants

Advance Care Planning GuideTailored for Primary Care Patients

Ohio State University

NCT03906773

COMPLETED NA 300 participants

Comprehensive Care of Children With Medical Complexity

Seton Healthcare Family

NCT01834456

COMPLETED Phase 2 297 participants

Healthier Living Canada

Stanford University

NCT01047514

COMPLETED NA 263 participants

Home Based Care Transitions Tailored by Cognition and Patient Activation

University of Nebraska

NCT02045147

COMPLETED NA 251 participants

Social Risk Score, Clinical Decision Support Tool and Closed Loop Referral for Social Risk Screen and Referral

Johns Hopkins University

NCT05574699

COMPLETED NA 211 participants

Improving Chronic Illness Management With the Apsaalooke Nation: The Baa Nnilah Project

Montana State University

NCT03036189

COMPLETED NA 134 participants

Nature and Health: How Does Lifestyle and Environment Affect Health and Wellness

Stanford University

NCT06001697

COMPLETED NA 111 participants

Incorporating Patient Capacity Into the Clinical Landscape

Mayo Clinic

NCT02390570

COMPLETED NA 88 participants

A Pharmacist-led Transitions of Care Program

Auburn University

NCT04556786

COMPLETED NA 80 participants

Use of a DeskCycle to Reduce Sedentary Behavior During the Workday

Kent State University

NCT05412797

COMPLETED NA 80 participants

Rural Chronic Disease Risk Reduction

Florida State University

NCT05611580

COMPLETED NA 75 participants

The Vegetable Dose Response Study: Effects of Consumption on Inflammation and Oxidative Stress

University of Arizona

NCT01454674

COMPLETED Phase 3 69 participants

Comparative Trial of Entecavir Versus Adefovir in the Treatment of Chronic Hepatitis B Infection

Bristol-Myers Squibb

NCT00096785

COMPLETED NA 47 participants

Assessment of Plant-based Program Using Shared Medical Appointment

The University of Texas Health Science Center at San Antonio

NCT05889715

COMPLETED NA 46 participants

Virtual Lifestyle Medicine Comparative Effectiveness Research

Ohio University

NCT03731481

COMPLETED NA 37 participants

Lifestyle Education and Nutrition Demonstration

The Cleveland Clinic

NCT03095768

COMPLETED NA 30 participants

Prevention of Dichloroacetate Toxicity

University of Florida

NCT00031161

COMPLETED NA 29 participants

Team-Based Delivery of Care in Outpatient Settings

Mayo Clinic

NCT03062670

COMPLETED NA 16 participants

Feasibility of Ripple Health Smart Pill Caps in Clinical Settings

Manan Shukla

NCT05192928

COMPLETED 9 participants

Formative Evaluation in Implementation Research: Guideline Development

VA Office of Research and Development

NCT00683540

Phase Distribution

PhaseTrial count
Phase 2 1
Phase 3 1
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Chronic Disease Trial Landscape

ClinicalTrials.gov lists 49 US studies indexed under Chronic Disease, and 18 of those are currently open to recruitment — roughly 37% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Chronic Disease shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 1 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Chronic Disease is led by Stanford University with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 49 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Chronic Disease?

PlainTrial tracks 49 US clinical trials for Chronic Disease, of which 18 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Chronic Disease?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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