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ClinicalTrials.gov 275 recruiting now early-phase tilt #4 of 28,963 conditions

Prostate Cancer: early-phase trial registry

275 of 749 indexed Prostate Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #4 of 28,963 conditions by registered trial count.

749 US clinical trials · 275 currently recruiting · #4 of 28,963 conditions by registered trial count

Prostate Cancer: 749 US clinical trials tracked, 275 recruiting.

Prostate Cancer is the subject of 749 registered US clinical trials on ClinicalTrials.gov, 275 of them currently open to new participants. 75 are in Phase 3-4 (later-stage) and 344 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 53 of these trials.

Open enrollment, early-phase tilt

Prostate Cancer has 749 registered US clinical trials, 275 of them open to new participants right now, about 37% of the total.

275
recruiting participants now
37%
of trials open to enrollment
75
in Phase 3-4 (later-stage)
53
top sponsor: Memorial Sloan Kettering Cancer Center

Corpus placement: #4 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.

Key findings

What ClinicalTrials.gov does not surface for Prostate Cancer on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.

  1. Prostate Cancer recruits in line with its size-band peers.

    275 of 749 indexed trials (36.7%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Prostate Cancer trials is spread across many organizations.

    Memorial Sloan Kettering Cancer Center accounts for 53 of 749 trials (7.1%). 283 distinct sponsors appear on at least one study for this condition label.

  3. Typical Prostate Cancer enrolment sits around 82 participants.

    Median target enrolment is 82 among the 736 trials that report a genuine target (sentinel values excluded). 389 of those (52.9%) plan for fewer than 100 participants.

  4. Prostate Cancer research is mostly interventional.

    628 interventional and 121 observational studies make up this index (83.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 1156Phase 2188Phase 362Phase 413

Open and recent trials

749 total, page 3 of 15

RECRUITING 200 participants

Building on Trust: Navigating Preventive Lung, Breast, and Prostate Cancer Screenings at Community Resource Spots

AdventHealth

NCT07231159

RECRUITING 200 participants

Microendoscopic EI Sensing for Real-time Intraoperative Surgical Margin Assessment

Ryan J. Halter

NCT06039085

RECRUITING 200 participants

Ablative Therapy in the Management of Prostate Cancer

Weill Medical College of Cornell University

NCT03492424

RECRUITING Phase 2 200 participants

MDRT in Prostate Cancer Treated With Long-term Androgen Deprivation Therapy in the STAMPEDE Trial (METANOVA)

Case Comprehensive Cancer Center

NCT06150417

RECRUITING Phase 3 200 participants

Vascular Optimized Radiotherapy Tuned to Critical Structures for Erectile Function Using High-Precision X-Ray Treatment

Jonsson Comprehensive Cancer Center

NCT07293585

RECRUITING NA 200 participants

Evaluation of Prostate Specific Membrane Antigen Positron Emission Tomography-Computed Tomography in Active Surveillance for Prostate CancEr

Weill Medical College of Cornell University

NCT05948657

RECRUITING 200 participants

Prostate Tissue BioBank

Abramson Cancer Center at Penn Medicine

NCT06659614

RECRUITING Phase 4 198 participants

Anti-inflammatory Drugs and Serum Prostate-Specific Antigen Test

Albany Medical College

NCT05629494

RECRUITING Phase 3 196 participants

SAFE Nerve Sparing Guided by Micro-ultrasound (MUS)

Icahn School of Medicine at Mount Sinai

NCT06945315

RECRUITING NA 194 participants

AVI Didactic Experience for Latinx Patient Treatment Adherence and Non-English Speaker Trial Enrollment Study in Rad Onc

Columbia University

NCT05351424

RECRUITING Phase 3 192 participants

Hypo-fractionated Radiation Therapy With or Without Androgen Suppression for Intermediate Risk Prostate Cancer

Proton Collaborative Group

NCT01492972

RECRUITING Phase 2 184 participants

PyL in Patients With High Risk and Biochemically Recurrent Prostate Cancer

Hoag Memorial Hospital Presbyterian

NCT04700332

RECRUITING NA 180 participants

MRI Risk Maps for Prostate Cancer Diagnosis Using Targeted Biopsy

University of Chicago

NCT05710380

RECRUITING 180 participants

Older Men's Decision Making About Active Surveillance for Prostate Cancer - Aim 3: Decision Aid Efficacy Testing

M.D. Anderson Cancer Center

NCT06785441

RECRUITING NA 180 participants

CV CARE: CardioVascular Care in PC Patients

Dana-Farber Cancer Institute

NCT06202820

RECRUITING Phase 1 174 participants

A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer

Astellas Pharma Global Development

NCT04729114

RECRUITING NA 167 participants

TRUEBEAM Stereotactic Body Radiotherapy for Localized Prostate Cancer

Linda Chan, MD

NCT04552509

RECRUITING Phase 2 161 participants

Magnetic Resonance (MR) Imaging With Hyperpolarized 13C-Pyruvate +/- 13C,15N-Urea in Patients With Prostate Cancer

Robert Bok, MD, PhD

NCT06391034

RECRUITING NA 155 participants

Study to Assess the Feasibility of Stopping Prostate Cancer Treatment Early in Elderly Patients

University of Chicago

NCT06824818

RECRUITING NA 150 participants

SBRT Boost for Unfavorable Prostate Cancer'

MemorialCare Health System

NCT02016248

RECRUITING NA 150 participants

Locally Ablative TherapY in Oligo-ProgressiVe GEnitourinary TumoRs (LAYOVER)

University of California, Davis

NCT06101290

RECRUITING NA 150 participants

Investigation of Impact of AI on Prostate Cancer Workflow

Case Comprehensive Cancer Center

NCT07084779

RECRUITING NA 150 participants

Sacral Neuromodulation for Male Overactive Bladder (MOAB)

Axonics

NCT06511141

RECRUITING Phase 2 150 participants

Image-guided, Tumor-focused Radiotherapy Treatment in Intermediate and High-risk Prostate Cancer

University of California, San Diego

NCT06990542

RECRUITING Phase 4 150 participants

Gadopiclenol in Contrast Enhanced MRI of the Prostate

Columbia University

NCT06226129

RECRUITING 150 participants

Characterizing the Genomic Landscape of Prostate Cancer in Native American Populations (NAT-Geno)

University of Oklahoma

NCT06960798

RECRUITING NA 149 participants

Serial MRI Scans During Radiation Therapy

Dana-Farber Cancer Institute

NCT04188535

RECRUITING 144 participants

Collection and Measurement of Biomarkers in Prostate Cancer Radiotherapy Patients

University of Miami

NCT02997709

RECRUITING Phase 2 140 participants

Intensive Cholesterol-Lowering and CD8+ T Cells in Prostate Cancer

Cedars-Sinai Medical Center

NCT06437574

RECRUITING Phase 2 136 participants

Post-prostatectomy Radiation Therapy--Moderate Versus Ultra-hypofractionated (Also Known as Stereotactic Body Radiation Therapy [SBRT])

University of Michigan Rogel Cancer Center

NCT05038332

RECRUITING Phase 2 134 participants

Telehealth Exercise Program Evaluating Fatigue and Physical Function in Rural Cancer Survivors

University of Colorado, Denver

NCT07001241

RECRUITING NA 132 participants

Daily Adaptive Radiation Therapy Using an Individualized Approach for Prostate Cancer

Varian, a Siemens Healthineers Company

NCT05804318

RECRUITING NA 132 participants

Effect of Text Message Reminders on M-ISI Score After Prostate Surgery

University of Rochester

NCT07071207

RECRUITING Phase 2 130 participants

The University of Miami Adapt (UAdapt) Trial

University of Miami

NCT06111313

RECRUITING NA 130 participants

A Study of Mental Health Care in People With Cancer

Memorial Sloan Kettering Cancer Center

NCT06037954

RECRUITING Phase 2 130 participants

Evaluation of Response to Abiraterone/Prednisone by Race/Ethnicity and Other Factors in Metastatic Hormone Naive Prostate Cancer

Martha Mims

NCT03833921

RECRUITING 125 participants

Mechanisms of Resistance to PSMA Radioligand Therapy

University of California, San Francisco

NCT05435495

RECRUITING Phase 2 122 participants

TERPS Trial for de Novo Oligometastic Prostate Cancer

University of Maryland, Baltimore

NCT05223803

RECRUITING Phase 1 122 participants

A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies

AtlasMedx, Incorporated

NCT04503265

RECRUITING Phase 3 120 participants

PROSTATE-IQ: Parallel RandOmized STudy of Personalized Apalutamide Treatment and Evaluation to Improve Quality of Life in Post-Operative Radiation With Androgen Axis Suppression. A Phase III Multi-center Study for Men With Detectable PSA After Prostatectomy for Prostate Cancer.

M.D. Anderson Cancer Center

NCT06274047

RECRUITING Phase 1 120 participants

A Study to Investigate the Biological Effects of Saruparib (AZD5305), Darolutamide, and in Combination in Men With Newly Diagnosed Prostate Cancer.

AstraZeneca

NCT05938270

RECRUITING Phase 1 120 participants

A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

858 Therapeutics

NCT06395519

RECRUITING 120 participants

ARCTIC: Liquid Biomarkers in the Prospective Androgen Receptor Signaling Inhibitors (ARSI) Resistance Clinical Trials

Duke University

NCT06141993

RECRUITING Phase 2 120 participants

Diagnostic Utility of rhPSMA-7.3 (18F) PET/CT in Men With Prostate Cancer on Active Surveillance

Icahn School of Medicine at Mount Sinai

NCT07285057

RECRUITING 120 participants

Geriatric Assessment and Technology Evaluation in Prostate Cancer

University of Chicago

NCT06215508

RECRUITING Phase 3 113 participants

Role of rhPSMA-7.3 PET/CT Imaging in Men With High-Risk Prostate Cancer Following Conventional Imaging and Associated Changes in Medical Management

MidLantic Urology

NCT05799248

RECRUITING Phase 1 110 participants

A Study to Evaluate Safety, Efficacy, and Pharmacokinetics in Participants With Advanced Solid Tumors

Eutilex

NCT04903873

RECRUITING Phase 2 110 participants

RecoverPC: Relugolix vs GnRH Agonist in Quality of Life

Dana-Farber Cancer Institute

NCT05765500

RECRUITING 100 participants

HIFU for Focal Ablation of Prostate Tissue: An Observational Study

University of California, Los Angeles

NCT03620786

RECRUITING Phase 1 100 participants

Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma

Nammi Therapeutics

NCT06582017

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Phase Distribution

PhaseTrial count
Phase 1 156
Phase 2 188
Phase 3 62
Phase 4 13

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What is open for Prostate Cancer right now

275 recruiting of 749 indexed (37% open).

Phase mix: 75 late (III/IV) vs 344 early (I/II) (early-phase heavy).

Top sponsor: Memorial Sloan Kettering Cancer Center (53 trials), 9 others listed. 50 shown below, recruiting first. #4 of 28,963 conditions by registered trial count.

How open-enrollment share is computed

Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.

Frequently Asked Questions

How many clinical trials are there for Prostate Cancer?

PlainTrial tracks 749 US clinical trials for Prostate Cancer, of which 275 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Prostate Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.