Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT05558241 · ClinicalTrials.gov registry record · NA

Micro-UltraSound In Cancer - Active Surveillance

A NA study of Prostate Cancer, sponsored by University of Alberta.

Recruiting
Registry status
NA
Development phase
210
Enrollment target
5
Study locations

NCT05558241: Recruiting NA study of Prostate Cancer, sponsored by University of Alberta.

NCT05558241 is a NA study of Prostate Cancer that is actively recruiting participants, run by University of Alberta. The registered enrollment target is 210 participants, below the 608-participant average among 735 other Prostate Cancer trials with a reported enrollment target (65% lower). The trial reports 5 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT05558241, a NA study of Prostate Cancer, is actively recruiting participants, sponsored by University of Alberta.

RECRUITING
Registry status
NA
Development phase
210 participants
Enrollment target
5
Study locations

Study Summary

This study will compare the two imaging modalities (MRI and micro-ultrasound) during Active Surveillance of prostate cancer (PCa). Progression to clinically significant PCa will be assessed by first taking micro-US targeted samples (while blinded to MRI results), followed by MRI targeted samples, finishing with 12 systematic biopsy cores. The primary goal is to compare microUS to MRI for the detection of ≥GG2 PCa at confirmatory biopsy. This study will also collect blood samples from participants to be used for future biomarker studies.

Primary Outcome

The primary outcome will be detection of ≥Grade Group 2 by each biopsy, technique in combination with the systematic biopsy.

Conditions Studied

Interventions

  • DEVICE High-resolution micro-ultrasound

Study Locations (5)

Alberta

  • Kipnes Urology Centre - Kaye Edmonton Clinic - Edmonton
  • University of British Columbia - Vancouver

California

  • University of California Los Angeles, Department of Urology - Los Angeles

Quebec

  • CIUSSS du Nord-de-L'Ile-De-Montreal - Montreal

Other

  • Humanitas - Milan

Trial Details

FieldValue
Enrollment Target 210 participants
Start Date 2022-11-30
Est. Completion 2033-06-30
Phase NA
University of Alberta

19 total trials

What NCT05558241 shows while recruiting

NCT05558241 is an interventional study that assigns participants to a tested intervention. The registered 210 participants enrollment target is mid-sized for trials with a published cap, below the 608-participant average among 735 other Prostate Cancer trials with a reported enrollment target (65% lower).

The record links to 1 condition, with Prostate Cancer appearing as the primary indexed condition, and to 1 intervention - of which High-resolution micro-ultrasound is the first listed.

NCT05558241 lists 5 locations in 4 states (Alberta, California, Quebec).

Frequently Asked Questions

What is clinical trial NCT05558241 about?

NCT05558241 is a clinical study titled "Micro-UltraSound In Cancer - Active Surveillance". This study will compare the two imaging modalities (MRI and micro-ultrasound) during Active Surveillance of prostate cancer (PCa). Progression to clinically significant PCa will be assessed by first taking micro-US targeted samples (while blinded to MRI results), followed by MRI targeted samples, fi...

What is the current status of trial NCT05558241?

This trial is currently recruiting. It is a NA study. The enrollment target is 210 participants. The study started on 2022-11-30. Estimated completion is 2033-06-30.

What conditions does trial NCT05558241 study?

This clinical trial studies the following conditions: Prostate Cancer.

What interventions are being tested in trial NCT05558241?

The interventions under investigation include: High-resolution micro-ultrasound (DEVICE).

Who is sponsoring clinical trial NCT05558241?

This trial is sponsored by University of Alberta, which has 19 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05558241 being conducted?

This trial has 5 study locations across California, Alberta, Quebec. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Prostate Cancer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05558241's enrollment target sits among peer trials

210 216th of 735 higher than 519 of 735 other Prostate Cancer trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Prostate Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02665923 · 210 participants

    Gastric Emptying in Neonates and Infants After Formula Feeding

  • NCT03544489 · 210 participants · Phase 2

    Effectiveness of Exercise After an ICD

  • NCT04408430 · 210 participants · NA

    The MITRAL II Pivotal Trial (Mitral Implantation of TRAnscatheter vaLves).

  • NCT04460573 · 210 participants · Phase 2

    Smart Boot Use to Measure Offloading Adherence

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT05558241, the US trial registry maintained by the National Library of Medicine. NCT05558241 (mid enrollment · multi site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.