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Micro-UltraSound In Cancer - Active Surveillance
NCT05558241 · View on ClinicalTrials.gov ↗
Study Summary
This study will compare the two imaging modalities (MRI and micro-ultrasound) during Active Surveillance of prostate cancer (PCa). Progression to clinically significant PCa will be assessed by first taking micro-US targeted samples (while blinded to MRI results), followed by MRI targeted samples, finishing with 12 systematic biopsy cores. The primary goal is to compare microUS to MRI for the detection of ≥GG2 PCa at confirmatory biopsy. This study will also collect blood samples from participants to be used for future biomarker studies.
Conditions Studied
Interventions
- DEVICE High-resolution micro-ultrasound
Study Locations (5)
Alberta
- Kipnes Urology Centre - Kaye Edmonton Clinic — Edmonton
- University of British Columbia — Vancouver
California
- University of California Los Angeles, Department of Urology — Los Angeles
Quebec
- CIUSSS du Nord-de-L'Ile-De-Montreal — Montreal
Other
- Humanitas — Milan
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 210 participants |
| Start Date | 2022-11-30 |
| Est. Completion | 2033-06-30 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05558241
The ClinicalTrials.gov registry entry for NCT05558241 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 210 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Alberta, which has 135 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Prostate Cancer appearing as the primary indexed condition, and to 1 intervention — of which High-resolution micro-ultrasound is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05558241 reports 5 study locations spanning 4 distinct geographic areas — top geographies include Alberta, California, Quebec. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05558241 about?
NCT05558241 is a clinical study titled "Micro-UltraSound In Cancer - Active Surveillance". This study will compare the two imaging modalities (MRI and micro-ultrasound) during Active Surveillance of prostate cancer (PCa). Progression to clinically significant PCa will be assessed by first taking micro-US targeted samples (while blinded to MRI results), followed by MRI targeted samples, fi...
What is the current status of trial NCT05558241?
This trial is currently recruiting. It is a NA study. The enrollment target is 210 participants. The study started on 2022-11-30. Estimated completion is 2033-06-30.
What conditions does trial NCT05558241 study?
This clinical trial studies the following conditions: Prostate Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05558241?
The interventions under investigation include: High-resolution micro-ultrasound (DEVICE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05558241?
This trial is sponsored by University of Alberta, which has 135 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05558241 being conducted?
This trial has 5 study locations across California, Alberta, Quebec. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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