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PreDiabetes: full-pipeline trial registry
69 of 150 indexed PreDiabetes trials are currently recruiting.
Corpus placement: #78 of 28,707 conditions by registered trial count.
150 US clinical trials · 69 currently recruiting · #78 of 28,707 conditions by registered trial count
PreDiabetes: 150 US clinical trials tracked, 69 recruiting.
PreDiabetes is the subject of 150 registered US clinical trials on ClinicalTrials.gov, 69 of them currently open to new participants. 7 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is Ohio State University, running 5 of these trials.
Enrollment posture brief
Registry condition prediabetes
OPEN 69 | RECR 46% | LATE 7 | EARLY 9 | RANK #78 | SPON 5
Volume-matched condition peers
Nearest open-share peer: Chronic Pain (46% recruiting · 302 trials)
PreDiabetes lists 69 open slots (46% of 150 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for PreDiabetes on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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PreDiabetes is recruiting above its size-band peers.
69 of 150 indexed trials (46%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of PreDiabetes trials is spread across many organizations.
Ohio State University accounts for 5 of 150 trials (3.3%). 97 distinct sponsors appear on at least one study for this condition label.
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Typical PreDiabetes enrolment sits around 80 participants.
Median target enrolment is 80 among the 150 trials that report a genuine target (sentinel values excluded). 87 of those (58%) plan for fewer than 100 participants.
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PreDiabetes research is mostly interventional.
135 interventional and 15 observational studies make up this index (90% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
150 total, page 1 of 3
Diabetes Clinical Decision Support
Milton S. Hershey Medical Center
NCT05447806
Triage Survey for Cardiovascular, Obesity, and Related Endocrine Trial Eligibility
Brooklyn Clinical Research
NCT06412536
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
Cleerly
NCT06112418
Non-interventional Pre-screening Protocol Aims to Evaluate Participants for Potential Trial Eligibility in Future Clinical Trials/Studies Focusing on Metabolic and Psychiatric Health.
Clindove Research
NCT07106879
Glycemic Metrics and Patterns in People With and Without Prediabetes
Abbott Diabetes Care
NCT06921902
Blood Markers of Early Pancreas Cancer
University of Nebraska
NCT03568630
Strategies for Implementing a Postpartum Lifestyle Intervention in WIC Clinics
Tulane University
NCT06116149
Community Engagement Alliance Against Disparities
Johns Hopkins University
NCT06607341
Fresh Takes!: An Evaluation of the Impact of Receiving Fresh Food Boxes
Montefiore Medical Center
NCT06019624
Social Determinants and a Diabetes Prevention Program Tailored for African Americans
University of Missouri, Kansas City
NCT05301413
Inflammation, Diabetes, Ethnicity and Obesity Cohort
University of California, San Francisco
NCT03022682
Black Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention
Ohio State University
NCT06055036
Pharmacogenetics of the Response to GLP-1 in Mexican-Americans With Prediabetes
The University of Texas Health Science Center, Houston
NCT05119179
Mechanisms of Prediabetic States in Sleep Apnea
University of Chicago
NCT04234217
Sisters of Heart (Hermanas de Corazón): A Community Health Worker Initiative for Improving Heart Health in Migrant Farmworker Women
Emory University
NCT07111026
Effects of Walking in Greenspace and the Built Environment in Adults With Prediabetes: A Randomized Crossover Trial
University of Minnesota
NCT06365723
The GRoceries Aimed at Increasing Nutrition Study
University of Pennsylvania
NCT07167004
Food as Medicine for HIV and Diabetes
University of North Carolina, Chapel Hill
NCT05026723
Human Immunodeficiency Virus (HIV) Food Insecurities
Wake Forest University Health Sciences
NCT04943861
Stand Up for Your Health with a Sit-stand Desk
Medical College of Wisconsin
NCT05585190
Understanding Metabolism and Inflammation Risks for Diabetes in Adolescents
University of Michigan
NCT06007404
Cleaner Air for Lower Cardiometabolic Risk
NYU Langone Health
NCT05994937
Rural Alliance for Diabetes Prevention
University of Kansas Medical Center
NCT06252038
Efficacy of Viome's Precision Nutrition Program Towards Reducing HbA1c
Viome
NCT05465616
Dietary Supplementation on Body Fat Composition
Brightseed
NCT06296251
MEAL TIMING Study: Effect of Time-Restricted Feeding on 24-hour Glycemic Control, Blood Pressure, and Cardiovascular Disease Risk Factors in Adults With Prediabetes
University of Alabama at Birmingham
NCT03504683
Long Term Impact of Time-Restricted Eating on Parameters of Cardiometabolic Health
University of California, San Diego
NCT07189234
Primary and Secondary Prevention of Type 2 Diabetes Mellitus in Clark County
University of Nevada, Las Vegas
NCT06387797
Longitudinal Multi-Omic Profiles to Reveal Mechanisms of Obesity-Mediated Insulin Resistance
Stanford University
NCT05165706
Treatment to Regress to Normoglycemia in Women with a Recent History of GDM
Woman's
NCT04873050
Post Prandial Individual Responses to Different Foods
Stanford University
NCT06989164
Puberty, Diabetes, and the Kidneys, When Eustress Becomes Distress (PANTHER Study)
Petter Bjornstad
NCT05008276
The Effects of Mirabegron and Tadalafil on Glucose Tolerance in Prediabetics
Philip Kern
NCT05051436
The YMCA Healthy Lifestyle Program for Prediabetes
Young Men's Christian Association of the Blue Water Area
NCT06841796
Effect of Increased Physical Activity and Stopping Evening Snacking in Metabolic Health in Youth With Prediabetes
Baylor College of Medicine
NCT06782906
New T-UP: Engaging Vulnerable Students in Diabetes Prevention
University of California, Los Angeles
NCT07225218
MegaNatural BP® GSE on Blood Pressure and Cardiometabolic Risk Factors
Clinical Nutrition Research Center, Illinois Institute of Technology
NCT06555952
Mechanisms of Fatigability With Diabetes
University of Michigan
NCT04442451
Effect of Meal Composition and Timing Modification on Glucose Metabolism, Body Temperature and Sleep
Stanford University
NCT05413928
Peanuts for Cardiometabolic, Brain, and Intestinal Health
Georgia State University
NCT06867198
Night Owl Metabolism
Johns Hopkins University
NCT06507722
CGM Dynamic Index for Predicting Prediabetes in Cystic Fibrosis
Indiana University
NCT06642610
Breaking up Sedentary Time to Improve Glucose Control in a Population at Risk for Developing Type 2 Diabetes
University of Colorado, Denver
NCT05041491
Mechanisms for Activation of Beige Adipose Tissue in Humans
Philip Kern
NCT04666636
Prevention of Progression of Prediabetes, Obesity and CV Risk
The University of Texas Health Science Center at San Antonio
NCT06446531
The Role of Islet GLP-1 in the Pathogenesis of Prediabetes
Mayo Clinic
NCT06967558
Insulin and Insulin Pulses During Fasting
Mayo Clinic
NCT06424015
Effect of Glucagon on Fasting Insulin Secretion and Glucose Metabolism in Subjects Without Type 2 Diabetes
Mayo Clinic
NCT06424106
How a Mediterranean Diet With Potatoes Impacts Heart and Metabolic Health in Adults With Pre-Diabetes
University of Nevada, Las Vegas
NCT06817252
Effects of Dihydroberberine (DHB) on GLP-1, Glycemic Control, Appetite, and Mood in Adults With Pre-Diabetes
Nanjing Nutrabuilding Bio-tech Co.
NCT07210684
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 4 |
| Phase 2 | 5 |
| Phase 3 | 1 |
| Phase 4 | 6 |
Top Sponsors
Named interventions
Most-linked intervention names on PreDiabetes records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on PreDiabetes trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this PreDiabetes page
150 registered trials, 69 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 69 PreDiabetes trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Ohio State University sponsors the most PreDiabetes trials on record, review their full trial history before evaluating a specific study. See Ohio State University's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This PreDiabetes condition card totals 150 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.