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NCT07210684 · ClinicalTrials.gov registry record · NA

Effects of Dihydroberberine (DHB) on GLP-1, Glycemic Control, Appetite, and Mood in Adults With Pre-Diabetes

A NA study of PreDiabetes, sponsored by Nanjing Nutrabuilding Bio-tech Co..

Recruiting
Registry status
NA
Development phase
54
Enrollment target
1
Study location

NCT07210684 is a NA study of PreDiabetes that is actively recruiting participants, run by Nanjing Nutrabuilding Bio-tech Co.. The registered enrollment target is 54 participants, below the 690-participant average among 89 other PreDiabetes trials with a reported enrollment target (92% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT07210684, a NA study of PreDiabetes, is actively recruiting participants, sponsored by Nanjing Nutrabuilding Bio-tech Co..

RECRUITING
Registry status
NA
Development phase
54 participants
Enrollment target
1
Study location

Study Summary

The goal of this clinical trial is to learn if Dihydroberberine (DHB) supplementation affects adults with pre-diabetes. The main questions it aims to answer are: Does DHB supplementation increase the concentration of GLP-1 in the blood? Does DHB supplementation affect appetite, mood, and energy levels? Does DHB supplementation affect body weight, blood sugar control and insulin? Researchers will compare DHB supplementation to a placebo (a look-alike substance that contains no drug) to see if DHB has any effect. Participants will: Take DHB or a placebo every day for 6 weeks. Participate in tests to measure GLP-1 levels, blood glucose, insulin and other markers. Have their continuous blood sugar profiles (with CGMs) monitored to see how much time their blood sugar spends in a healthy range. Rate their appetite, mood, and energy levels using a visual analog scale.

Conditions Studied

PreDiabetes

Interventions

  • DIETARY_SUPPLEMENT Placebo 400 mg
  • DIETARY_SUPPLEMENT Dihydroberberine（DHB）400 mg

Study Locations (1)

Illinois

  • Merieux NutriSciences - Addison

Trial Details

FieldValue
Enrollment Target 54 participants
Start Date 2025-08-06
Est. Completion 2026-03-15
Phase NA

Sponsor

Nanjing Nutrabuilding Bio-tech Co.

2 total trials

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What the Registry Record Tells You About NCT07210684

The ClinicalTrials.gov registry entry for NCT07210684 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 54 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 690-participant average among 89 other PreDiabetes trials with a reported enrollment target (92% lower). The listed sponsor is Nanjing Nutrabuilding Bio-tech Co., which has 2 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with PreDiabetes appearing as the primary indexed condition, and to 2 interventions - of which Placebo 400 mg is the first listed.

NCT07210684 reports 1 study location spanning 1 distinct geographic area - top geographies include Illinois.

Frequently Asked Questions

What is clinical trial NCT07210684 about?

NCT07210684 is a clinical study titled "Effects of Dihydroberberine (DHB) on GLP-1, Glycemic Control, Appetite, and Mood in Adults With Pre-Diabetes". The goal of this clinical trial is to learn if Dihydroberberine (DHB) supplementation affects adults with pre-diabetes. The main questions it aims to answer are: Does DHB supplementation increase the concentration of GLP-1 in the blood? Does DHB supplementation affect appetite, mood, and energy le...

What is the current status of trial NCT07210684?

This trial is currently recruiting. It is a NA study. The enrollment target is 54 participants. The study started on 2025-08-06. Estimated completion is 2026-03-15.

What conditions does trial NCT07210684 study?

This clinical trial studies the following conditions: PreDiabetes.

What interventions are being tested in trial NCT07210684?

The interventions under investigation include: Placebo 400 mg (DIETARY_SUPPLEMENT), Dihydroberberine（DHB）400 mg (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT07210684?

This trial is sponsored by Nanjing Nutrabuilding Bio-tech Co., which has 2 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07210684 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.