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NCT05585190 · ClinicalTrials.gov registry record · NA
Stand Up for Your Health with a Sit-stand Desk
A NA study of Obesity and Metabolic Syndrome, sponsored by Medical College of Wisconsin.
- Recruiting
- Registry status
- NA
- Development phase
- 198
- Enrollment target
- 1
- Study location
NCT05585190 is a NA study of Obesity and Metabolic Syndrome that is actively recruiting participants, run by Medical College of Wisconsin. The registered enrollment target is 198 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (76% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05585190, a NA study of Obesity and Metabolic Syndrome, is actively recruiting participants, sponsored by Medical College of Wisconsin.
- RECRUITING
- Registry status
- NA
- Development phase
- 198 participants
- Enrollment target
- 1
- Study location
Study Summary
More than 84 million - or 1 out of every 3 U.S. adults - have prediabetes, a condition that if not treated often leads to type 2 diabetes within five years. Average medical expenditures among diabetics are about 2.3 times higher than expenditures for people without diabetes. Physical inactivity and elevated body mass index (BMI) are major risk factors for the disease. Sedentary behavior is becoming increasingly prevalent with the growth of a 'work from home' culture, most recently driven by the COVID-19 pandemic. Cross-sectional epidemiologic data report significant associations between high amounts of sedentary (sitting) time and prevalent cardiovascular disease and diabetes. In our pilot study of 15 subjects with sedentary office jobs, 6 months of sit-stand desk use resulted in a 23% improvement in insulin resistance, most substantial in those who decreased daily sitting by over 90 minutes/day. Additional improvements in vascular endothelial function and triglyceride levels were seen without any change in exercise activity, step counts, or body weight. These findings not only corroborate epidemiologic findings on this topic but suggest causality and warrant a randomized control trial. The investigators hypothesize that adult subjects at-risk for diabetes will improve insulin sensitivity, metabolic and vascular (endothelial) health with a sit-stand desk intervention at work (whether in the office or at home), in the context of a randomized, controlled trial. The investigators will randomize 198 sedentary office workers with a BMI≥25 at risk for type 2 diabetes mellitus in a 1:1:1 ratio of three groups: (a) sit-stand desk intervention targeting 2 hours standing per day; (b) sit-stand desk intervention targeting 3 hours standing per day; or (c) control arm over 6 months. The block randomization design will allow for important dose-response analyses. The investigators will objectively quantify standing time, sedentary time, sedentary bouts, daily steps, and exercise
Conditions Studied
Interventions
- OTHER Control
- OTHER Sit-Stand Desk at Work
Study Locations (1)
Wisconsin
- Medical College of Wisconsin - Milwaukee
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 198 participants |
| Start Date | 2023-02-06 |
| Est. Completion | 2027-12-31 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05585190
The ClinicalTrials.gov registry entry for NCT05585190 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 198 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (76% lower). The listed sponsor is Medical College of Wisconsin, which has 447 total studies on file at ClinicalTrials.gov.
The record links to 4 conditions, with Obesity appearing as the primary indexed condition, and to 2 interventions - of which Control is the first listed.
NCT05585190 reports 1 study location spanning 1 distinct geographic area - top geographies include Wisconsin.
Frequently Asked Questions
What is clinical trial NCT05585190 about?
NCT05585190 is a clinical study titled "Stand Up for Your Health with a Sit-stand Desk". More than 84 million - or 1 out of every 3 U.S. adults - have prediabetes, a condition that if not treated often leads to type 2 diabetes within five years. Average medical expenditures among diabetics are about 2.3 times higher than expenditures for people without diabetes. Physical inactivity and ...
What is the current status of trial NCT05585190?
This trial is currently recruiting. It is a NA study. The enrollment target is 198 participants. The study started on 2023-02-06. Estimated completion is 2027-12-31.
What conditions does trial NCT05585190 study?
This clinical trial studies the following conditions: Obesity, Metabolic Syndrome, Pre Diabetes, Sedentary Behavior.
What interventions are being tested in trial NCT05585190?
The interventions under investigation include: Control (OTHER), Sit-Stand Desk at Work (OTHER).
Who is sponsoring clinical trial NCT05585190?
This trial is sponsored by Medical College of Wisconsin, which has 447 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05585190 being conducted?
This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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