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PreDiabetes: full-pipeline trial registry
69 of 150 indexed PreDiabetes trials are currently recruiting.
Corpus placement: #78 of 28,707 conditions by registered trial count.
150 US clinical trials · 69 currently recruiting · #78 of 28,707 conditions by registered trial count
PreDiabetes: 150 US clinical trials tracked, 69 recruiting.
PreDiabetes is the subject of 150 registered US clinical trials on ClinicalTrials.gov, 69 of them currently open to new participants. 7 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is Ohio State University, running 5 of these trials.
Enrollment posture brief
Registry condition prediabetes
OPEN 69 | RECR 46% | LATE 7 | EARLY 9 | RANK #78 | SPON 5
Volume-matched condition peers
Nearest open-share peer: Chronic Pain (46% recruiting · 302 trials)
PreDiabetes lists 69 open slots (46% of 150 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for PreDiabetes on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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PreDiabetes is recruiting above its size-band peers.
69 of 150 indexed trials (46%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of PreDiabetes trials is spread across many organizations.
Ohio State University accounts for 5 of 150 trials (3.3%). 97 distinct sponsors appear on at least one study for this condition label.
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Typical PreDiabetes enrolment sits around 80 participants.
Median target enrolment is 80 among the 150 trials that report a genuine target (sentinel values excluded). 87 of those (58%) plan for fewer than 100 participants.
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PreDiabetes research is mostly interventional.
135 interventional and 15 observational studies make up this index (90% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
150 total, page 2 of 3
Continuous Glucose Monitoring (CGM) in Prediabetes With Health Education Videos: Cohort 3
David S Black, PhD
NCT07477249
The Role of Type 2 Diabetes on Skeletal Muscle Atrophy and Recovery Following Bed Rest in Older Adults
AdventHealth Translational Research Institute
NCT03761446
Full Plate Living Nutrition Education Program
University of Wisconsin, Madison
NCT07271940
Ketogenic Diet and Diabetes Demonstration Project
University of New Mexi
NCT06115265
Nested Pilot Study Comparing Two Treatments to Reduce Type 2 Diabetes Risk in At-Risk Delawareans
University of Delaware
NCT07450118
Mobile Health Dietary Intervention for Stroke Survivors With Prediabetes or Type 2 Diabetes
University of Hawaii
NCT07120334
Lifestyle Patterns and Glycemic Control
Columbia University
NCT05224986
Dinner Time for Obesity and Prediabetes
Johns Hopkins University
NCT05745441
Glucose Variability and Cognition in Prediabetes
University of Maryland, Baltimore
NCT04201600
Whole Food for Families: A Pilot RCT of a Dietary Guidelines-Based Intervention to Prevent Type 2 Diabetes
Vanderbilt University
NCT06482944
Behavioral Approach for Latinas Addressing Nutrition, Cravings, and Eating Patterns to Prevent Type 2 Diabetes
University of California, San Diego
NCT07478263
WatchWell: Simple and Practical Strategies to Reduce the Negative Health Impact of Sedentary Screen Time
Arizona State University
NCT06963736
Development of an Inclusive Adaptive Treatment Strategy for Weight Loss in People With Prediabetes Using a Sequential Multiple Assignment Randomized Trial
University of Alabama at Birmingham
NCT06976307
Optimizing Mango's Glycemic Impact: Investigating Mango Consumption Timing in Prediabetic Individuals
Clinical Nutrition Research Center, Illinois Institute of Technology
NCT06986161
Medically Intensive Nutrition Therapy Program for Obesity and Diabetes in a Low-income Population
Massachusetts General Hospital
NCT05799222
Feasibility of a Nutrition Intervention for Patients With Prediabetes at a Federally Qualified Health Center
Cedars-Sinai Medical Center
NCT06897982
Pilot Study of "Bottarga" Supplementation: A Little-known, Sustainable "Blue" Food
Cambridge Health Alliance
NCT06988462
Effects of Lean Pork Loin Intake on Protein Homeostasis and Glucose Regulation in Prediabetic Adults
University of Arkansas
NCT06025292
CGM and Lifestyle Changes in Patients With Impaired Glucose Tolerance
Nemours Children's Clinic
NCT05387551
Use of Continuous Glucose Monitoring in Non-Diabetic Population to Compliment Signos Mobile Health Platform
Signos
NCT05121844
The PIVOT Trial: Project on EHR-Integrated Lifestyle Interventions for Adults Aged Fifty and Older
University of Illinois at Chicago
NCT05654142
Northern Manhattan Study of Metabolism and Mind
Columbia University
NCT02470260
Behavioral Nudges for Diabetes Prevention (BEGIN) Trial in Primary Care
Northwestern University
NCT04869917
Evaluation of a Telehealth DPP With Medicare Patients at the University of Mississippi Medical Center
University of Mississippi Medical Center
NCT04822480
Randomized Trial of Exercise Promotion in Primary Care
Kaiser Permanente
NCT04445168
Promoting Successful Weight Loss in Primary Care in Louisiana Using Information Technology
Pennington Biomedical Research Center
NCT05523375
A Shared Decision Making Intervention for Diabetes Prevention in Women With a History of Gestational Diabetes Mellitus
University of California, Los Angeles
NCT04897945
Pharmacists' Delivery of Education to Prevent Diabetes in the New Orleans Hospitality Industry
Xavier University of Louisiana.
NCT07451314
Stepping Into Lifestyle Changes
University of Alabama at Birmingham
NCT05625321
BRInging the Diabetes Prevention Program to GEriatric Populations
NYU Langone Health
NCT05166785
Technology-Supported Treatment of Sleep Apnea in Prediabetes
University of Chicago
NCT04225507
The Inspiring Action to Prevent Diabetes Intervention
University of Michigan
NCT06001801
Mastering Diabetes Study
Ohio University
NCT04454957
Precision Diets for Diabetes Prevention
Stanford University
NCT03919877
An Open-Label Pilot Intervention Trial to Prevent Diabetes in Prediabetic Adult Survivors of Childhood Cancer
St. Jude Children's Research Hospital
NCT04742751
The Renin-Angiotensin-Aldosterone System in Adiposity, Blood Pressure and Glucose in African Americans
Ohio State University
NCT03938389
Examining the Effects of Vivo on Physical Function and Glycemic Level in Sedentary Older With Prediabetes.
Impactiv
NCT06458530
Understanding Dose Related Effects of Strawberry
Clinical Nutrition Research Center, Illinois Institute of Technology
NCT06173765
Assessing Gut Microbiota Mediated Health Outcomes of Whole Wheat and Its Major Bioactive Components
Ohio State University
NCT05318183
Use of Empagliflozin to Treat Prediabetes
Oregon State University
NCT05426525
Recreational Basketball to Increase Participation in Diabetes Prevention
Kaiser Permanente
NCT05066542
TREAT to Improve Cardiometabolic Health
Columbia University
NCT04465721
Monounsaturated Fatty Acid Supplementation for Overweight and Obese Individuals With Prediabetes
Brigham and Women's Hospital
NCT05560971
Cephalic Phase Responses to Nutritive and Non-Nutritive Sweeteners
Purdue University
NCT06387316
The Effect of Exercise and Nicotinamide Riboside Muscle Health and Insulin Resistance in Survivors of Childhood Cancer
City of Hope Medical Center
NCT05023993
Is the Degree of Perceived Effort During Resistance Exercise Important for Improvements in Blood Glucose
University of New Mexi
NCT06208189
Comparison of Outreach Methods to Encourage Enrollment in Diabetes Prevention and Weight Management Programs
Kaiser Permanente
NCT03200535
Vitamin D and Type 2 Diabetes Study
Tufts Medical Center
NCT01942694
Integrated Community-Clinical Linkage Model to Promote Weight Loss Among South Asians With Pre-Diabetes
NYU Langone Health
NCT03188094
Conventional and Metabolomic Predictors of Prediabetes & Insulin Resistance
University of Michigan
NCT05055219
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 4 |
| Phase 2 | 5 |
| Phase 3 | 1 |
| Phase 4 | 6 |
Top Sponsors
Named interventions
Most-linked intervention names on PreDiabetes records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on PreDiabetes trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this PreDiabetes page
150 registered trials, 69 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 69 PreDiabetes trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Ohio State University sponsors the most PreDiabetes trials on record, review their full trial history before evaluating a specific study. See Ohio State University's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This PreDiabetes condition card totals 150 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.