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NCT06507722 · ClinicalTrials.gov registry record · NA
Night Owl Metabolism
A NA study of Overweight and PreDiabetes, sponsored by Johns Hopkins University.
- Recruiting
- Registry status
- NA
- Development phase
- 70
- Enrollment target
- 1
- Study location
NCT06507722 is a NA study of Overweight and PreDiabetes that is actively recruiting participants, run by Johns Hopkins University. The registered enrollment target is 70 participants, below the 1,323-participant average among 197 other Overweight trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06507722, a NA study of Overweight and PreDiabetes, is actively recruiting participants, sponsored by Johns Hopkins University.
- RECRUITING
- Registry status
- NA
- Development phase
- 70 participants
- Enrollment target
- 1
- Study location
Study Summary
The proposed study uses a novel and rigorous randomized cross-over study design in youth (17-23y) with late and non-late chronotype (n=35 per group) to assess the glycemic effect of "aligning" an oral glucose tolerance test (OGTT) or first-meal of day to a subject's chronotype. Both groups will undergo 2 OGTTs (aligned and mis-aligned with chronotype) to compare glucose tolerance and insulin sensitivity within-subject (primary outcome) and between groups (Aim 1). Then, youth will also undergo two standardized meals (aligned and mis-aligned with chronotype) while wearing continuous glucose monitoring to compare post-prandial glucose excursions within-subject and between groups (Aim 2). A pilot Exploratory Aim 3 (n=12 per group) will investigate delayed melatonin patterns under dim-light as a potential pathophysiologic mechanism behind abnormal glucose tolerance in youth with late chronotype on morning OGTTs.
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Timing of OGTT
- BEHAVIORAL Timing of Standardized Meal
Study Locations (1)
Maryland
- Johns Hopkins School of Medicine - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2025-02-25 |
| Est. Completion | 2030-01-31 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06507722
The ClinicalTrials.gov registry entry for NCT06507722 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 70 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,323-participant average among 197 other Overweight trials with a reported enrollment target (95% lower). The listed sponsor is Johns Hopkins University, which has 1,448 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Overweight appearing as the primary indexed condition, and to 2 interventions - of which Timing of OGTT is the first listed.
NCT06507722 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.
Frequently Asked Questions
What is clinical trial NCT06507722 about?
NCT06507722 is a clinical study titled "Night Owl Metabolism". The proposed study uses a novel and rigorous randomized cross-over study design in youth (17-23y) with late and non-late chronotype (n=35 per group) to assess the glycemic effect of "aligning" an oral glucose tolerance test (OGTT) or first-meal of day to a subject's chronotype. Both groups will unde...
What is the current status of trial NCT06507722?
This trial is currently recruiting. It is a NA study. The enrollment target is 70 participants. The study started on 2025-02-25. Estimated completion is 2030-01-31.
What conditions does trial NCT06507722 study?
This clinical trial studies the following conditions: Overweight, PreDiabetes, Impaired Glucose Tolerance.
What interventions are being tested in trial NCT06507722?
The interventions under investigation include: Timing of OGTT (DIAGNOSTIC_TEST), Timing of Standardized Meal (BEHAVIORAL).
Who is sponsoring clinical trial NCT06507722?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06507722 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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