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NCT05165706 · ClinicalTrials.gov registry record · NA
Longitudinal Multi-Omic Profiles to Reveal Mechanisms of Obesity-Mediated Insulin Resistance
A NA study of Obesity and Diabetes Mellitus, Type 2, sponsored by Stanford University.
- Recruiting
- Registry status
- NA
- Development phase
- 110
- Enrollment target
- 1
- Study location
NCT05165706: Recruiting NA study of Obesity and Diabetes Mellitus, Type 2, sponsored by Stanford University.
NCT05165706 is a NA study of Obesity and Diabetes Mellitus, Type 2 that is actively recruiting participants, run by Stanford University. The registered enrollment target is 110 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05165706, a NA study of Obesity and Diabetes Mellitus, Type 2, is actively recruiting participants, sponsored by Stanford University.
- RECRUITING
- Registry status
- NA
- Development phase
- 110 participants
- Enrollment target
- 1
- Study location
Study Summary
This 12-week controlled diet and weight intervention study seeks to define the molecular pathways that link excess body weight to the development of insulin resistance (IR). Blood, adipose and stool are sampled at three timepoints; baseline, peak weight (4 weeks) and post weight loss to monitor changes in cellular processes. Additionally, direct insulin sensitivity testing, and radiological measurement of visceral fat and intrahepatic fat content is measured at three timepoints to correlate clinical indices with cellular changes.
Primary Outcome
Compare direct measurement of insulin sensitivity after 4 week diet and weight intervention
Conditions Studied
Interventions
- BEHAVIORAL Dietary Intervention Mediterranean Low Carbohydrate Diet
- BEHAVIORAL Dietary Intervention Standard Low Carbohydrate Diet
- BEHAVIORAL Dietary Intervention Standard Low Fat Diet
Study Locations (1)
California
- Stanford University - Stanford
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 110 participants |
| Start Date | 2019-01-31 |
| Est. Completion | 2026-12-30 |
| Phase | NA |
What NCT05165706 shows while recruiting
NCT05165706 is an interventional study that assigns participants to a tested intervention. The registered 110 participants enrollment target is mid-sized for trials with a published cap, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (87% lower).
The record links to 7 conditions, with Obesity appearing as the primary indexed condition, and to 3 interventions - of which Dietary Intervention Mediterranean Low Carbohydrate Diet is the first listed.
NCT05165706 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT05165706 about?
NCT05165706 is a clinical study titled "Longitudinal Multi-Omic Profiles to Reveal Mechanisms of Obesity-Mediated Insulin Resistance". This 12-week controlled diet and weight intervention study seeks to define the molecular pathways that link excess body weight to the development of insulin resistance (IR). Blood, adipose and stool are sampled at three timepoints; baseline, peak weight (4 weeks) and post weight loss to monitor chan...
What is the current status of trial NCT05165706?
This trial is currently recruiting. It is a NA study. The enrollment target is 110 participants. The study started on 2019-01-31. Estimated completion is 2026-12-30.
What conditions does trial NCT05165706 study?
This clinical trial studies the following conditions: Obesity, Diabetes Mellitus, Type 2, PreDiabetes, Insulin Resistance, Nonalcoholic Steatohepatitis.
What interventions are being tested in trial NCT05165706?
The interventions under investigation include: Dietary Intervention Mediterranean Low Carbohydrate Diet (BEHAVIORAL), Dietary Intervention Standard Low Carbohydrate Diet (BEHAVIORAL), Dietary Intervention Standard Low Fat Diet (BEHAVIORAL).
Who is sponsoring clinical trial NCT05165706?
This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05165706 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obesity
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05165706's enrollment target sits among peer trials
110 458th of 1053 higher than 594 of 1,053 other Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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