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Atopic Dermatitis
Open-data reference.
151 US clinical trials · 55 currently recruiting
Active & Recent Trials
Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives
Sanguine Biosciences
NCT05635266
An Observational Retrospective Cohort Study Being Conducted in Women With Atopic Dermatitis Exposed to Ruxolitinib Cream Versus Topical Corticosteroids During Pregnancy: A US Claims Database Analysis
Incyte Corporation
NCT06627335
An Observational Retrospective Cohort Study Being Conducted in Women With Atopic Dermatitis (AD)
Regeneron Pharmaceuticals
NCT03936335
Natural History and Genetics of Food Allergy and Related Conditions
National Institute of Allergy and Infectious Diseases (NIAID)
NCT02504853
CorEvitas International Adolescent Atopic Dermatitis (AD) Drug Safety and Effectiveness Registry
CorEvitas
NCT06238765
This Study is a Non-interventional Disease Registry of Adolescent and Adult Patients With Atopic Dermatitis Who Initiate or Switch Any Systemic Treatment
Sanofi
NCT07290803
Real-world Experience Using Nemolizumab in the Treatment of Moderate-to-Severe Atopic Dermatitis in Adolescents & Adults
Galderma R&D
NCT06988605
Study to Compare Maternal, Fetal, and Infant Outcomes of Women With Mild to Moderate Atopic Dermatitis Exposed to Ruxolitinib Cream During Pregnancy With an Unexposed Control Population
Incyte Corporation
NCT06259669
Monitoring Pregnancy and Infant Outcomes Following Tralokinumab Exposure During Pregnancy in the US and Canada - PROTECT
University of California, San Diego
NCT05938478
A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis
AbbVie
NCT06461897
Studies of Skin Microbes in Healthy People and in People With Skin Conditions
National Human Genome Research Institute (NHGRI)
NCT00605878
A Long-term Study of the Medicine Called Abrocitinib in Children Aged 2 Years and Older With Moderate to Severe Eczema
Pfizer
NCT06807281
Registry for Systemic Eczema Treatments
Johns Hopkins University
NCT06136767
A Study of How Safe Abrocitinib (CIBINQO) is in Pregnant Women and Their Offspring
Pfizer
NCT05721937
A Long-term Safety and Efficacy Study Evaluating APG777 in Atopic Dermatitis
Apogee Therapeutics
NCT07003425
A Study To Learn About Two Study Medicines (PF-07275315 And PF-07264660) In People Who Have Moderate To Severe Atopic Dermatitis
Pfizer
NCT05995964
Metabolic Profiling of Immune Responses in Immune-mediated Diseases
National Institute of Allergy and Infectious Diseases (NIAID)
NCT04864886
Skin Microbial Ecology in Atopic Dermatitis
University of Rochester
NCT04170244
A Study to Assess the Efficacy and Safety of Ruxolitinib Cream in Children and Adolescents (6 to <18 Years Old) With Moderate Atopic Dermatitis
Incyte Corporation
NCT06832618
Platform Study to Evaluate the Efficacy and Safety of Investigational Compound(s) in Patients With Moderate to Severe Atopic Dermatitis
Novartis Pharmaceuticals
NCT06947993
A Study to Evaluate the Efficacy and Safety of IMG-007 in Adult Participants With Moderate-to-Severe Atopic Dermatitis
Inmagene
NCT07037901
A Study to See How Well Lebrikizumab Works in Adults and Adolescents With Moderate Atopic Dermatitis (Eczema) and High Itch Burden
Eli Lilly and Company
NCT07006792
Michigan Food and Atopic Dermatitis (M-FAD) Program - Molecular Analytics Project
University of Michigan
NCT06300697
Blood, Urine, and Tissue Collection for Cutaneous Lymphoma, Eczema, and Atopic Dermatitis Research
University of Pittsburgh
NCT00177268
Study to Evaluate Soquelitinib in Participants With Moderate to Severe AD
Corvus Pharmaceuticals
NCT07441395
A Study of KT-621 Administered Orally to Participants With Moderate to Severe Atopic Dermatitis
Kymera Therapeutics
NCT07217015
A Study of Upadacitinib in Adult Participants With Moderate-to-Severe Atopic Dermatitis and Inadequate Response to Dupilumab
AbbVie
NCT06389136
A Study of BBT001 in Healthy Volunteers (HVs) and in Adult Patients With Atopic Dermatitis (AD)
Bambusa Therapeutics
NCT06808477
A Trial to Evaluate the Efficacy and Safety of Tralokinumab in Combination With Topical Corticosteroids in Children and Infants With Moderate-to-severe Atopic Dermatitis
LEO Pharma
NCT06311682
A Study to Investigate Safety and Efficacy of Tapinarof Cream, 1% in Participants Ages 3 Months to < 24 Months With Atopic Dermatitis
Organon and
NCT07265479
A Study to Assess the Efficacy and Safety of Afimkibart (RO7790121) in Participants With Moderate to Severe Atopic Dermatitis
Hoffmann-La Roche
NCT06863961
A Dose-ranging Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Galvokimig in Adult Study Participants With Atopic Dermatitis
UCB Biopharma SRL
NCT07277660
Real World Efficiency of Abrocitinib Treatment at Patients With Moderate to Severe Atopic Dermatitis Who Had Inadequate Response to Previous Biologic Therapies.
Pfizer
NCT06899204
Cardamom and Topical Roseomonas in Atopic Dermatitis
National Institute of Allergy and Infectious Diseases (NIAID)
NCT06096857
A Long Term Extension Study to Evaluate the Safety and Efficacy of Afimkibart (RO7790121) in Participants With Atopic Dermatitis
Hoffmann-La Roche
NCT07223697
FIH Study to Evaluate the Tolerability of PF-07832837 in Healthy Adults and Patients
Pfizer
NCT06564389
Mechanisms of Increased Disease Severity in AD Patients With the IL-4Ra R576 Polymorphism
Boston Children's Hospital
NCT04455906
A Study to Assess the Efficacy of GX-03 in Moderate to Severe Eczema (Atopic Dermatitis)
Turn Therapeutics
NCT07355075
ATI-045 Versus Placebo in Patients With Moderate-to-Severe Atopic Dermatitis
Aclaris Therapeutics
NCT07011706
Evaluate Efficacy and Safety of Repeat Subcutaneous Doses of FB825 in Adults With Moderate-to-Severe Atopic Dermatitis
Oneness Biotech Co.
NCT06397911
A Study Evaluating TRIV-509 in Atopic Dermatitis
Triveni Bio
NCT07167758
Sodium in the Skin and Atopic Dermatitis
University of California, San Francis
NCT06998446
Targeted Investigation of Microbiome 2 Treat Atopic Dermatitis (TIME-2)
National Institute of Allergy and Infectious Diseases (NIAID)
NCT06504160
Phase 2a Study to Assess the Efficacy,Safety and Tolerability of GIA632 in Adult Participants With Moderate to Severe Atopic Dermatitis
Novartis Pharmaceuticals
NCT07220577
A Study to Assess Molecular Changes in Adult Participants With Moderate to Severe Hidradenitis Suppurativa or With Moderate to Severe Atopic Dermatitis Receiving Subcutaneous Injections of Lutikizumab
AbbVie
NCT06524635
Treatment of Atopic Dermatitis and Alopecia Areata With Abrocitinib in Individuals With Down Syndrome
Icahn School of Medicine at Mount Sinai
NCT07242638
Lebrikizumab in Moderate-to-severe Atopic Dermatitis
Johann E Gudjonsson MD PhD
NCT06906497
A Study to Investigate the Safety, Tolerability, and Efficacy of BxC-I17e Single and Multiple Dose SC Injection in Patients With Moderate to Severe Atopic Dermatitis
Brexogen
NCT06055361
Using Dupilumab to Improve Circadian Function, Sleep and Pruritus in Children With Moderate/Severe Atopic Dermatitis
Northwestern University
NCT05042258
Dupixent and Narrowband UVB for Atopic Dermatitis
Psoriasis Treatment Center of Central New Jersey
NCT05285839
Ethnic Differences in Mechanisms of Action of Dupilumab
University of Michigan
NCT05268107
Topical Treatment for Atopic Dermatitis
Wake Forest University Health Sciences
NCT06244212
Dupilumab De-escalation in Pediatric Atopic Dermatitis
Johns Hopkins University
NCT06116526
Evaluating the Safety and Tolerability of Baricitinib in Patients With Job Syndrome With Lupus-Like Disease and/or Atopic Dermatitis
National Institute of Allergy and Infectious Diseases (NIAID)
NCT07262983
Molecular Signatures of Cutaneous Dupilumab Response
University of California, San Francis
NCT05858619
A Longitudinal Observational Study of Patients Undergoing Therapy for IMISC
Target PharmaSolutions
NCT03661866
10 Year Registry of Children (Ages 2-17 Years) With Eczema That Have Used Pimecrolimus
Bausch Health Americas
NCT00568997
A Study to Assess Long-term Safety, Tolerability, and Efficacy of Rocatinlimab in Adult and Adolescent Participants With Moderate-to-severe Atopic Dermatitis (AD)
Amgen
NCT05882877
Systems Biology of Early Atopy
National Institute of Allergy and Infectious Diseases (NIAID)
NCT04798079
A Study to Evaluate Upadacitinib in Combination With Topical Corticosteroids in Adolescent and Adult Participants With Moderate to Severe Atopic Dermatitis
AbbVie
NCT03568318
Study to Assess the Long-term Safety of Dupilumab Administered in Participants ≥6 Months to <18 Years of Age With Atopic Dermatitis (AD)
Regeneron Pharmaceuticals
NCT02612454
Defining the Skin and Blood Biomarkers of Pediatric Atopic Dermatitis
Northwestern University
NCT01782703
A Study Evaluating APG777 in Atopic Dermatitis
Apogee Therapeutics
NCT06395948
Seal, Stopping Eczema and Allergy Study
Kari Nadeau, MD, PhD
NCT03742414
A Study of Lebrikizumab (LY3650150) in Participants 6 Months to <18 Years of Age With Moderate-to-Severe Atopic Dermatitis
Eli Lilly and Company
NCT05559359
Phase 2 Trial of HY209gel in Atopic Dermatitis Patients
Shaperon
NCT06024499
A Study to Learn About Study Medicine Called PF-08049820 in People With Eczema
Pfizer
NCT07216027
A Study With Self-administered Rocatinlimab in Adolescent and Adult Participants With Moderate-to-severe Atopic Dermatitis
Amgen
NCT06224192
A Study of Barzolvolimab in Patients With Atopic Dermatitis
Celldex Therapeutics
NCT06727552
Evaluating Safety and Efficacy of ADX-914 in Patients With Moderate to Severe Atopic Dermatitis (SIGNAL-AD)
Q32 Bio
NCT05509023
A Study to Evaluate the Effectiveness and Safety of Treatments, Either Alone or in Combination, for the Treatment of Moderate to Severe Atopic Dermatitis
AbbVie
NCT06718101
Tralokinumab for Dupilumab Failures
Psoriasis Treatment Center of Central New Jersey
NCT06773455
A Study to Learn If the Study Medicine Called PF-08049820 Changes How the Body Processes the Other Study Medicines Called Oral Contraceptives, Midazolam, and Dabigatran in Healthy Adult Female Participants
Pfizer
NCT07190430
Bodewell Products for the Treatment of Atopic Dermatitis
University of Alabama at Birmingham
NCT05566262
Asthma and Atopic Dermatitis Validation of PROMIS Pediatric Instruments
Northwestern University
NCT03051347
Evaluation of Upadacitinib in Adolescent and Adult Patients With Moderate to Severe Atopic Dermatitis (Eczema)
AbbVie
NCT03569293
A Study Assessing Rocatinlimab in Combination With Topical Corticosteroid and/or Topical Calcineurin Inhibitors in Adult Participants With Moderate-to-severe Atopic Dermatitis (AD)
Amgen
NCT05724199
Study to Assess the Efficacy and Long-term Safety of Dupilumab (REGN668/SAR231893) in Adult Participants With Moderate-to-Severe Atopic Dermatitis
Regeneron Pharmaceuticals
NCT02260986
A Study Assessing Rocatinlimab (AMG 451) Monotherapy in Moderate-to-severe Atopic Dermatitis (AD) (ROCKET-Horizon)
Amgen
NCT05651711
B244 Topical Spray for the Treatment of Pruritus in Adults With a History of Atopic Dermatitis
AOBiome
NCT04490109
A Study to Evaluate Rocatinlimab (AMG 451) in Adolescent Participants With Moderate-to-severe Atopic Dermatitis (AD)
Amgen
NCT05704738
Evaluation of the Efficacy and Safety of Lebrikizumab (LY3650150) in Moderate to Severe Atopic Dermatitis
Eli Lilly and Company
NCT04178967
Evaluation of the Efficacy and Safety of Lebrikizumab (LY3650150) in Moderate to Severe Atopic Dermatitis (ADvocate1)
Eli Lilly and Company
NCT04146363
Impact of the Severity of Pediatric Psoriasis on Childhood Body Mass Index
Northwestern University
NCT00879944
Tapinarof for the Treatment of Atopic Dermatitis in Children and Adults
Organon and
NCT05014568
Tapinarof for the Treatment of Atopic Dermatitis in Children and Adults (DMVT-505-3102)
Organon and
NCT05032859
Study of Dupilumab Administered to Adult Patients With Moderate-to-Severe Atopic Dermatitis
Regeneron Pharmaceuticals
NCT01859988
Efficacy and Safety Study of Orally Administered DS107 in Moderate to Severe Atopic Dermatitis Patients
DS Biopharma
NCT02864498
Tralokinumab Monotherapy for Adolescent Subjects With Moderate to Severe Atopic Dermatitis - ECZTRA 6 (ECZema TRAlokinumab Trial no. 6).
LEO Pharma
NCT03526861
Team-Based Connected Health (TCH) to Improve Clinical Outcomes and Access in Atopic Dermatitis
University of Southern California
NCT03981926
A Study of Lebrikizumab (LY3650150) in Participants With Moderate-to-Severe Atopic Dermatitis
Eli Lilly and Company
NCT03443024
A Phase 2 Study of CIM331 for Atopic Dermatitis Patients
Chugai Pharmaceutical
NCT01986933
A Study to Evaluate the Efficacy, and Safety Study of Ruxolitinib Cream in Adults With Moderate Atopic Dermatitis
Incyte Corporation
NCT06238817
A 32-week Trial to Evaluate the Efficacy and Safety of Tralokinumab in Subjects With Moderate-to-severe Atopic Hand Eczema Who Are Candidates for Systemic Therapy
LEO Pharma
NCT05958407
Safety and Efficacy of Lebrikizumab (LY3650150) in Combination With Topical Corticosteroid in Moderate-to-Severe Atopic Dermatitis.
Eli Lilly and Company
NCT04250337
A Study Assessing Rocatinlimab on Vaccine Antibody Response in Moderate-to-severe Atopic Dermatitis (AD) (ROCKET - VOYAGER)
Amgen
NCT05899816
Study to Assess the Safety and Efficacy of Lebrikizumab (LY3650150) in Adolescent Participants With Moderate-to-Severe Atopic Dermatitis
Eli Lilly and Company
NCT04250350
Preliminary Study of Safety and Efficacy of Nanocrystalline Silver Cream in Atopic Dermatitis (Eczema)
Nucryst Pharmaceuticals
NCT00076375
Tradipitant in Treatment-resistant Pruritus Associated With Atopic Dermatitis
Vanda Pharmaceuticals
NCT02651714
An Evaluation of PDI-192 0.1% in Comparison to PDI-192 0.15% in the Treatment of Mild to Moderate Atopic Dermatitis
PreCision Dermatology
NCT01826461
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 18 |
| Phase 2 | 48 |
| Phase 3 | 28 |
| Phase 4 | 19 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Atopic Dermatitis Trial Landscape
ClinicalTrials.gov lists 151 US studies indexed under Atopic Dermatitis, and 55 of those are currently open to recruitment — roughly 36% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Atopic Dermatitis shows 47 late-stage studies (Phase 3 and Phase 4 combined) alongside 66 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Atopic Dermatitis is led by Pfizer with 10 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 100 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Atopic Dermatitis?
PlainTrial tracks 151 US clinical trials for Atopic Dermatitis, of which 55 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Atopic Dermatitis?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.