Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

2026 data Public-data reference. official source

Atopic Dermatitis

Open-data reference.

151 US clinical trials · 55 currently recruiting

Active & Recent Trials

RECRUITING 20,000 participants

Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives

Sanguine Biosciences

NCT05635266

RECRUITING 5,621 participants

An Observational Retrospective Cohort Study Being Conducted in Women With Atopic Dermatitis Exposed to Ruxolitinib Cream Versus Topical Corticosteroids During Pregnancy: A US Claims Database Analysis

Incyte Corporation

NCT06627335

RECRUITING 3,930 participants

An Observational Retrospective Cohort Study Being Conducted in Women With Atopic Dermatitis (AD)

Regeneron Pharmaceuticals

NCT03936335

RECRUITING 1,800 participants

Natural History and Genetics of Food Allergy and Related Conditions

National Institute of Allergy and Infectious Diseases (NIAID)

NCT02504853

RECRUITING 1,500 participants

CorEvitas International Adolescent Atopic Dermatitis (AD) Drug Safety and Effectiveness Registry

CorEvitas

NCT06238765

RECRUITING 1,000 participants

This Study is a Non-interventional Disease Registry of Adolescent and Adult Patients With Atopic Dermatitis Who Initiate or Switch Any Systemic Treatment

Sanofi

NCT07290803

RECRUITING 1,000 participants

Real-world Experience Using Nemolizumab in the Treatment of Moderate-to-Severe Atopic Dermatitis in Adolescents & Adults

Galderma R&D

NCT06988605

RECRUITING 958 participants

Study to Compare Maternal, Fetal, and Infant Outcomes of Women With Mild to Moderate Atopic Dermatitis Exposed to Ruxolitinib Cream During Pregnancy With an Unexposed Control Population

Incyte Corporation

NCT06259669

RECRUITING 900 participants

Monitoring Pregnancy and Infant Outcomes Following Tralokinumab Exposure During Pregnancy in the US and Canada - PROTECT

University of California, San Diego

NCT05938478

RECRUITING Phase 3 675 participants

A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis

AbbVie

NCT06461897

RECRUITING 530 participants

Studies of Skin Microbes in Healthy People and in People With Skin Conditions

National Human Genome Research Institute (NHGRI)

NCT00605878

RECRUITING Phase 3 500 participants

A Long-term Study of the Medicine Called Abrocitinib in Children Aged 2 Years and Older With Moderate to Severe Eczema

Pfizer

NCT06807281

RECRUITING 400 participants

Registry for Systemic Eczema Treatments

Johns Hopkins University

NCT06136767

RECRUITING 400 participants

A Study of How Safe Abrocitinib (CIBINQO) is in Pregnant Women and Their Offspring

Pfizer

NCT05721937

RECRUITING Phase 2 350 participants

A Long-term Safety and Efficacy Study Evaluating APG777 in Atopic Dermatitis

Apogee Therapeutics

NCT07003425

RECRUITING Phase 2 340 participants

A Study To Learn About Two Study Medicines (PF-07275315 And PF-07264660) In People Who Have Moderate To Severe Atopic Dermatitis

Pfizer

NCT05995964

RECRUITING 300 participants

Metabolic Profiling of Immune Responses in Immune-mediated Diseases

National Institute of Allergy and Infectious Diseases (NIAID)

NCT04864886

RECRUITING 240 participants

Skin Microbial Ecology in Atopic Dermatitis

University of Rochester

NCT04170244

RECRUITING Phase 3 240 participants

A Study to Assess the Efficacy and Safety of Ruxolitinib Cream in Children and Adolescents (6 to <18 Years Old) With Moderate Atopic Dermatitis

Incyte Corporation

NCT06832618

RECRUITING Phase 2 224 participants

Platform Study to Evaluate the Efficacy and Safety of Investigational Compound(s) in Patients With Moderate to Severe Atopic Dermatitis

Novartis Pharmaceuticals

NCT06947993

RECRUITING Phase 2 220 participants

A Study to Evaluate the Efficacy and Safety of IMG-007 in Adult Participants With Moderate-to-Severe Atopic Dermatitis

Inmagene

NCT07037901

RECRUITING Phase 4 200 participants

A Study to See How Well Lebrikizumab Works in Adults and Adolescents With Moderate Atopic Dermatitis (Eczema) and High Itch Burden

Eli Lilly and Company

NCT07006792

RECRUITING NA 200 participants

Michigan Food and Atopic Dermatitis (M-FAD) Program - Molecular Analytics Project

University of Michigan

NCT06300697

RECRUITING 200 participants

Blood, Urine, and Tissue Collection for Cutaneous Lymphoma, Eczema, and Atopic Dermatitis Research

University of Pittsburgh

NCT00177268

RECRUITING Phase 2 200 participants

Study to Evaluate Soquelitinib in Participants With Moderate to Severe AD

Corvus Pharmaceuticals

NCT07441395

RECRUITING Phase 2 200 participants

A Study of KT-621 Administered Orally to Participants With Moderate to Severe Atopic Dermatitis

Kymera Therapeutics

NCT07217015

RECRUITING Phase 3 200 participants

A Study of Upadacitinib in Adult Participants With Moderate-to-Severe Atopic Dermatitis and Inadequate Response to Dupilumab

AbbVie

NCT06389136

RECRUITING Phase 1 198 participants

A Study of BBT001 in Healthy Volunteers (HVs) and in Adult Patients With Atopic Dermatitis (AD)

Bambusa Therapeutics

NCT06808477

RECRUITING Phase 3 195 participants

A Trial to Evaluate the Efficacy and Safety of Tralokinumab in Combination With Topical Corticosteroids in Children and Infants With Moderate-to-severe Atopic Dermatitis

LEO Pharma

NCT06311682

RECRUITING Phase 3 180 participants

A Study to Investigate Safety and Efficacy of Tapinarof Cream, 1% in Participants Ages 3 Months to < 24 Months With Atopic Dermatitis

Organon and

NCT07265479

RECRUITING Phase 2 160 participants

A Study to Assess the Efficacy and Safety of Afimkibart (RO7790121) in Participants With Moderate to Severe Atopic Dermatitis

Hoffmann-La Roche

NCT06863961

RECRUITING Phase 2 160 participants

A Dose-ranging Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Galvokimig in Adult Study Participants With Atopic Dermatitis

UCB Biopharma SRL

NCT07277660

RECRUITING 150 participants

Real World Efficiency of Abrocitinib Treatment at Patients With Moderate to Severe Atopic Dermatitis Who Had Inadequate Response to Previous Biologic Therapies.

Pfizer

NCT06899204

RECRUITING Phase 2 120 participants

Cardamom and Topical Roseomonas in Atopic Dermatitis

National Institute of Allergy and Infectious Diseases (NIAID)

NCT06096857

RECRUITING Phase 2 120 participants

A Long Term Extension Study to Evaluate the Safety and Efficacy of Afimkibart (RO7790121) in Participants With Atopic Dermatitis

Hoffmann-La Roche

NCT07223697

RECRUITING Phase 1 119 participants

FIH Study to Evaluate the Tolerability of PF-07832837 in Healthy Adults and Patients

Pfizer

NCT06564389

RECRUITING 111 participants

Mechanisms of Increased Disease Severity in AD Patients With the IL-4Ra R576 Polymorphism

Boston Children's Hospital

NCT04455906

RECRUITING Phase 2 100 participants

A Study to Assess the Efficacy of GX-03 in Moderate to Severe Eczema (Atopic Dermatitis)

Turn Therapeutics

NCT07355075

RECRUITING Phase 2 96 participants

ATI-045 Versus Placebo in Patients With Moderate-to-Severe Atopic Dermatitis

Aclaris Therapeutics

NCT07011706

RECRUITING Phase 2 90 participants

Evaluate Efficacy and Safety of Repeat Subcutaneous Doses of FB825 in Adults With Moderate-to-Severe Atopic Dermatitis

Oneness Biotech Co.

NCT06397911

RECRUITING Phase 2 90 participants

A Study Evaluating TRIV-509 in Atopic Dermatitis

Triveni Bio

NCT07167758

RECRUITING 90 participants

Sodium in the Skin and Atopic Dermatitis

University of California, San Francis

NCT06998446

RECRUITING Phase 1 86 participants

Targeted Investigation of Microbiome 2 Treat Atopic Dermatitis (TIME-2)

National Institute of Allergy and Infectious Diseases (NIAID)

NCT06504160

RECRUITING Phase 2 84 participants

Phase 2a Study to Assess the Efficacy,Safety and Tolerability of GIA632 in Adult Participants With Moderate to Severe Atopic Dermatitis

Novartis Pharmaceuticals

NCT07220577

RECRUITING Phase 2 60 participants

A Study to Assess Molecular Changes in Adult Participants With Moderate to Severe Hidradenitis Suppurativa or With Moderate to Severe Atopic Dermatitis Receiving Subcutaneous Injections of Lutikizumab

AbbVie

NCT06524635

RECRUITING Phase 2 56 participants

Treatment of Atopic Dermatitis and Alopecia Areata With Abrocitinib in Individuals With Down Syndrome

Icahn School of Medicine at Mount Sinai

NCT07242638

RECRUITING Phase 4 48 participants

Lebrikizumab in Moderate-to-severe Atopic Dermatitis

Johann E Gudjonsson MD PhD

NCT06906497

RECRUITING Phase 1 45 participants

A Study to Investigate the Safety, Tolerability, and Efficacy of BxC-I17e Single and Multiple Dose SC Injection in Patients With Moderate to Severe Atopic Dermatitis

Brexogen

NCT06055361

RECRUITING Phase 4 40 participants

Using Dupilumab to Improve Circadian Function, Sleep and Pruritus in Children With Moderate/Severe Atopic Dermatitis

Northwestern University

NCT05042258

RECRUITING Phase 4 40 participants

Dupixent and Narrowband UVB for Atopic Dermatitis

Psoriasis Treatment Center of Central New Jersey

NCT05285839

RECRUITING Phase 4 30 participants

Ethnic Differences in Mechanisms of Action of Dupilumab

University of Michigan

NCT05268107

RECRUITING NA 30 participants

Topical Treatment for Atopic Dermatitis

Wake Forest University Health Sciences

NCT06244212

RECRUITING Phase 4 30 participants

Dupilumab De-escalation in Pediatric Atopic Dermatitis

Johns Hopkins University

NCT06116526

RECRUITING Phase 1 20 participants

Evaluating the Safety and Tolerability of Baricitinib in Patients With Job Syndrome With Lupus-Like Disease and/or Atopic Dermatitis

National Institute of Allergy and Infectious Diseases (NIAID)

NCT07262983

RECRUITING Phase 4 15 participants

Molecular Signatures of Cutaneous Dupilumab Response

University of California, San Francis

NCT05858619

ACTIVE NOT RECRUITING 15,000 participants

A Longitudinal Observational Study of Patients Undergoing Therapy for IMISC

Target PharmaSolutions

NCT03661866

ACTIVE NOT RECRUITING 8,000 participants

10 Year Registry of Children (Ages 2-17 Years) With Eczema That Have Used Pimecrolimus

Bausch Health Americas

NCT00568997

ACTIVE NOT RECRUITING Phase 3 2,621 participants

A Study to Assess Long-term Safety, Tolerability, and Efficacy of Rocatinlimab in Adult and Adolescent Participants With Moderate-to-severe Atopic Dermatitis (AD)

Amgen

NCT05882877

ACTIVE NOT RECRUITING 2,500 participants

Systems Biology of Early Atopy

National Institute of Allergy and Infectious Diseases (NIAID)

NCT04798079

ACTIVE NOT RECRUITING Phase 3 1,533 participants

A Study to Evaluate Upadacitinib in Combination With Topical Corticosteroids in Adolescent and Adult Participants With Moderate to Severe Atopic Dermatitis

AbbVie

NCT03568318

ACTIVE NOT RECRUITING Phase 3 880 participants

Study to Assess the Long-term Safety of Dupilumab Administered in Participants ≥6 Months to <18 Years of Age With Atopic Dermatitis (AD)

Regeneron Pharmaceuticals

NCT02612454

ACTIVE NOT RECRUITING 505 participants

Defining the Skin and Blood Biomarkers of Pediatric Atopic Dermatitis

Northwestern University

NCT01782703

ACTIVE NOT RECRUITING Phase 2 470 participants

A Study Evaluating APG777 in Atopic Dermatitis

Apogee Therapeutics

NCT06395948

ACTIVE NOT RECRUITING Phase 2 398 participants

Seal, Stopping Eczema and Allergy Study

Kari Nadeau, MD, PhD

NCT03742414

ACTIVE NOT RECRUITING Phase 3 367 participants

A Study of Lebrikizumab (LY3650150) in Participants 6 Months to <18 Years of Age With Moderate-to-Severe Atopic Dermatitis

Eli Lilly and Company

NCT05559359

ACTIVE NOT RECRUITING Phase 2 210 participants

Phase 2 Trial of HY209gel in Atopic Dermatitis Patients

Shaperon

NCT06024499

ACTIVE NOT RECRUITING Phase 2 200 participants

A Study to Learn About Study Medicine Called PF-08049820 in People With Eczema

Pfizer

NCT07216027

ACTIVE NOT RECRUITING Phase 3 151 participants

A Study With Self-administered Rocatinlimab in Adolescent and Adult Participants With Moderate-to-severe Atopic Dermatitis

Amgen

NCT06224192

ACTIVE NOT RECRUITING Phase 2 131 participants

A Study of Barzolvolimab in Patients With Atopic Dermatitis

Celldex Therapeutics

NCT06727552

ACTIVE NOT RECRUITING Phase 2 102 participants

Evaluating Safety and Efficacy of ADX-914 in Patients With Moderate to Severe Atopic Dermatitis (SIGNAL-AD)

Q32 Bio

NCT05509023

ACTIVE NOT RECRUITING Phase 2 83 participants

A Study to Evaluate the Effectiveness and Safety of Treatments, Either Alone or in Combination, for the Treatment of Moderate to Severe Atopic Dermatitis

AbbVie

NCT06718101

ACTIVE NOT RECRUITING Phase 4 20 participants

Tralokinumab for Dupilumab Failures

Psoriasis Treatment Center of Central New Jersey

NCT06773455

ACTIVE NOT RECRUITING Phase 1 16 participants

A Study to Learn If the Study Medicine Called PF-08049820 Changes How the Body Processes the Other Study Medicines Called Oral Contraceptives, Midazolam, and Dabigatran in Healthy Adult Female Participants

Pfizer

NCT07190430

ACTIVE NOT RECRUITING Phase 4 15 participants

Bodewell Products for the Treatment of Atopic Dermatitis

University of Alabama at Birmingham

NCT05566262

COMPLETED NA 943 participants

Asthma and Atopic Dermatitis Validation of PROMIS Pediatric Instruments

Northwestern University

NCT03051347

COMPLETED Phase 3 912 participants

Evaluation of Upadacitinib in Adolescent and Adult Patients With Moderate to Severe Atopic Dermatitis (Eczema)

AbbVie

NCT03569293

COMPLETED Phase 3 746 participants

A Study Assessing Rocatinlimab in Combination With Topical Corticosteroid and/or Topical Calcineurin Inhibitors in Adult Participants With Moderate-to-severe Atopic Dermatitis (AD)

Amgen

NCT05724199

COMPLETED Phase 3 740 participants

Study to Assess the Efficacy and Long-term Safety of Dupilumab (REGN668/SAR231893) in Adult Participants With Moderate-to-Severe Atopic Dermatitis

Regeneron Pharmaceuticals

NCT02260986

COMPLETED Phase 3 726 participants

A Study Assessing Rocatinlimab (AMG 451) Monotherapy in Moderate-to-severe Atopic Dermatitis (AD) (ROCKET-Horizon)

Amgen

NCT05651711

COMPLETED Phase 2 547 participants

B244 Topical Spray for the Treatment of Pruritus in Adults With a History of Atopic Dermatitis

AOBiome

NCT04490109

COMPLETED Phase 3 532 participants

A Study to Evaluate Rocatinlimab (AMG 451) in Adolescent Participants With Moderate-to-severe Atopic Dermatitis (AD)

Amgen

NCT05704738

COMPLETED Phase 3 445 participants

Evaluation of the Efficacy and Safety of Lebrikizumab (LY3650150) in Moderate to Severe Atopic Dermatitis

Eli Lilly and Company

NCT04178967

COMPLETED Phase 3 424 participants

Evaluation of the Efficacy and Safety of Lebrikizumab (LY3650150) in Moderate to Severe Atopic Dermatitis (ADvocate1)

Eli Lilly and Company

NCT04146363

COMPLETED 409 participants

Impact of the Severity of Pediatric Psoriasis on Childhood Body Mass Index

Northwestern University

NCT00879944

COMPLETED Phase 3 407 participants

Tapinarof for the Treatment of Atopic Dermatitis in Children and Adults

Organon and

NCT05014568

COMPLETED Phase 3 406 participants

Tapinarof for the Treatment of Atopic Dermatitis in Children and Adults (DMVT-505-3102)

Organon and

NCT05032859

COMPLETED Phase 2 380 participants

Study of Dupilumab Administered to Adult Patients With Moderate-to-Severe Atopic Dermatitis

Regeneron Pharmaceuticals

NCT01859988

COMPLETED Phase 2 321 participants

Efficacy and Safety Study of Orally Administered DS107 in Moderate to Severe Atopic Dermatitis Patients

DS Biopharma

NCT02864498

COMPLETED Phase 3 301 participants

Tralokinumab Monotherapy for Adolescent Subjects With Moderate to Severe Atopic Dermatitis - ECZTRA 6 (ECZema TRAlokinumab Trial no. 6).

LEO Pharma

NCT03526861

COMPLETED NA 300 participants

Team-Based Connected Health (TCH) to Improve Clinical Outcomes and Access in Atopic Dermatitis

University of Southern California

NCT03981926

COMPLETED Phase 2 280 participants

A Study of Lebrikizumab (LY3650150) in Participants With Moderate-to-Severe Atopic Dermatitis

Eli Lilly and Company

NCT03443024

COMPLETED Phase 2 264 participants

A Phase 2 Study of CIM331 for Atopic Dermatitis Patients

Chugai Pharmaceutical

NCT01986933

COMPLETED Phase 3 241 participants

A Study to Evaluate the Efficacy, and Safety Study of Ruxolitinib Cream in Adults With Moderate Atopic Dermatitis

Incyte Corporation

NCT06238817

COMPLETED Phase 3 235 participants

A 32-week Trial to Evaluate the Efficacy and Safety of Tralokinumab in Subjects With Moderate-to-severe Atopic Hand Eczema Who Are Candidates for Systemic Therapy

LEO Pharma

NCT05958407

COMPLETED Phase 3 228 participants

Safety and Efficacy of Lebrikizumab (LY3650150) in Combination With Topical Corticosteroid in Moderate-to-Severe Atopic Dermatitis.

Eli Lilly and Company

NCT04250337

COMPLETED Phase 3 221 participants

A Study Assessing Rocatinlimab on Vaccine Antibody Response in Moderate-to-severe Atopic Dermatitis (AD) (ROCKET - VOYAGER)

Amgen

NCT05899816

COMPLETED Phase 3 206 participants

Study to Assess the Safety and Efficacy of Lebrikizumab (LY3650150) in Adolescent Participants With Moderate-to-Severe Atopic Dermatitis

Eli Lilly and Company

NCT04250350

COMPLETED Phase 2 180 participants

Preliminary Study of Safety and Efficacy of Nanocrystalline Silver Cream in Atopic Dermatitis (Eczema)

Nucryst Pharmaceuticals

NCT00076375

COMPLETED Phase 2 168 participants

Tradipitant in Treatment-resistant Pruritus Associated With Atopic Dermatitis

Vanda Pharmaceuticals

NCT02651714

COMPLETED Phase 2 151 participants

An Evaluation of PDI-192 0.1% in Comparison to PDI-192 0.15% in the Treatment of Mild to Moderate Atopic Dermatitis

PreCision Dermatology

NCT01826461

Phase Distribution

PhaseTrial count
Early Phase 1 18
Phase 2 48
Phase 3 28
Phase 4 19

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Atopic Dermatitis Trial Landscape

ClinicalTrials.gov lists 151 US studies indexed under Atopic Dermatitis, and 55 of those are currently open to recruitment — roughly 36% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Atopic Dermatitis shows 47 late-stage studies (Phase 3 and Phase 4 combined) alongside 66 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Atopic Dermatitis is led by Pfizer with 10 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 100 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Atopic Dermatitis?

PlainTrial tracks 151 US clinical trials for Atopic Dermatitis, of which 55 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Atopic Dermatitis?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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