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Acute Respiratory Failure clinical trials
5 of 14 indexed Acute Respiratory Failure trials are currently recruiting.
14 US clinical trials · 5 currently recruiting
Acute Respiratory Failure is the subject of 14 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. The most active sponsor is Barnes-Jewish Hospital, running 1 of these trials.
The research picture
Acute Respiratory Failure has 14 registered US clinical trials, 5 of them open to new participants right now, about 36% of the total.
- 5
- recruiting participants now
- 36%
- of trials open to enrollment
- 0
- in Phase 3–4 (later-stage)
- 1
- top sponsor: Barnes-Jewish Hospital
Active & Recent Trials
14 total, page 1 of 1
Waveform Capnography Compared to Colorimetric Carbon Dioxide Detection During Tracheal Intubation of Critically Ill Adults
Brian Driver
NCT06934876
Simulation Trial of Telemedical Support for Paramedics
Boston Medical Center
NCT06441760
Investigating Dyadic Expectations About ARF Survivorship (IDEAS)
Johns Hopkins University
NCT06401239
Blue Protocol and Eko Artificial Intelligence Are Best (BEA-BEST)
University of Louisville
NCT05144633
Virtual Reality in ICU - PARTNER
Kirby Mayer
NCT06876168
The Maximizing Extubation Outcomes Through Educational and Organizational Research (METEOR) Trial
University of Pittsburgh
NCT05523479
Study of Therapeutic Exercise in Acute Respiratory Failure to Improve Neuromuscular Disability Trial
University of Pennsylvania
NCT03863470
Bougie or Stylet In Patients Undergoing Intubation Emergently (BOUGIE)
Vanderbilt University Medical Center
NCT03928925
Imputation of PaO2 From SaO2
Brigham and Women's Hospital
NCT02598492
High Flow Therapy for the Treatment of Respiratory Failure in the ED
Vapotherm
NCT02236559
Treatment of Critical Illness Polyneuromyopathy
University of Colorado, Denver
NCT01058421
High-Flow Oxygen Therapy Following Tracheostomy
Barnes-Jewish Hospital
NCT03721419
Novel Arm Restraint For Critically Ill Patients To Reduce Immobility, Sedation, Agitation and Cognitive Impairment
University of Vermont
NCT04067622
Feasibility of Upright Bed Position in ARDS Patients
Wake Forest University Health Sciences
NCT02160561
Phase Distribution
Phase data not available
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Acute Respiratory Failure Trial Landscape
14 indexed Acute Respiratory Failure studies · 5 recruiting (36%).
Phase mix: 0 late (III/IV) vs 0 early (I/II).
Top sponsor: Barnes-Jewish Hospital (1 trial), 9 others listed. 14 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Acute Respiratory Failure?
PlainTrial tracks 14 US clinical trials for Acute Respiratory Failure, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Acute Respiratory Failure?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.