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ClinicalTrials.gov 5 recruiting now official registry

Acute Respiratory Failure clinical trials

5 of 14 indexed Acute Respiratory Failure trials are currently recruiting.

14 US clinical trials · 5 currently recruiting

Acute Respiratory Failure is the subject of 14 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. The most active sponsor is Barnes-Jewish Hospital, running 1 of these trials.

The research picture

Acute Respiratory Failure has 14 registered US clinical trials, 5 of them open to new participants right now, about 36% of the total.

5
recruiting participants now
36%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
1
top sponsor: Barnes-Jewish Hospital

Active & Recent Trials

14 total, page 1 of 1

RECRUITING 1,332 participants

Waveform Capnography Compared to Colorimetric Carbon Dioxide Detection During Tracheal Intubation of Critically Ill Adults

Brian Driver

NCT06934876

RECRUITING NA 420 participants

Simulation Trial of Telemedical Support for Paramedics

Boston Medical Center

NCT06441760

RECRUITING 235 participants

Investigating Dyadic Expectations About ARF Survivorship (IDEAS)

Johns Hopkins University

NCT06401239

RECRUITING 100 participants

Blue Protocol and Eko Artificial Intelligence Are Best (BEA-BEST)

University of Louisville

NCT05144633

RECRUITING 32 participants

Virtual Reality in ICU - PARTNER

Kirby Mayer

NCT06876168

ACTIVE NOT RECRUITING NA 13,018 participants

The Maximizing Extubation Outcomes Through Educational and Organizational Research (METEOR) Trial

University of Pittsburgh

NCT05523479

COMPLETED NA 1,917 participants

Study of Therapeutic Exercise in Acute Respiratory Failure to Improve Neuromuscular Disability Trial

University of Pennsylvania

NCT03863470

COMPLETED NA 1,106 participants

Bougie or Stylet In Patients Undergoing Intubation Emergently (BOUGIE)

Vanderbilt University Medical Center

NCT03928925

COMPLETED 646 participants

Imputation of PaO2 From SaO2

Brigham and Women's Hospital

NCT02598492

COMPLETED NA 204 participants

High Flow Therapy for the Treatment of Respiratory Failure in the ED

Vapotherm

NCT02236559

COMPLETED NA 120 participants

Treatment of Critical Illness Polyneuromyopathy

University of Colorado, Denver

NCT01058421

COMPLETED NA 61 participants

High-Flow Oxygen Therapy Following Tracheostomy

Barnes-Jewish Hospital

NCT03721419

COMPLETED NA 58 participants

Novel Arm Restraint For Critically Ill Patients To Reduce Immobility, Sedation, Agitation and Cognitive Impairment

University of Vermont

NCT04067622

COMPLETED NA 10 participants

Feasibility of Upright Bed Position in ARDS Patients

Wake Forest University Health Sciences

NCT02160561

Phase Distribution

Phase data not available

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Acute Respiratory Failure Trial Landscape

14 indexed Acute Respiratory Failure studies · 5 recruiting (36%).

Phase mix: 0 late (III/IV) vs 0 early (I/II).

Top sponsor: Barnes-Jewish Hospital (1 trial), 9 others listed. 14 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Acute Respiratory Failure?

PlainTrial tracks 14 US clinical trials for Acute Respiratory Failure, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Acute Respiratory Failure?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.