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RECRUITING Phase 3

Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)

NCT07252232 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to evaluate the safety and efficacy of a novel RAS(ON) inhibitor compared to standard of care (SOC) observation only.

Interventions

  • DRUG daraxonrasib

Study Locations (7)

Connecticut

  • Hartford Healthcare — Hartford

Indiana

  • Community Health Network — Indianapolis

Missouri

  • Saint Luke's Cancer Institute — Kansas City

Ohio

  • Taylor Cancer Research Center — Maumee

South Dakota

  • Avera Cancer Institute — Sioux Falls

Virginia

  • Virginia Cancer Specialists — Fairfax

Puerto Rico

  • Pan American Oncology Trials, LLC — San Juan

Trial Details

FieldValue
Enrollment Target 500 participants
Start Date 2025-12-15
Est. Completion 2030-07-10
Phase Phase 3

Sponsor

Revolution Medicines

66 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07252232

The ClinicalTrials.gov registry entry for NCT07252232 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 500 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Revolution Medicines, which has 66 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 5 conditions, with Pancreatic Cancer appearing as the primary indexed condition, and to 1 intervention — of which daraxonrasib is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT07252232 reports 7 study locations spanning 7 distinct geographic areas — top geographies include Connecticut, Indiana, Missouri. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT07252232 about?

NCT07252232 is a clinical study titled "Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)". The purpose of this study is to evaluate the safety and efficacy of a novel RAS(ON) inhibitor compared to standard of care (SOC) observation only.

What is the current status of trial NCT07252232?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 500 participants. The study started on 2025-12-15. Estimated completion is 2030-07-10.

What conditions does trial NCT07252232 study?

This clinical trial studies the following conditions: Pancreatic Cancer, PDAC - Pancreatic Ductal Adenocarcinoma, PDAC, Resectable Pancreatic Ductal Adenocarcinoma (PDAC), Resected Pancreatic Adenocarcinoma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT07252232?

The interventions under investigation include: daraxonrasib (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT07252232?

This trial is sponsored by Revolution Medicines, which has 66 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT07252232 being conducted?

This trial has 7 study locations across Connecticut, Indiana, Missouri, Ohio, South Dakota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial