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Obstructive Sleep Apnea: early-phase trial registry
66 of 157 indexed Obstructive Sleep Apnea trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #70 of 28,707 conditions by registered trial count.
157 US clinical trials · 66 currently recruiting · #70 of 28,707 conditions by registered trial count
Obstructive Sleep Apnea: 157 US clinical trials tracked, 66 recruiting.
Obstructive Sleep Apnea is the subject of 157 registered US clinical trials on ClinicalTrials.gov, 66 of them currently open to new participants. 11 are in Phase 3-4 (later-stage) and 26 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 11 of these trials.
Enrollment posture brief
Registry condition obstructive-sleep-apnea
OPEN 66 | RECR 42% | LATE 11 | EARLY 26 | RANK #70 | SPON 11
Volume-matched condition peers
Nearest open-share peer: Anesthesia, Local (42% recruiting · 19 trials)
Obstructive Sleep Apnea lists 66 open slots (42% of 157 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Obstructive Sleep Apnea on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Obstructive Sleep Apnea is recruiting above its size-band peers.
66 of 157 indexed trials (42%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Obstructive Sleep Apnea trials is spread across many organizations.
VA Office of Research and Development accounts for 11 of 157 trials (7%). 96 distinct sponsors appear on at least one study for this condition label.
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Typical Obstructive Sleep Apnea enrolment sits around 76 participants.
Median target enrolment is 76 among the 156 trials that report a genuine target (sentinel values excluded). 85 of those (54.5%) plan for fewer than 100 participants.
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Obstructive Sleep Apnea research is mostly interventional.
123 interventional and 34 observational studies make up this index (78.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
157 total, page 2 of 4
Community Health Advocates for Motivating PAP Use in Our Neighborhoods.
University of Miami
NCT06047353
App-Based Optimization of Long-Term CPAP Adherence and Quality of Life
Mayo Clinic
NCT06381115
Mild Intermittent Hypoxia and Its Multipronged Effect on Sleep Apnea
Wayne State University
NCT03736382
Self-Supporting Nasopharyngeal Airway (ssNPA) Treating Upper Airway Obstruction in Hypotonia
University of Michigan
NCT05527652
Whole Food Plant-based Diet Effect on Obstructive Sleep Apnea
Mayo Clinic
NCT06395181
Mandibular Advancement Device and Changes in Nocturia
Fernanda Yanez Regonesi
NCT05562388
Medications for Obstructive Sleep Apnea to Improve Cognition in Children With Down Syndrome
University of Arizona
NCT05933603
Metabolic Endpoints for Obstructive Sleep Apnea Following Twelfth Cranial Nerve Stimulation
University of Chicago
NCT06317701
Reducing Obstructive Sleep Apnea After Hypoglossal Nerve Stimulation Through Mandibular Advancement
Washington University School of Medicine
NCT07132307
Smart Pillows for Enhancing Sleep Quality
Indiana University
NCT06594627
Obstructive Sleep Apnea Therapeutic Intervention for REsiDual Sleepiness
NYU Langone Health
NCT06698809
Preliminary Evaluation of a RCMP to Predict Failure of Maxillomandibular Advancement Surgery for OSA
University of Michigan
NCT03929549
Trazodone on OSA Endotypes
Brigham and Women's Hospital
NCT06286189
Atomoxetine and DAW2022 on OSA Severity
Brigham and Women's Hospital
NCT05350215
Pharmacological Activation of HMN for OSA Aim 2
Brigham and Women's Hospital
NCT03858751
Magnetic Apnea Prevention(MAGNAP) Device to Treat Obstructive Sleep Apnea:First-In-Human Study of Feasibility and Safety
Michael Harrison
NCT02431507
A Prospective Observational Cohort to Study the Genetics of Obstructive Sleep Apnea and Associated Co-Morbidities
Ulysses Magalang MD
NCT01857427
A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight
Eli Lilly and Company
NCT05929066
A Study of Retatrutide (LY3437943) in Participants With Type 2 Diabetes Mellitus Who Have Obesity or Overweight
Eli Lilly and Company
NCT05929079
RePOSA-Revealing the Efficacy of IHL-42X Use in Patients With OSA
Incannex Healthcare
NCT06146101
Predictors of De-novo Development of Obstructive Sleep Apnea in Pregnancy
The Miriam Hospital
NCT02917876
Obstructive Sleep Apnea in Survivors of Hodgkin Lymphoma Treated With Thoracic Radiation
St. Jude Children's Research Hospital
NCT03361020
Novel physIologiC prEdictors of Positive Airway Pressure Effectiveness
Yale University
NCT05067088
Positive Airway Pressure, Sleep Apnea, and the Placenta (PAP-SAP)
The Miriam Hospital
NCT02412696
Treating Obstructive Sleep Apnea Using Targeted Hypoglossal Neurostimulation
LivaNova
NCT04950894
Inspire® Post-Approval Study / Protocol Number 2014-001
Inspire Medical Systems
NCT02413970
Breathing Training for Improving Cardiovascular Health in Older Adults With Sleep Apnea
University of Arizona
NCT04932447
Post-Operative Steroids After Sleep Surgery
Medical University of South Carolina
NCT06818981
Dual-sided Hypoglossal neRvE stimulAtion for the treatMent of Obstructive Sleep Apnea (DREAM)
Nyxoah S.A.
NCT03868618
Validation of Sleep Questionnaires in the Down Syndrome Population
Oregon Health and Science University
NCT03771469
Adherence to Health Coaching with Wearable Devices: Enhancing Patient Engagement and Outcomes
Coastal Carolina University
NCT06525337
Effects of Hypoglossal Nerve Stimulation on Cognition and Language in Down Syndrome and Obstructive Sleep Apnea
Inspire Medical Systems
NCT04801771
RPMO2 Oximeter Accuracy During Sleep 1 Trial
ProSomnus Sleep Technologies
NCT07397780
Restoring Metabolic and Reproductive Health With Sleep in PCOS Study, CPAP Trial
University of California, San Francisco
NCT05920694
3D Printer Modified CPAP Mask for Obstructive Sleep Apnea
Beth Israel Deaconess Medical Center
NCT03932383
Obstructive Sleep Apnea (OSA) and Sex-Specific Responses to N-acetylcysteine (NAC)
NYU Langone Health
NCT06311045
Addressing Sleep Apnea Post-Stroke/TIA
VA Office of Research and Development
NCT04322162
Impact of Automated Education and Follow-up Mechanisms on Patient Engagement
Kaiser Permanente
NCT02279901
World Trade Center (WTC) CHEST
Icahn School of Medicine at Mount Sinai
NCT01466218
Asthma and Obstructive Sleep Apnea (OSA)
University of Wisconsin, Madison
NCT01026298
World Trade Center Kidney-Link
Icahn School of Medicine at Mount Sinai
NCT03234530
"Twelve-week Study of the Safety and Efficacy of JZP-110 in the Treatment of Excessive Sleepiness in OSA"
Jazz Pharmaceuticals
NCT02348606
Improving the Frequency and Quality of Sleep Apnea Care Management
VA Office of Research and Development
NCT01916655
Obstructive Sleep Apnea in World Trade Center Responders
Rutgers, The State University of New Jersey
NCT01753999
Evaluation of Obstructive Sleep Apnea as a Risk Factor for Pulmonary Embolism
Atlantic Health System
NCT00409045
Self-Management of Continuous Positive Airway Pressure Settings
VA Office of Research and Development
NCT03536572
A Research Study for Children About Heart Changes and Obstructive Sleep Apnea (OSA)
Children's Hospital Medical Center, Cincinnati
NCT01837459
Patient Perception Questionnaire Validation
Fisher and Paykel Healthcare
NCT02067000
Development and Validation of Pediatric Narcolepsy Patient Reported Outcomes Scale
Boston Children's Hospital
NCT05373979
TipTraQ Home Sleep Test Validation Study, Duke
PranaQ Pte.
NCT06351878
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 12 |
| Phase 2 | 14 |
| Phase 3 | 8 |
| Phase 4 | 3 |
Top Sponsors
Named interventions
Most-linked intervention names on Obstructive Sleep Apnea records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Obstructive Sleep Apnea trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Obstructive Sleep Apnea page
157 registered trials, 66 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 66 Obstructive Sleep Apnea trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- VA Office of Research and Development sponsors the most Obstructive Sleep Apnea trials on record, review their full trial history before evaluating a specific study. See VA Office of Research and Development's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Obstructive Sleep Apnea condition card totals 157 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.