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NCT03929549 · ClinicalTrials.gov registry record · NA
Preliminary Evaluation of a RCMP to Predict Failure of Maxillomandibular Advancement Surgery for OSA
A NA study of Obstructive Sleep Apnea and Maxillomandibular Advancement Surgery, sponsored by University of Michigan.
- Recruiting
- Registry status
- NA
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT03929549: Recruiting NA study of Obstructive Sleep Apnea and Maxillomandibular Advancement Surgery, sponsored by University of Michigan.
NCT03929549 is a NA study of Obstructive Sleep Apnea and Maxillomandibular Advancement Surgery that is actively recruiting participants, run by University of Michigan. The registered enrollment target is 20 participants, below the 221-participant average among 155 other Obstructive Sleep Apnea trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03929549, a NA study of Obstructive Sleep Apnea and Maxillomandibular Advancement Surgery, is actively recruiting participants, sponsored by University of Michigan.
- RECRUITING
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
Maxillomandibular advancement (MMA) surgery, one of the most successful surgical procedures for the treatment of obstructive sleep apnea (OSA), is predominantly used to manage patients with moderate to severe OSA. However, limiting factors include incomplete response in some cases, unfavorable facial changes as a result of large advancements, and risk of malocclusion or malunion. This study will be done to determine predictors of success with MMA surgery in patients with moderate to severe OSA. Studies have already shown the value of a remote controlled mandibular positioner (RCMP) device to identify the correct level of therapeutic protrusion needed with oral appliance therapy. Moreover, some patients experience a dose dependent improvement in sleep parameters based on the degree of protrusion during the titration study. Use of RCMP as a means to identify potential candidates for MMA, may help customize treatment options for patients with OSA by providing predictive value.
Primary Outcome
Secondary outcome variable: Failure of MMA surgery defined as AHI ≥ 15/hour
Conditions Studied
Interventions
- DEVICE RCMP titration
Study Locations (1)
Michigan
- Michigan Medicine Oral and Maxillofacial Surgery - Ann Arbor
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2019-08-12 |
| Est. Completion | 2026-07 |
| Phase | NA |
What NCT03929549 shows while recruiting
NCT03929549 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 221-participant average among 155 other Obstructive Sleep Apnea trials with a reported enrollment target (91% lower).
The record links to 2 conditions, with Obstructive Sleep Apnea appearing as the primary indexed condition, and to 1 intervention - of which RCMP titration is the first listed.
NCT03929549 reports a single indexed study location in Michigan.
Frequently Asked Questions
What is clinical trial NCT03929549 about?
NCT03929549 is a clinical study titled "Preliminary Evaluation of a RCMP to Predict Failure of Maxillomandibular Advancement Surgery for OSA". Maxillomandibular advancement (MMA) surgery, one of the most successful surgical procedures for the treatment of obstructive sleep apnea (OSA), is predominantly used to manage patients with moderate to severe OSA. However, limiting factors include incomplete response in some cases, unfavorable facia...
What is the current status of trial NCT03929549?
This trial is currently recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2019-08-12. Estimated completion is 2026-07.
What conditions does trial NCT03929549 study?
This clinical trial studies the following conditions: Obstructive Sleep Apnea, Maxillomandibular Advancement Surgery.
What interventions are being tested in trial NCT03929549?
The interventions under investigation include: RCMP titration (DEVICE).
Who is sponsoring clinical trial NCT03929549?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03929549 being conducted?
This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03929549's enrollment target sits among peer trials
20 140th of 155 higher than 13 of 155 other Obstructive Sleep Apnea trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obstructive Sleep Apnea trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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