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ClinicalTrials.gov 8 recruiting now later-stage tilt small index

Anesthesia, Local: later-stage trial registry

8 of 19 indexed Anesthesia, Local trials are currently recruiting, with more weight in Phase 3-4.

Corpus placement: #902 of 28,707 conditions by registered trial count.

19 US clinical trials · 8 currently recruiting · #902 of 28,707 conditions by registered trial count

Anesthesia, Local: 19 US clinical trials tracked, 8 recruiting.

Anesthesia, Local is the subject of 19 registered US clinical trials on ClinicalTrials.gov, 8 of them currently open to new participants. 9 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is American Genomics, running 2 of these trials.

Enrollment posture brief

Registry condition anesthesia-local

OPEN 8 | RECR 42% | LATE 9 | EARLY 2 | RANK #902 | SPON 2

Nearest open-share peer: Brain Concussion (42% recruiting · 19 trials)

Amyotrophic Lateral Sclerosi52.6%Anesthesia, Local (this)42%Alcohol Consumption36.8%Attention Deficit Hyperactiv26.3%Bacterial Infections15.8%
Open-enrollment share among volume-matched conditions near Anesthesia, Local

Anesthesia, Local lists 8 open slots (42% of 19 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Anesthesia, Local on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Anesthesia, Local is recruiting below its size-band peers.

    8 of 19 indexed trials (42.1%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Anesthesia, Local trials is spread across many organizations.

    American Genomics accounts for 2 of 19 trials (10.5%). 17 distinct sponsors appear on at least one study for this condition label.

  3. Most Anesthesia, Local trials plan to enrol fewer than 100 people.

    Median target enrolment is 61 among the 19 trials that report a genuine target (sentinel values excluded). 14 of those (73.7%) plan for fewer than 100 participants.

  4. Anesthesia, Local research is mostly interventional.

    17 interventional and 2 observational studies make up this index (89.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 12Phase 32Phase 47

Open and recent trials

19 total, page 1 of 1

RECRUITING NA 204 participants

Empathy Through Pain Control: Lidocaine Paracervical Block for IUD Placements

University of California, San Diego

NCT06960317

RECRUITING NA 134 participants

Effect of Fasting on Patient Outcomes After Wide-Awake, Local Anesthesia-only, No Tourniquet (WALANT) Procedures

University of California, Irvine

NCT05819801

RECRUITING NA 80 participants

A Pilot Study of Local Anesthesia for Inguinal Hernia Surgery in Older Adults

University of Wisconsin, Madison

NCT04706026

RECRUITING Phase 4 70 participants

Erector Spinae Plane Block Catheters and Intrathecal Morphine for Hepatic Resection

University of California, San Diego

NCT04849455

RECRUITING NA 66 participants

Effects of Erector Spinae Plane Block on Postoperative Pain Following Lumbar Fusion Surgery

University of Massachusetts, Worcester

NCT06528288

RECRUITING NA 50 participants

Effect of Silver Diamine Fluoride on Local Anesthesia in Hypomineralized Molars

University of Michigan

NCT05964387

RECRUITING NA 40 participants

Obstetric Placement Study Using EST

Stanford University

NCT04109365

RECRUITING Phase 4 35 participants

Split Face Study of the Duration of Local Anesthetics - Fourth Arm

Weill Medical College of Cornell University

NCT06694714

ACTIVE NOT RECRUITING 230 participants

Local Anesthetic Response in Ehlers-Danlos Syndrome (EDS) and Healthy Volunteers

Vanderbilt University Medical Center

NCT04036305

ACTIVE NOT RECRUITING Phase 4 18 participants

Intralipid® 20% for Reversal of Local Anesthetics

Hospital for Special Surgery, New York

NCT03968822

COMPLETED Phase 4 150 participants

Study of OraVerse® for Safety and Efficacy in Pediatric Dental Patients

Novocol Pharmaceutical of Canada

NCT01474382

COMPLETED Phase 3 120 participants

A Study of the Safety and Anesthetic Effect of AG-920 Topical Ophthalmic Solution

American Genomics

NCT04829344

COMPLETED Phase 4 85 participants

Liposomal Bupivacaine Versus Bupivacaine for for Postoperative Pain Control in Shoulder Surgery

Bassett Healthcare

NCT04180943

COMPLETED Phase 3 61 participants

A Study of Safety and the Local Anesthetic Effect of AG-920 Ophthalmic Solution in a Pediatric Population

American Genomics

NCT05325853

COMPLETED Phase 1 40 participants

Cooling Anesthesia for Intravitreal Injection

Recens Medical

NCT03732287

COMPLETED Phase 4 36 participants

Trial of Injected Liposomal Bupivacaine vs Bupivacaine Infusion After Surgical Stabilization of Rib Fractures

Denver Health and Hospital Authority

NCT03305666

COMPLETED 29 participants

Changes in Tissue Oxygenation Following Regional Anesthesia

Nationwide Children's Hospital

NCT01418690

COMPLETED Phase 4 26 participants

Clinical Trial Comparing Effectiveness of Buffered Versus Unbuffered Local Anesthetic in Children Ages 10-12 Years

University of North Carolina, Chapel Hill

NCT03562481

COMPLETED Early Phase 1 21 participants

Preoperative Regional Nerve Block for Acute and Chronic Post-Operative Pain Following Mastectomy

University of Alabama at Birmingham

NCT04019834

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 3 2
Phase 4 7

Named interventions

Most-linked intervention names on Anesthesia, Local records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

AG-920 Drug
2 trials
interscalene nerve block Drug
1 trials
OraVerse Drug
1 trials
Bupivacaine indwelling catheter Drug
1 trials
Liposomal bupivacaine injection Drug
1 trials
Cooling Anesthesia Device
1 trials
Placebo regional nerveblock with normal saline Other
1 trials
regional nerve block with local anesthesia of bupivacaine with steroid Drug
1 trials

US sites by state

Facility locations filed on Anesthesia, Local trials. A trial with sites in several states counts in each.

California 5 trials
Texas 4 trials
New York 3 trials
Ohio 2 trials
Wisconsin 1 trials
Washington 1 trials
Utah 1 trials
Tennessee 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Anesthesia, Local page

19 registered trials, 8 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 8 Anesthesia, Local trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • American Genomics sponsors the most Anesthesia, Local trials on record, review their full trial history before evaluating a specific study. See American Genomics's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Anesthesia, Local condition card totals 19 registered trials; most-linked intervention AG-920; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.