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NCT05067088 · ClinicalTrials.gov registry record
Novel physIologiC prEdictors of Positive Airway Pressure Effectiveness
A clinical trial of Obstructive Sleep Apnea, sponsored by Yale University.
- Active
- Registry status
- 267
- Enrollment target
- 1
- Study location
NCT05067088: Active study of Obstructive Sleep Apnea, sponsored by Yale University.
NCT05067088 is a study of Obstructive Sleep Apnea that is active but no longer recruiting, run by Yale University. The registered enrollment target is 267 participants, above the 220-participant average among 155 other Obstructive Sleep Apnea trials with a reported enrollment target (21% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05067088, a study of Obstructive Sleep Apnea, is active but no longer recruiting, sponsored by Yale University.
- ACTIVE NOT RECRUITING
- Registry status
- 267 participants
- Enrollment target
- 1
- Study location
Study Summary
Millions of Americans suffer from high blood pressure, diabetes, strokes and motor vehicle accidents due to ineffective treatment of obstructive sleep apnea (OSA). Our preliminary data suggest that physiological causes of OSA such as easy arousability (low arousal threshold) or unstable breathing control (high loop gain) may influence effectiveness of OSA's most common treatment, continuous positive airway pressure (CPAP). The NICE-PAP study will examine how the physiologic traits that cause OSA in each individual impact CPAP effectiveness and can lead to personalized OSA treatments that improve patient lives.
Primary Outcome
average daily CPAP use (hours/night)
Conditions Studied
Interventions
- OTHER CPAP (all patients receive CPAP as part of routine clinical care)
Study Locations (1)
Connecticut
- Yale New Haven Hospital Sleep Center - North Haven
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 267 participants |
| Start Date | 2022-01-01 |
| Est. Completion | 2026-08-28 |
What the registry record for NCT05067088 still lists
NCT05067088 is an observational study that tracks outcomes without assigning an intervention. The registered 267 participants enrollment target is mid-sized for trials with a published cap, above the 220-participant average among 155 other Obstructive Sleep Apnea trials with a reported enrollment target (21% higher).
The record links to 1 condition, with Obstructive Sleep Apnea appearing as the primary indexed condition, and to 1 intervention - of which CPAP (all patients receive CPAP as part of routine clinical care) is the first listed.
NCT05067088 reports a single indexed study location in Connecticut.
Frequently Asked Questions
What is clinical trial NCT05067088 about?
NCT05067088 is a clinical study titled "Novel physIologiC prEdictors of Positive Airway Pressure Effectiveness". Millions of Americans suffer from high blood pressure, diabetes, strokes and motor vehicle accidents due to ineffective treatment of obstructive sleep apnea (OSA). Our preliminary data suggest that physiological causes of OSA such as easy arousability (low arousal threshold) or unstable breathing co...
What is the current status of trial NCT05067088?
This trial is currently active not recruiting. The enrollment target is 267 participants. The study started on 2022-01-01. Estimated completion is 2026-08-28.
What conditions does trial NCT05067088 study?
This clinical trial studies the following conditions: Obstructive Sleep Apnea.
What interventions are being tested in trial NCT05067088?
The interventions under investigation include: CPAP (all patients receive CPAP as part of routine clinical care) (OTHER).
Who is sponsoring clinical trial NCT05067088?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05067088 being conducted?
This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obstructive Sleep Apnea
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05067088's enrollment target sits among peer trials
267 26th of 155 higher than 130 of 155 other Obstructive Sleep Apnea trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obstructive Sleep Apnea trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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