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NCT03234530 · ClinicalTrials.gov registry record
World Trade Center Kidney-Link
A clinical trial of Obstructive Sleep Apnea and Chronic Kidney Diseases, sponsored by Icahn School of Medicine at Mount Sinai.
- Completed
- Registry status
- 555
- Enrollment target
- 1
- Study location
NCT03234530: Completed study of Obstructive Sleep Apnea and Chronic Kidney Diseases, sponsored by Icahn School of Medicine at Mount Sinai.
NCT03234530 is a study of Obstructive Sleep Apnea and Chronic Kidney Diseases that has completed, run by Icahn School of Medicine at Mount Sinai. The registered enrollment target is 555 participants, above the 218-participant average among 155 other Obstructive Sleep Apnea trials with a reported enrollment target (155% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03234530, a study of Obstructive Sleep Apnea and Chronic Kidney Diseases, has completed, sponsored by Icahn School of Medicine at Mount Sinai.
- COMPLETED
- Registry status
- 555 participants
- Enrollment target
- 1
- Study location
Study Summary
This study focuses on the prevalence and identification of kidney disease among participants of the WTC Health Program and the study team are planning to assess kidney disease in a multi-factorial manner. The first aim of this study is to correlate kidney dysfunction with 9/11 exposure, and the study team predicts that exposure to 9/11 is an independent risk factor in kidney disease among the WTC Health Program participants. Secondly, the study team proposes that a well-established WTC-related condition, obstructive sleep apnea (OSA), is independently associated with kidney disease. In addition, the study team believe there is a temporal causative relationship between evidence of kidney disease and the severity of OSA. Finally, the last aim is to further identify and explore potential mechanisms and phenotypes of kidney disease in participants of the WTC Health Programs. Regardless of whether the analyses support or reject these hypotheses, the findings will be of equally great public health importance. Successful completion of the proposed research would address a critical knowledge gap regarding the risk of kidney damage among this group of patients, and would inform future mechanistic studies with the potential to impact prevention.
Primary Outcome
eGFR will be calculated using the Chronic Kidney Disease Epidemiology Consortium (CKD-EPI) equations. The proposed studies will evaluate differences in the combined creatinine-cystatin C eGFR, which provides the most accurate estimate of GFR, and the creatinine-based CKD-EPI eGFR, which is more practical for use in clinical practice and in monitoring programs. Values \> 200 will be set to 200mL/min/1.73m2
Conditions Studied
Study Locations (1)
New York
- Icahn School of Medicine at Mount Sinai - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 555 participants |
| Start Date | 2017-11-01 |
| Est. Completion | 2021-06-01 |
What the finished NCT03234530 record still lists
NCT03234530 is an observational study that tracks outcomes without assigning an intervention. The registered 555 participants enrollment target is mid-sized for trials with a published cap, above the 218-participant average among 155 other Obstructive Sleep Apnea trials with a reported enrollment target (155% higher).
The record links to 2 conditions, with Obstructive Sleep Apnea appearing as the primary indexed condition, and to 0 interventions.
NCT03234530 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT03234530 about?
NCT03234530 is a clinical study titled "World Trade Center Kidney-Link". This study focuses on the prevalence and identification of kidney disease among participants of the WTC Health Program and the study team are planning to assess kidney disease in a multi-factorial manner. The first aim of this study is to correlate kidney dysfunction with 9/11 exposure, and the stud...
What is the current status of trial NCT03234530?
This trial is currently completed. The enrollment target is 555 participants. The study started on 2017-11-01. Estimated completion is 2021-06-01.
What conditions does trial NCT03234530 study?
This clinical trial studies the following conditions: Obstructive Sleep Apnea, Chronic Kidney Diseases.
Who is sponsoring clinical trial NCT03234530?
This trial is sponsored by Icahn School of Medicine at Mount Sinai, which has 708 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03234530 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT03234530's enrollment target sits among peer trials
555 13th of 155 higher than 143 of 155 other Obstructive Sleep Apnea trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obstructive Sleep Apnea trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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