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Obesity: early-phase trial registry
306 of 1,057 indexed Obesity trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #3 of 28,963 conditions by registered trial count.
1,057 US clinical trials · 306 currently recruiting · #3 of 28,963 conditions by registered trial count
Obesity: 1,057 US clinical trials tracked, 306 recruiting.
Obesity is the subject of 1,057 registered US clinical trials on ClinicalTrials.gov, 306 of them currently open to new participants. 107 are in Phase 3-4 (later-stage) and 196 in Phase 1-2 (earlier-stage). The most active sponsor is Eli Lilly and Company, running 48 of these trials.
Open enrollment, early-phase tilt
Obesity has 1,057 registered US clinical trials, 306 of them open to new participants right now, about 29% of the total.
- 306
- recruiting participants now
- 29%
- of trials open to enrollment
- 107
- in Phase 3-4 (later-stage)
- 48
- top sponsor: Eli Lilly and Company
Corpus placement: #3 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.
Key findings
What ClinicalTrials.gov does not surface for Obesity on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.
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Obesity is recruiting below its size-band peers.
306 of 1,057 indexed trials (28.9%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Obesity trials is spread across many organizations.
Eli Lilly and Company accounts for 48 of 1,057 trials (4.5%). 314 distinct sponsors appear on at least one study for this condition label.
-
Typical Obesity enrolment sits around 90 participants.
Median target enrolment is 90 among the 1,054 trials that report a genuine target (sentinel values excluded). 555 of those (52.7%) plan for fewer than 100 participants.
-
Obesity research is mostly interventional.
894 interventional and 163 observational studies make up this index (84.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
1,057 total, page 2 of 22
Fasting Insulin and HOMA-IR by Age, Sex, Race/Ethnicity, BMI, and PCOS Diagnosis
Lilli Health
NCT05950282
CARBON: UAB Cardiovascular Research Biobank
University of Alabama at Birmingham
NCT05067231
Adrenergic Cholinergic Enteric Measures/Mapping
University of Louisville
NCT04013282
SMARTer Weight Loss Management
Northwestern University
NCT05861973
A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight
Novo Nordisk A/S
NCT07253285
Eliminating Severe Maternal Morbidity With Heart Health Doulas Trial
University of Pittsburgh
NCT05655936
Digital InteGrated Behavioral TreatmeNt for Comorbid ObesITy and DeprEssion Among Racial and Ethnic Adults Age 50 and Older
University of Illinois at Chicago
NCT06636058
The Path to Optimal Black Maternal Heart Health: Comparing Two CVD Risk Reduction Interventions (Change of HEART)
Temple University
NCT05499507
Predicting Appendicular Lean and Fat Mass With Bioelectrical Impedance Analysis Among Adult Patients With Obesity.
University of Roma La Sapienza
NCT06545435
Immunoinflammatory Response in Post Cardiac Arrest Syndrome (PCAS)
MaineHealth
NCT02664831
A Bilingual Virtually-based Intervention (PEDALL) for the Prevention of Weight Gain in Childhood ALL Patients Considering Key Genetic and Sociodemographic Risk Factors
Columbia University
NCT05963971
Cognitive Strategies for Weight Loss
The Miriam Hospital
NCT05799846
Addressing Diabetes by Elevating Access to Nutrition
Stanford University
NCT05228860
Fit for Duty: mHealth Intervention for Weight Gain Prevention
University of North Carolina, Chapel Hill
NCT06110273
Mechanisms Underlying Individual Variations of Taste and Smell in Obesity
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NCT04714892
Food at Home Study
University of Minnesota
NCT06286514
Inflammation, Diabetes, Ethnicity and Obesity Cohort
University of California, San Francisco
NCT03022682
Black Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention
Ohio State University
NCT06055036
A Research Study on How Well Different Doses of the Medicine UBT251 Help People Living With Overweight or Obesity
Novo Nordisk A/S
NCT07395687
Synchronous vs Asynchronous Remotely Delivered Lifestyle Interventions
University of Connecticut
NCT06393725
Tailoring Mobile Health Technology to Reduce Obesity and Improve Cardiovascular Health in Resource-Limited Neighborhood Environments
National Heart, Lung, and Blood Institute (NHLBI)
NCT03288207
PreventT2 Together: Examining the Efficacy of Couple-based Lifestyle Intervention to Prevent Type 2 Diabetes
University of Utah
NCT06690788
HealthyTogether: RCT of a Dyadic Weight Management Intervention
VA Office of Research and Development
NCT06619041
Mother-Baby Study - Observational
University of Michigan
NCT06039878
Delta GREENS Food is Medicine Intervention
Tufts University
NCT06358859
A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)
Eli Lilly and Company
NCT06439277
RESET System Pivotal Trial (Rev F)
Morphic Medical
NCT04101669
Reducing Obesity Using Social Ties Program
Weill Medical College of Cornell University
NCT06335810
Time-restricted Eating Versus Daily Continuous Calorie Restriction on Body Weight and Colorectal Cancer Risk Markers
University of Illinois at Chicago
NCT05114798
A Study of Retatrutide (LY3437943) in Participants With Obesity or Overweight
Eli Lilly and Company
NCT07232719
Evaluating the Effectiveness of a Food is Medicine Community Health Worker Program for Pregnant Women
Christiana Care Health Services
NCT06180811
Weight Loss Through Mayo Clinic Diet
Mayo Clinic
NCT06862375
Study to Evaluate HM15275 in Obese or Overweight Subjects Without Diabetes Mellitus
Hanmi Pharmaceutical Company Limited
NCT07205900
Spinal Cord Injury Model Systems (SCIMS) - Education Module
University of Miami
NCT06003686
Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea on Positive Airway Pressure Therapy
Amgen
NCT07225686
Sisters of Heart (Hermanas de Corazón): A Community Health Worker Initiative for Improving Heart Health in Migrant Farmworker Women
Emory University
NCT07111026
Alzheimer"s Imaging Biomarkers in Obesity
Cyrus A Raji
NCT05077579
Using Tailored mHealth Strategies to Promote Weight Management Among Adolescent and Young Adult Cancer Survivors
UNC Lineberger Comprehensive Cancer Center
NCT06848491
Caloric Restriction and Activity to Reduce Chemoresistance in B-ALL
Etan Orgel
NCT05082519
Predictors of Behavioral Obesity Treatment Outcomes
Rush University Medical Center
NCT05326477
Phenotype-Tailored Lifestyle Intervention for Obesity: A Randomized Trial
Mayo Clinic
NCT06770049
A Study of LY3971297 in Healthy Participants
Eli Lilly and Company
NCT06148272
A Research Study on How Well Different Doses of the Medicine NNC0662-0419 Help People Living With Overweight or Obesity
Novo Nordisk A/S
NCT07184632
Strategies for Improving Remote-based Weight Loss (PATH Trial)
The Miriam Hospital
NCT06166225
Understanding and Addressing Risks of Low Socioeconomic Status and Diabetes for Heart Failure
Johns Hopkins University
NCT06364644
A Study to Investigate Why Overweight People Regain Weight After Losing Weight in a Behavioral Weight Loss Program
University of Pittsburgh
NCT05748158
A Study of LY4086940 in Healthy Participants and Participants With Overweight or Obesity, With or Without Type 2 Diabetes
Eli Lilly and Company
NCT06945419
Fundus Ablation Registry (Gastric Fundus Mucosal Ablation for Weight Loss)
True You Weight Loss
NCT06428617
Effects of Whole vs. Nonfat Milk Consumption on Body Composition in Children
Boston Children's Hospital
NCT05464186
GENESIS: Genotype Guided - Natriuretic Peptides - Cardiometabolic Health Study
University of Alabama at Birmingham
NCT05216042
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 95 |
| Phase 2 | 101 |
| Phase 3 | 69 |
| Phase 4 | 38 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
What is open for Obesity right now
306 recruiting of 1,057 indexed (29% open).
Phase mix: 107 late (III/IV) vs 196 early (I/II) (early-phase heavy).
Top sponsor: Eli Lilly and Company (48 trials), 9 others listed. 50 shown below, recruiting first. #3 of 28,963 conditions by registered trial count.
How open-enrollment share is computed
Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.
Frequently Asked Questions
How many clinical trials are there for Obesity?
PlainTrial tracks 1,057 US clinical trials for Obesity, of which 306 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Obesity?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.