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NCT04714892 · ClinicalTrials.gov registry record

Mechanisms Underlying Individual Variations of Taste and Smell in Obesity

A clinical trial of Obesity, sponsored by National Institute on Alcohol Abuse and Alcoholism (NIAAA).

Recruiting
Registry status
350
Enrollment target
1
Study location

NCT04714892: Recruiting study of Obesity, sponsored by National Institute on Alcohol Abuse and Alcoholism (NIAAA).

NCT04714892 is a study of Obesity that is actively recruiting participants, run by National Institute on Alcohol Abuse and Alcoholism (NIAAA). The registered enrollment target is 350 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (57% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04714892, a study of Obesity, is actively recruiting participants, sponsored by National Institute on Alcohol Abuse and Alcoholism (NIAAA).

RECRUITING
Registry status
350 participants
Enrollment target
1
Study location

Study Summary

Background: Changes to the sense of taste or smell can change eating behavior. This may contribute to obesity. Researchers want to see how taste and smell perceptions that affect food choices may differ between people with obesity and without obesity. Objective: To understand the role that senses of taste and smell play in food intake. Eligibility: Adults ages 18-65 with obesity and without obesity Design: Participants will be screened with a medical history and physical exam. They will have a neurological and sensory exam. They will give blood and urine samples. They will be checked for previous SARS-CoV-2 infection. They will complete questionnaires about their eating habits, alcohol use, and smoking history. Participants will have 2 study visits. Participants will give stool, urine, blood, hair, nasal, and saliva samples. These samples will be used for gene testing. Participants will have their weight, height, and hip and waist circumference measured. They will have an imaging scan that measures body composition. Participants will complete questionnaires about their health, eating habits, and food preferences. Participants will have taste tests and smell tests. They will have sensory tests to assess their response to stimuli. Participants will have a dietary assessment. They will complete a food diary and a diet history questionnaire. Participants will get a meal to eat. Data will be collected about their experience. Participants will complete a sleep diary and wear a watch to measure their activity....

Primary Outcome

Compare individuals with obesity to healthy controls in measures of taste and smell and eating behaviors.

Conditions Studied

Study Locations (1)

Maryland

  • National Institutes of Health Clinical Center - Bethesda

Trial Details

FieldValue
Enrollment Target 350 participants
Start Date 2022-05-11
Est. Completion 2026-12-31

What NCT04714892 shows while recruiting

NCT04714892 is an observational study that tracks outcomes without assigning an intervention. The registered 350 participants enrollment target is mid-sized for trials with a published cap, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (57% lower).

The record links to 1 condition, with Obesity appearing as the primary indexed condition, and to 0 interventions.

NCT04714892 reports a single indexed study location in Maryland.

Frequently Asked Questions

What is clinical trial NCT04714892 about?

NCT04714892 is a clinical study titled "Mechanisms Underlying Individual Variations of Taste and Smell in Obesity". Background: Changes to the sense of taste or smell can change eating behavior. This may contribute to obesity. Researchers want to see how taste and smell perceptions that affect food choices may differ between people with obesity and without obesity. Objective: To understand the role that senses...

What is the current status of trial NCT04714892?

This trial is currently recruiting. The enrollment target is 350 participants. The study started on 2022-05-11. Estimated completion is 2026-12-31.

What conditions does trial NCT04714892 study?

This clinical trial studies the following conditions: Obesity.

Who is sponsoring clinical trial NCT04714892?

This trial is sponsored by National Institute on Alcohol Abuse and Alcoholism (NIAAA), which has 93 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04714892 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Obesity

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04714892's enrollment target sits among peer trials

350 184th of 1053 higher than 866 of 1,053 other Obesity trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04714892, the US trial registry maintained by the National Library of Medicine. NCT04714892 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.