Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Obesity: early-phase trial registry
306 of 1,057 indexed Obesity trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #3 of 28,963 conditions by registered trial count.
1,057 US clinical trials · 306 currently recruiting · #3 of 28,963 conditions by registered trial count
Obesity: 1,057 US clinical trials tracked, 306 recruiting.
Obesity is the subject of 1,057 registered US clinical trials on ClinicalTrials.gov, 306 of them currently open to new participants. 107 are in Phase 3-4 (later-stage) and 196 in Phase 1-2 (earlier-stage). The most active sponsor is Eli Lilly and Company, running 48 of these trials.
Open enrollment, early-phase tilt
Obesity has 1,057 registered US clinical trials, 306 of them open to new participants right now, about 29% of the total.
- 306
- recruiting participants now
- 29%
- of trials open to enrollment
- 107
- in Phase 3-4 (later-stage)
- 48
- top sponsor: Eli Lilly and Company
Corpus placement: #3 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.
Key findings
What ClinicalTrials.gov does not surface for Obesity on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.
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Obesity is recruiting below its size-band peers.
306 of 1,057 indexed trials (28.9%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Obesity trials is spread across many organizations.
Eli Lilly and Company accounts for 48 of 1,057 trials (4.5%). 314 distinct sponsors appear on at least one study for this condition label.
-
Typical Obesity enrolment sits around 90 participants.
Median target enrolment is 90 among the 1,054 trials that report a genuine target (sentinel values excluded). 555 of those (52.7%) plan for fewer than 100 participants.
-
Obesity research is mostly interventional.
894 interventional and 163 observational studies make up this index (84.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
1,057 total, page 17 of 22
Effect of Conjugated Linoleic Acid Supplement on Body Composition
University of North Carolina
NCT00347373
Feelings About Exercise
The Miriam Hospital
NCT03598647
Cognitive Therapy for Binge-Eating Disorder
University of North Carolina, Chapel Hill
NCT00050037
Low Fat Vegan or American Heart Association Diets & Cardiovascular Risk in Obese 9-18 y.o. With Elevated Cholesterol
The Cleveland Clinic
NCT01817491
Assessment of Changes in Abdominal Fat
Indiana University
NCT00228579
Adipokines Effect in Myometrial Contractility
University of Minnesota
NCT03505541
Diet, Eating, and Lifestyle Improvement for Valued Employees and Their Relatives
University of Pennsylvania
NCT03277040
Characterization of Hyperparathyroidism and Vitamin D Deficiency in Obesity
Weill Medical College of Cornell University
NCT00288873
Modulation of Esophageal Inflammation in Barrett's Esophagus by Omega-3 Fatty Acids
Mayo Clinic
NCT01733147
Progressive Weight Loss and Metabolic Health
Washington University School of Medicine
NCT01299519
Insulin Resistance and Reward
VA Office of Research and Development
NCT02241603
Fruit and Vegetable Prescription Program
Beth Comerford
NCT04072757
Molecular Mechanisms of Exercise Benefits to Insulin Resistant People
Mayo Clinic
NCT04158375
Variability of Physical Assessments in an Older Population That is Overweight or Obese
Versanis Bio
NCT05174923
Effect of Resvida, a Comparison With Calorie Restriction Regimen
Washington University School of Medicine
NCT00823381
Improving Diabetes Outcomes Through Lifestyle Change (IDOLc)Study
Massachusetts General Hospital
NCT01665989
Biologic Effects of Dehydroepiandrosterone (DHEA) in Humans
National Institute on Aging (NIA)
NCT00099697
NT-proBNP Levels and Obesity in Pregnancy
Duke University
NCT04049136
The Childhood Health and Asthma Management Program
University of Florida
NCT02303561
A Multiple Health Behavior Change Intervention for Overweight and Obese Smokers
Brown University
NCT05136430
Clinical Outcomes, Nutritional Status, Exercise and Psychosocial Factors in Pediatric Hematopoietic Cell Transplant
University of Michigan Rogel Cancer Center
NCT02734797
Evaluation of Liver and Cardiometabolic Health Benefits on Low Carbohydrate Ketogenic Diet
Virginia Commonwealth University
NCT03141008
To Investigate the Safety, Tolerability and Pharmacodynamics of GSK2890457 in Healthy Volunteers and Subjects With Type 2 Diabetes
GlaxoSmithKline
NCT01725126
Varying the Energy Density and Portion Size of the Main Course After a First-course Salad
Penn State University
NCT01729390
The Effects of Yoga on Body Image in College Women
University of Delaware
NCT03262350
Apnea, Bariatric Surgery Versus Continuous Positive Airway Pressure (CPAP) Trial
University of Pittsburgh
NCT01187771
Study of Low Level Laser Therapy to Reduce Body Circumference in Obese Individuals
Erchonia Corporation
NCT01821352
Mindfulness Training to Promote Healthy Diet and Physical Activity in Teens
University of Massachusetts, Worcester
NCT01975896
Effects of Exercise Training Intensity on Fitness and Insulin Sensitivity in African Americans
East Carolina University
NCT02892331
Seasonal Patterns of Stress, Diet and Physical Activity - Life in All Seasons (LENAS)
USDA Grand Forks Human Nutrition Research Center
NCT01674296
Motivational Interviewing for Weight Loss With Young Adults
Virginia Commonwealth University
NCT01899625
Ghrelin Regulation and Structure: Effect of Diet Composition on Ghrelin
Oregon Health and Science University
NCT00694512
Diet, Imaging and Energy Balance Trial (DIET)
Duke University
NCT00787280
Effect of Vitamin D3 Supplementation on Insulin Resistance and Cardiovascular Risk Factors in Obese Adolescents
Mayo Clinic
NCT00858247
Effects of Pitavastatin on Insulin Sensitivity and Liver Fat
Massachusetts General Hospital
NCT02290106
Rheumatoid Arthritis Coping Enhancement
Duke University
NCT04246827
Vitamin E Pharmacokinetics and Biomarkers in Normal and Obese Women
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00862433
Randomized Trial Comparing Laparoscopic Roux-en-y Gastric Bypass to Micro-laparoscopic Roux-en-y Gastric Bypass
Suzanne J. Rose
NCT01183273
Gender- and Culturally-Sensitive Weight Loss Intervention for Hispanic Males
University of Arizona
NCT02783521
Effect of Obesity on Immune Response to Pneumovax 23
University of Florida
NCT02471014
Multiple Ascending Dose Study of AMG 598 in Adults With Obesity
Amgen
NCT03757130
Functional MRI of Stress in Obesity
Yale University
NCT01719484
MPOWERed Messages: Tailored Mobile Messages to Enhance Weight Loss for Teens
University of Michigan
NCT01448551
Pilot Behavioral Support Intervention After Bariatric Surgery
Geisinger Clinic
NCT03092479
A Multi-Center Study in Men With Acquired Hypogonadotropic Hypogonadism to Compare Changes in Body Composition and Metabolic Parameters With Diet and Exercise in Conjunction With Treatment With 12.5 mg or 25 mg Enclomiphene
Repros Therapeutics
NCT02651688
Exercise as a Buffer Against Stress-induced Overeating
The Miriam Hospital
NCT02936076
Oxidative Stress in Asthma
Bastiaan Driehuys
NCT04512547
Bariatric Surgery and Weight Loss on Energy Metabolism and Insulin Sensitivity
Pennington Biomedical Research Center
NCT00936130
Regulation of Muscle Protein Phenotype in Humans With Obesity
Mayo Clinic
NCT04700800
Eating Mindfully to Prevent Weight Regain
University of Utah
NCT04847843
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 95 |
| Phase 2 | 101 |
| Phase 3 | 69 |
| Phase 4 | 38 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
What is open for Obesity right now
306 recruiting of 1,057 indexed (29% open).
Phase mix: 107 late (III/IV) vs 196 early (I/II) (early-phase heavy).
Top sponsor: Eli Lilly and Company (48 trials), 9 others listed. 50 shown below, recruiting first. #3 of 28,963 conditions by registered trial count.
How open-enrollment share is computed
Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.
Frequently Asked Questions
How many clinical trials are there for Obesity?
PlainTrial tracks 1,057 US clinical trials for Obesity, of which 306 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Obesity?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.