Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Obesity: early-phase trial registry
306 of 1,057 indexed Obesity trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #3 of 28,707 conditions by registered trial count.
1,057 US clinical trials · 306 currently recruiting · #3 of 28,707 conditions by registered trial count
Obesity: 1,057 US clinical trials tracked, 306 recruiting.
Obesity is the subject of 1,057 registered US clinical trials on ClinicalTrials.gov, 306 of them currently open to new participants. 107 are in Phase 3-4 (later-stage) and 196 in Phase 1-2 (earlier-stage). The most active sponsor is Eli Lilly and Company, running 48 of these trials.
Enrollment posture brief
Registry condition obesity
OPEN 306 | RECR 29% | LATE 107 | EARLY 196 | RANK #3 | SPON 48
Volume-matched condition peers
Nearest open-share peer: Metastatic Pancreatic Adenocarcinoma (29% recruiting · 38 trials)
Obesity lists 306 open slots (29% of 1,057 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Obesity on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Obesity is recruiting below its size-band peers.
306 of 1,057 indexed trials (28.9%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Obesity trials is spread across many organizations.
Eli Lilly and Company accounts for 48 of 1,057 trials (4.5%). 314 distinct sponsors appear on at least one study for this condition label.
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Typical Obesity enrolment sits around 90 participants.
Median target enrolment is 90 among the 1,054 trials that report a genuine target (sentinel values excluded). 555 of those (52.7%) plan for fewer than 100 participants.
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Obesity research is mostly interventional.
894 interventional and 163 observational studies make up this index (84.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
1,057 total, page 16 of 22
A Phase 1 Study to Assess HM15275 in Healthy and Obese Subjects.
Hanmi Pharmaceutical Company Limited
NCT06481098
Physical Fitness and Nutrition Intake in Bariatric Surgery Population
Geisinger Clinic
NCT02070354
A Trial of Tadalafil and Glycemic Traits
Thomas J. Wang, MD
NCT01444651
The Effect of Obesity on Oral Peri-implant Health - A Cross-Sectional Study
University of Iowa
NCT01878071
ESSENTIAL Trial™ Sham Cross-over
USGI Medical
NCT02279420
Improving Mental Health in Youth and Lowering Risk for Obesity Through a Digital Preventative Product
Ksana Health
NCT05638516
Exploring Optimal Treatment Components for Contactless Online Group-based Behavioral Weight Loss Program
University of South Carolina
NCT04514900
A Research Study Investigating Safety and Concentration in the Blood After One Dose Tablet of the New Medicine Monlunabant in Healthy Weight Japanese and Caucasian Men
Novo Nordisk A/S
NCT06542536
The Impact of Low-fat and Full-fat Dairy Consumption on Glucose Homeostasis (DAIRY Study)
Fred Hutchinson Cancer Center
NCT02663544
Resistance Exercise Effects on Fear Avoidance and Physical Function in Obese Older Adults With Low Back Pain
University of Florida
NCT01250262
Feasibility of a Partnered Approach to Prevent Diabetes
Northwestern University
NCT00302055
Effect of Soy Protein and Colorado Diet on Weight Loss and Maintenance
DuPont Nutrition and Health
NCT02380963
Promoting Child Inhibitory Control Skills Around Food
University of California, San Diego
NCT02077387
Adding Liraglutide to High Dose Insulin: Breaking the Cycle
Ildiko Lingvay
NCT01505673
Using Grassroots Wellness Coaching to Enhance Reach and Sustainability of Behavioral Weight Management
Virginia Commonwealth University
NCT05544708
The Family Grocery Pilot: Optimal Defaults in Online Grocery Shopping Among Families
State University of New York at Buffalo
NCT05899634
Food as Medicine: A Quasi-Randomized Control Trial of Healthy Foods for Chronic Disease Management
Cleveland Clinic Akron General
NCT05174078
Remote Delivery of Weight Management by Phone and Social Media
University of Kansas Medical Center
NCT02496871
Fat Tissue Microperfusion to Measure Leptin Secretion and Its Relations With Fat Breakdown in Humans
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NCT00001722
Using Mental Imagination to Prevent Excessive Gestational Weight Gain in Overweight and Obese Pregnant Women
Ohio State University
NCT04623008
Stress, Dietary Lapse and Weight Loss Among Adults With Type 2 Diabetes
Johns Hopkins Bloomberg School of Public Health
NCT00831194
The Effects of Exercise on Appetite Regulation in Overweight/Obese Individuals
University of Colorado, Denver
NCT02047721
Food Reward in Native American Women
University of Minnesota
NCT01623440
Holding vs. Continuing Incretin-based Therapies Before Upper Endoscopy
The Cleveland Clinic
NCT06533527
Effects of the GOLO Weight Management Program With and Without Release Supplement on Weight and Metabolic Parameters in Subjects With Obesity
Golo
NCT03842501
Behavioral and Pharmacologic Treatment of Binge Eating and Obesity: Maintenance Therapy
Yale University
NCT03047005
Study of Serum Markers for Cardiovascular Risk in Obese Youth and Impact of Lifestyle and Medication Intervention
Nemours Children's Clinic
NCT00139477
Increasing Uptake of Behavioral Weight Loss Programs Among Primary Care Patients
University of Florida
NCT02708121
Healthy4Baby: Preventing Postpartum Weight Retention Among Low-Income, Black Women
Temple University
NCT01530776
Development of a Mind Body Program for Obese Knee Osteoarthritis Patients With Comorbid Depression
University of Kentucky
NCT04334278
Effects of Red Light LED Therapy on Body Contouring
Vevazz
NCT03242564
Response Inhibition to High Calorie Food Cues Among Adolescents Following Active and Sedentary Video Game Play
Brigham Young University
NCT03407352
Remote Information Counseling for Elders
Indiana University
NCT01203995
A Study to Test How Well Different Doses of BI 3006337 Are Tolerated by People With Overweight or Obesity and With Fatty Liver Disease
Boehringer Ingelheim
NCT05970640
Mobile Weight Loss Intervention for Adolescent and Young Adult Cancer Survivors
UNC Lineberger Comprehensive Cancer Center
NCT06171945
Improving Diabetes After Bariatric Surgery
University of Pittsburgh
NCT00676923
Comparison Between Pyloric Preserving and Non-Pyloric Preserving Bariatric Surgery With Glucose Challenge
Medtronic - MITG
NCT00998374
Skeletal Muscle Diacylglycerol and Sphingolipids - Impact of Localization and Species on Insulin Resistance in Humans
University of Colorado, Denver
NCT03077360
Reproductive Hormonal Alterations in Obesity
University of Colorado, Denver
NCT01457703
Reducing Energy Density by Different Methods to Decrease Energy Intake
Penn State University
NCT01470300
A System for Preference Assessment in Mental Health
University of California, Los Angeles
NCT02183844
Fast Food Study: Assessment of the Effects of Fast-Food on Inflammatory Markers
National Institute on Aging (NIA)
NCT00233311
Craving, Binge Eating and Obesity
Yale University
NCT00414167
Increasing the Variety of Vegetables and Fruits Served to Preschool Children at a Snack
Penn State University
NCT01557218
Web-Based Weight Management for Individuals With Mental Illness
University of California, Los Angeles
NCT01324973
Brief Behavioral Weight Loss Treatment vs. Weight Watchers
The Miriam Hospital
NCT00249340
Approaches for Improving Long-term Weight Loss
The Miriam Hospital
NCT03799289
Micro-stream Capnography in Non-intubated Lean and Obese Patients With and Without Obstructive Sleep Apnea
The Cleveland Clinic
NCT00653471
OA Clinic-Community CARE Model
University of North Carolina, Chapel Hill
NCT05349500
EHR Embedded Comparative Effectiveness Studies--WWC
Dartmouth-Hitchcock Medical Center
NCT04514679
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 95 |
| Phase 2 | 101 |
| Phase 3 | 69 |
| Phase 4 | 38 |
Top Sponsors
Named interventions
Most-linked intervention names on Obesity records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Obesity trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Obesity page
1,057 registered trials, 306 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 306 Obesity trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Eli Lilly and Company sponsors the most Obesity trials on record, review their full trial history before evaluating a specific study. See Eli Lilly and Company's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Obesity condition card totals 1,057 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.