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ClinicalTrials.gov 306 recruiting now early-phase tilt #3 of 28,963 conditions

Obesity: early-phase trial registry

306 of 1,057 indexed Obesity trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #3 of 28,963 conditions by registered trial count.

1,057 US clinical trials · 306 currently recruiting · #3 of 28,963 conditions by registered trial count

Obesity: 1,057 US clinical trials tracked, 306 recruiting.

Obesity is the subject of 1,057 registered US clinical trials on ClinicalTrials.gov, 306 of them currently open to new participants. 107 are in Phase 3-4 (later-stage) and 196 in Phase 1-2 (earlier-stage). The most active sponsor is Eli Lilly and Company, running 48 of these trials.

Open enrollment, early-phase tilt

Obesity has 1,057 registered US clinical trials, 306 of them open to new participants right now, about 29% of the total.

306
recruiting participants now
29%
of trials open to enrollment
107
in Phase 3-4 (later-stage)
48
top sponsor: Eli Lilly and Company

Corpus placement: #3 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.

Key findings

What ClinicalTrials.gov does not surface for Obesity on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.

  1. Obesity is recruiting below its size-band peers.

    306 of 1,057 indexed trials (28.9%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Obesity trials is spread across many organizations.

    Eli Lilly and Company accounts for 48 of 1,057 trials (4.5%). 314 distinct sponsors appear on at least one study for this condition label.

  3. Typical Obesity enrolment sits around 90 participants.

    Median target enrolment is 90 among the 1,054 trials that report a genuine target (sentinel values excluded). 555 of those (52.7%) plan for fewer than 100 participants.

  4. Obesity research is mostly interventional.

    894 interventional and 163 observational studies make up this index (84.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 195Phase 2101Phase 369Phase 438

Open and recent trials

1,057 total, page 16 of 22

COMPLETED Phase 1 74 participants

A Phase 1 Study to Assess HM15275 in Healthy and Obese Subjects.

Hanmi Pharmaceutical Company Limited

NCT06481098

COMPLETED 73 participants

Physical Fitness and Nutrition Intake in Bariatric Surgery Population

Geisinger Clinic

NCT02070354

COMPLETED Phase 3 73 participants

A Trial of Tadalafil and Glycemic Traits

Thomas J. Wang, MD

NCT01444651

COMPLETED 73 participants

The Effect of Obesity on Oral Peri-implant Health - A Cross-Sectional Study

University of Iowa

NCT01878071

COMPLETED NA 73 participants

ESSENTIAL Trial™ Sham Cross-over

USGI Medical

NCT02279420

COMPLETED NA 73 participants

Improving Mental Health in Youth and Lowering Risk for Obesity Through a Digital Preventative Product

Ksana Health

NCT05638516

COMPLETED NA 73 participants

Exploring Optimal Treatment Components for Contactless Online Group-based Behavioral Weight Loss Program

University of South Carolina

NCT04514900

COMPLETED Phase 1 73 participants

A Research Study Investigating Safety and Concentration in the Blood After One Dose Tablet of the New Medicine Monlunabant in Healthy Weight Japanese and Caucasian Men

Novo Nordisk A/S

NCT06542536

COMPLETED NA 72 participants

The Impact of Low-fat and Full-fat Dairy Consumption on Glucose Homeostasis (DAIRY Study)

Fred Hutchinson Cancer Center

NCT02663544

COMPLETED NA 72 participants

Resistance Exercise Effects on Fear Avoidance and Physical Function in Obese Older Adults With Low Back Pain

University of Florida

NCT01250262

COMPLETED NA 72 participants

Feasibility of a Partnered Approach to Prevent Diabetes

Northwestern University

NCT00302055

COMPLETED NA 72 participants

Effect of Soy Protein and Colorado Diet on Weight Loss and Maintenance

DuPont Nutrition and Health

NCT02380963

COMPLETED NA 72 participants

Promoting Child Inhibitory Control Skills Around Food

University of California, San Diego

NCT02077387

COMPLETED Phase 4 71 participants

Adding Liraglutide to High Dose Insulin: Breaking the Cycle

Ildiko Lingvay

NCT01505673

COMPLETED NA 71 participants

Using Grassroots Wellness Coaching to Enhance Reach and Sustainability of Behavioral Weight Management

Virginia Commonwealth University

NCT05544708

COMPLETED NA 70 participants

The Family Grocery Pilot: Optimal Defaults in Online Grocery Shopping Among Families

State University of New York at Buffalo

NCT05899634

COMPLETED NA 70 participants

Food as Medicine: A Quasi-Randomized Control Trial of Healthy Foods for Chronic Disease Management

Cleveland Clinic Akron General

NCT05174078

COMPLETED NA 70 participants

Remote Delivery of Weight Management by Phone and Social Media

University of Kansas Medical Center

NCT02496871

COMPLETED 70 participants

Fat Tissue Microperfusion to Measure Leptin Secretion and Its Relations With Fat Breakdown in Humans

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NCT00001722

COMPLETED NA 70 participants

Using Mental Imagination to Prevent Excessive Gestational Weight Gain in Overweight and Obese Pregnant Women

Ohio State University

NCT04623008

COMPLETED NA 70 participants

Stress, Dietary Lapse and Weight Loss Among Adults With Type 2 Diabetes

Johns Hopkins Bloomberg School of Public Health

NCT00831194

COMPLETED NA 69 participants

The Effects of Exercise on Appetite Regulation in Overweight/Obese Individuals

University of Colorado, Denver

NCT02047721

COMPLETED 69 participants

Food Reward in Native American Women

University of Minnesota

NCT01623440

COMPLETED Phase 4 69 participants

Holding vs. Continuing Incretin-based Therapies Before Upper Endoscopy

The Cleveland Clinic

NCT06533527

COMPLETED Phase 3 68 participants

Effects of the GOLO Weight Management Program With and Without Release Supplement on Weight and Metabolic Parameters in Subjects With Obesity

Golo

NCT03842501

COMPLETED Phase 2 68 participants

Behavioral and Pharmacologic Treatment of Binge Eating and Obesity: Maintenance Therapy

Yale University

NCT03047005

COMPLETED NA 66 participants

Study of Serum Markers for Cardiovascular Risk in Obese Youth and Impact of Lifestyle and Medication Intervention

Nemours Children's Clinic

NCT00139477

COMPLETED NA 66 participants

Increasing Uptake of Behavioral Weight Loss Programs Among Primary Care Patients

University of Florida

NCT02708121

COMPLETED Phase 2 66 participants

Healthy4Baby: Preventing Postpartum Weight Retention Among Low-Income, Black Women

Temple University

NCT01530776

COMPLETED NA 66 participants

Development of a Mind Body Program for Obese Knee Osteoarthritis Patients With Comorbid Depression

University of Kentucky

NCT04334278

COMPLETED NA 66 participants

Effects of Red Light LED Therapy on Body Contouring

Vevazz

NCT03242564

COMPLETED NA 65 participants

Response Inhibition to High Calorie Food Cues Among Adolescents Following Active and Sedentary Video Game Play

Brigham Young University

NCT03407352

COMPLETED NA 64 participants

Remote Information Counseling for Elders

Indiana University

NCT01203995

COMPLETED Phase 1 64 participants

A Study to Test How Well Different Doses of BI 3006337 Are Tolerated by People With Overweight or Obesity and With Fatty Liver Disease

Boehringer Ingelheim

NCT05970640

COMPLETED NA 63 participants

Mobile Weight Loss Intervention for Adolescent and Young Adult Cancer Survivors

UNC Lineberger Comprehensive Cancer Center

NCT06171945

COMPLETED 63 participants

Improving Diabetes After Bariatric Surgery

University of Pittsburgh

NCT00676923

COMPLETED 62 participants

Comparison Between Pyloric Preserving and Non-Pyloric Preserving Bariatric Surgery With Glucose Challenge

Medtronic - MITG

NCT00998374

COMPLETED NA 62 participants

Skeletal Muscle Diacylglycerol and Sphingolipids - Impact of Localization and Species on Insulin Resistance in Humans

University of Colorado, Denver

NCT03077360

COMPLETED NA 62 participants

Reproductive Hormonal Alterations in Obesity

University of Colorado, Denver

NCT01457703

COMPLETED NA 62 participants

Reducing Energy Density by Different Methods to Decrease Energy Intake

Penn State University

NCT01470300

COMPLETED NA 61 participants

A System for Preference Assessment in Mental Health

University of California, Los Angeles

NCT02183844

COMPLETED 61 participants

Fast Food Study: Assessment of the Effects of Fast-Food on Inflammatory Markers

National Institute on Aging (NIA)

NCT00233311

COMPLETED Phase 2 61 participants

Craving, Binge Eating and Obesity

Yale University

NCT00414167

COMPLETED NA 61 participants

Increasing the Variety of Vegetables and Fruits Served to Preschool Children at a Snack

Penn State University

NCT01557218

COMPLETED NA 60 participants

Web-Based Weight Management for Individuals With Mental Illness

University of California, Los Angeles

NCT01324973

COMPLETED NA 60 participants

Brief Behavioral Weight Loss Treatment vs. Weight Watchers

The Miriam Hospital

NCT00249340

COMPLETED NA 60 participants

Approaches for Improving Long-term Weight Loss

The Miriam Hospital

NCT03799289

COMPLETED Early Phase 1 60 participants

Micro-stream Capnography in Non-intubated Lean and Obese Patients With and Without Obstructive Sleep Apnea

The Cleveland Clinic

NCT00653471

COMPLETED NA 60 participants

OA Clinic-Community CARE Model

University of North Carolina, Chapel Hill

NCT05349500

COMPLETED NA 60 participants

EHR Embedded Comparative Effectiveness Studies--WWC

Dartmouth-Hitchcock Medical Center

NCT04514679

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Phase Distribution

PhaseTrial count
Phase 1 95
Phase 2 101
Phase 3 69
Phase 4 38

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What is open for Obesity right now

306 recruiting of 1,057 indexed (29% open).

Phase mix: 107 late (III/IV) vs 196 early (I/II) (early-phase heavy).

Top sponsor: Eli Lilly and Company (48 trials), 9 others listed. 50 shown below, recruiting first. #3 of 28,963 conditions by registered trial count.

How open-enrollment share is computed

Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.

Frequently Asked Questions

How many clinical trials are there for Obesity?

PlainTrial tracks 1,057 US clinical trials for Obesity, of which 306 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Obesity?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.