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NCT04700800 · ClinicalTrials.gov registry record · NA
Regulation of Muscle Protein Phenotype in Humans With Obesity
A NA study of Obesity, sponsored by Mayo Clinic.
- Completed
- Registry status
- NA
- Development phase
- 48
- Enrollment target
- 1
- Study location
NCT04700800 is a NA study of Obesity that has completed, run by Mayo Clinic. The registered enrollment target is 48 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state.
The verdict
NCT04700800, a NA study of Obesity, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- NA
- Development phase
- 48 participants
- Enrollment target
- 1
- Study location
Study Summary
A hallmark of muscle changes in obesity is an altered muscle fiber type profile, characterized by a reduced proportion of Type I fibers - a shift associated with adverse obesity-related health outcomes. This alteration can be linked to changes in the expression of myosin heavy chain (MHC) protein isoforms in the skeletal muscle of individuals with obesity. The investigators aim to modulate the metabolism of muscle MHC isoforms to uncover the biological mechanisms underlying this disrupted expression pattern in muscle of humans with obesity.
Conditions Studied
Interventions
- OTHER Exercise
Study Locations (1)
Arizona
- Mayo Clinic in Arizona - Scottsdale
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2021-10-07 |
| Est. Completion | 2024-10-02 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04700800
The ClinicalTrials.gov registry entry for NCT04700800 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 48 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (94% lower). The listed sponsor is Mayo Clinic, which has 2,844 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Obesity appearing as the primary indexed condition, and to 1 intervention - of which Exercise is the first listed.
NCT04700800 reports 1 study location spanning 1 distinct geographic area - top geographies include Arizona.
Frequently Asked Questions
What is clinical trial NCT04700800 about?
NCT04700800 is a clinical study titled "Regulation of Muscle Protein Phenotype in Humans With Obesity". A hallmark of muscle changes in obesity is an altered muscle fiber type profile, characterized by a reduced proportion of Type I fibers - a shift associated with adverse obesity-related health outcomes. This alteration can be linked to changes in the expression of myosin heavy chain (MHC) protein is...
What is the current status of trial NCT04700800?
This trial is currently completed. It is a NA study. The enrollment target is 48 participants. The study started on 2021-10-07. Estimated completion is 2024-10-02.
What conditions does trial NCT04700800 study?
This clinical trial studies the following conditions: Obesity.
What interventions are being tested in trial NCT04700800?
The interventions under investigation include: Exercise (OTHER).
Who is sponsoring clinical trial NCT04700800?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04700800 being conducted?
This trial has 1 study location across Arizona. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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