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ClinicalTrials.gov 58 recruiting now official registry

Non-Hodgkin Lymphoma clinical trials

58 of 105 indexed Non-Hodgkin Lymphoma trials are currently recruiting.

105 US clinical trials · 58 currently recruiting

Non-Hodgkin Lymphoma is the subject of 105 registered US clinical trials on ClinicalTrials.gov, 58 of them currently open to new participants. 6 are in Phase 3-4 (later-stage) and 85 in Phase 1-2 (earlier-stage). The most active sponsor is Baylor College of Medicine, running 7 of these trials.

The research picture

Non-Hodgkin Lymphoma has 105 registered US clinical trials, 58 of them open to new participants right now, about 55% of the total.

58
recruiting participants now
55%
of trials open to enrollment
6
in Phase 3–4 (later-stage)
7
top sponsor: Baylor College of Medicine
Phase 166Phase 219Phase 34Phase 42

Active & Recent Trials

105 total, page 1 of 3

RECRUITING 2,000 participants

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

Wake Forest University Health Sciences

NCT06418204

RECRUITING 2,000 participants

Evaluating the Impact of Social and Genetic Factors on Outcomes in Adolescent and Young Adult Cancer Survivors

ECOG-ACRIN Cancer Research Group

NCT06002828

RECRUITING Phase 4 787 participants

A Master Protocol to Evaluate the Long-Term Safety of (LY3527727) Pirtobrutinib

Eli Lilly and Company

NCT06876649

RECRUITING Phase 1 614 participants

A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies

BeOne Medicines

NCT05006716

RECRUITING Phase 2 496 participants

A Study to Evaluate Adverse Events and Change in Disease Activity of Subcutaneous (SC) Epcoritamab in Combination With Oral and Intravenous Anti-Neoplastic Agents in Adult Participants With Non-Hodgkin Lymphoma

Genmab

NCT05283720

RECRUITING Phase 3 400 participants

A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy

Lyell Immunopharma

NCT07188558

RECRUITING Phase 3 386 participants

A Study to Evaluate Efficacy, Safety, and PK of XEMBIFY®+Standard Medical Treatment (SMT) Compared to Placebo+SMT to Prevent Infections in Participants With HGG and Recurrent or Severe Infections Associated With B-cell Chronic Lymphocytic Leukemia, Multiple Myeloma, and Non-Hodgkin Lymphoma

Grifols Therapeutics

NCT05645107

RECRUITING 300 participants

Pre-malignant States to Hematologic Malignancies in Firefighters

Wake Forest University Health Sciences

NCT06870760

RECRUITING Phase 4 279 participants

A Study of (LY3527727) Pirtobrutinib in Participants With Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma or Non-Hodgkin Lymphoma

Eli Lilly and Company

NCT06876662

RECRUITING Phase 1 270 participants

Study of LYL314 in Aggressive Large B-Cell Lymphoma

Lyell Immunopharma

NCT05826535

RECRUITING Phase 1 250 participants

Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies

CellCentric

NCT04068597

RECRUITING Phase 2 216 participants

CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors for the Prevention of CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplant

City of Hope Medical Center

NCT06059391

RECRUITING Phase 1 184 participants

Phase1/2 Study of IPH6501 in Patients With Relapsed /Refractory B-Cell Non-Hodgkin Lymphoma

Innate Pharma

NCT06088654

RECRUITING Phase 1 155 participants

Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (ViPOR) in Relapsed/Refractory B-cell Lymphoma

National Cancer Institute (NCI)

NCT03223610

RECRUITING Phase 2 150 participants

Auto Stem Cell Transplant for Lymphoma Patients

Masonic Cancer Center, University of Minnesota

NCT03125642

RECRUITING 150 participants

Lentiviral Gene Therapy (Zamtocabtagene Autoleucel) LTFU

Miltenyi Biomedicine

NCT06116110

RECRUITING NA 140 participants

Lifestyle Intervention of Food and Exercise for Lymphoma Survivors

University of Miami

NCT05839210

RECRUITING Phase 1 135 participants

Dose-escalation and Dose-expansion Study of Safety of Azer-cel (PBCAR0191) in Participants With Relapsed/Refractory (r/r) Non-Hodgkin Lymphoma (NHL) and r/r B-cell Acute Lymphoblastic Leukemia (B-ALL)

Imugene Limited

NCT03666000

RECRUITING Phase 1 121 participants

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab or Glofitamab in Combination With CC-220 and/or CC-99282 in Participants With B-Cell Non-Hodgkin Lymphoma

Hoffmann-La Roche

NCT05169515

RECRUITING Phase 1 120 participants

A Safety and Efficacy Study Evaluating CTX112 in Subjects With Relapsed or Refractory B-Cell Malignancies

CRISPR Therapeutics

NCT05643742

RECRUITING Phase 1 120 participants

AS-1763 in Patients With Previously Treated CLL/SLL or Non-Hodgkin Lymphoma

Carna Biosciences

NCT05602363

RECRUITING NA 110 participants

Improving Exercise Capacity With a Tailored Physical Activity Intervention

Wake Forest University Health Sciences

NCT05595577

RECRUITING Phase 2 100 participants

Mozobil for Autologous Hematopoietic Stem Cell Transplantation

Thomas Jefferson University

NCT07188090

RECRUITING Phase 1 100 participants

Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

Newave Pharmaceutical

NCT04771572

RECRUITING Phase 1 98 participants

Study of SGR-1505 in Mature B-Cell Neoplasms

Schrödinger

NCT05544019

RECRUITING Phase 1 90 participants

Constitutive IL7R (C7R) Modified Banked Allogeneic CD30.CAR EBVSTS for CD30-Positive Lymphomas

Baylor College of Medicine

NCT06176690

RECRUITING Phase 2 80 participants

Chemoradiotherapy With Targeted Immunotherapy in Pediatric Lymphoma

New York Medical College

NCT05253495

RECRUITING Phase 1 79 participants

Safety and Preliminary Efficacy of MT-601 in Patients With Relapsed/Refractory Lymphoma

Marker Therapeutics

NCT05798897

RECRUITING Phase 1 72 participants

CRISPR-Edited Allogeneic Anti-CD19 CAR-T Cell Therapy for Relapsed/Refractory B Cell Non-Hodgkin Lymphoma (ANTLER)

Caribou Biosciences

NCT04637763

RECRUITING Phase 1 68 participants

Preliminary Safety and Tolerability of CD19x22 CAR T Cells in Adolescent and Adult R/R B-NHL Patients

University of Colorado, Denver

NCT05098613

RECRUITING Phase 1 64 participants

Activated T-Cells Expressing 2nd or 3rd Generation CD19-Specific CAR, Advanced B-Cell NHL, ALL, and CLL (SAGAN)

Baylor College of Medicine

NCT01853631

RECRUITING Phase 1 60 participants

CD30 CAR T Cells, Relapsed CD30 Expressing Lymphoma (RELY-30)

Baylor College of Medicine

NCT02917083

RECRUITING Phase 1 55 participants

Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid in Combination With Polatuzumab (ViPOR-P) in Relapsed/Refractory B-cell Lymphoma

National Cancer Institute (NCI)

NCT04739813

RECRUITING Phase 2 54 participants

Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Diseases

Fred Hutchinson Cancer Center

NCT06013423

RECRUITING Phase 2 53 participants

Amping up With PemJAK

Seda S. Tolu

NCT07283822

RECRUITING 50 participants

Transgene Assay Testing Service of Tumor Samples From Patients Who Received a Bristol-Myers Squibb Manufactured Gene Modified Cell Therapy and Have a Qualifying Second Primary Malignancy

Bristol-Myers Squibb

NCT06357754

RECRUITING Phase 2 49 participants

A Study of Carmustine With and Without Ethanol in Subjects With Lymphoma

VIVUS

NCT06915246

RECRUITING Phase 1 48 participants

SB-4826 in Adult Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin Lymphomas

University of California, San Diego

NCT07222631

RECRUITING Phase 2 45 participants

Epco, Zanu, Ritux for R/R FL or MZL

Reid Merryman, MD

NCT06563596

RECRUITING Phase 1 42 participants

ACE1831 in Adult Subjects With Relapsed/ Refractory CD20-expressing B-cell Malignancies

Acepodia Biotech

NCT05653271

RECRUITING Phase 2 39 participants

Isatuximab During Stem Cell Collection and Transplant in Patients With Multiple Myeloma and Lymphoma

Divaya Bhutani

NCT05346809

RECRUITING Phase 1 36 participants

Anti-CD19 Chimeric Antigen Receptor T Cells for Treatment of Relapsed or Refractory Non-Hodgkin Lymphoma

C. Babis Andreadis

NCT04545762

RECRUITING Phase 1 32 participants

PET Imaging Study of 64Cu-GRIP B for Patients Receiving CD19-directed CAR-T Therapy

Michael Randall

NCT06522932

RECRUITING Early Phase 1 30 participants

In-Human CXCR4 Imaging of Hematologic and Solid Tumors Using [68Ga]-Pentixafor-PET

Memorial Sloan Kettering Cancer Center

NCT05093335

RECRUITING Phase 2 30 participants

Phase II Study of Pirtobrutinib With Venetoclax In Relapsed-Refractory MCL (Mantle Cell Lymphoma) Patients

M.D. Anderson Cancer Center

NCT05529069

RECRUITING Phase 1 30 participants

Study of IOMAB-ACT Followed by CAR-T Cell Therapy for Patients Relapsed or Refractory (Diffuse Large B-cell Lymphoma

University of Texas Southwestern Medical Center

NCT06768905

RECRUITING Phase 2 25 participants

Obinutuzumab and ICE Chemotherapy in Refractory/Recurrent CD20+ Mature NHL

New York Medical College

NCT02393157

RECRUITING Phase 1 25 participants

Pomalidomide and Dose-Adjusted EPOCH +/- Rituximab for HIV-Associated Lymphomas

National Cancer Institute (NCI)

NCT05389423

RECRUITING Phase 1 24 participants

CD79b-19 CAR T Cells in Non-Hodgkin Lymphoma

Marcela V. Maus, M.D.,Ph.D.

NCT06026319

RECRUITING Phase 1 24 participants

TmCD19-IL18 in CD19+ Cancers

University of Pennsylvania

NCT05989204

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Phase Distribution

PhaseTrial count
Phase 1 66
Phase 2 19
Phase 3 4
Phase 4 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Non-Hodgkin Lymphoma Trial Landscape

105 indexed Non-Hodgkin Lymphoma studies · 58 recruiting (55%).

Phase mix: 6 late (III/IV) vs 85 early (I/II).

Top sponsor: Baylor College of Medicine (7 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Non-Hodgkin Lymphoma?

PlainTrial tracks 105 US clinical trials for Non-Hodgkin Lymphoma, of which 58 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Non-Hodgkin Lymphoma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.