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NCT06870760 · ClinicalTrials.gov registry record
Pre-malignant States to Hematologic Malignancies in Firefighters
A clinical trial of Multiple Myeloma and Leukemia, sponsored by Wake Forest University Health Sciences.
- Recruiting
- Registry status
- 300
- Enrollment target
- 1
- Study location
NCT06870760: Recruiting study of Multiple Myeloma and Leukemia, sponsored by Wake Forest University Health Sciences.
NCT06870760 is a study of Multiple Myeloma and Leukemia that is actively recruiting participants, run by Wake Forest University Health Sciences. The registered enrollment target is 300 participants, below the 546-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (45% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06870760, a study of Multiple Myeloma and Leukemia, is actively recruiting participants, sponsored by Wake Forest University Health Sciences.
- RECRUITING
- Registry status
- 300 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of the study is to evaluate if firefighter exposure to hazardous compounds will increase the incidence of premalignant hematological states which subsequently increases the risk of the development of hematologic malignancies, and potentially other pathophysiological consequences.
Primary Outcome
The presence of positive somatic mutation will be determined for each enrolled participant as a binary variable indicating if the participant is harboring clonal hematopoiesis.
Conditions Studied
Interventions
- OTHER Monoclonal Gammopathy
- OTHER Complete Blood Count with differential (CBC w/ diff)
- OTHER Clonal hematopoiesis (CHIP)
Study Locations (1)
North Carolina
- Levine Cancer Institute - Charlotte
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 300 participants |
| Start Date | 2026-03 |
| Est. Completion | 2027-04 |
What NCT06870760 shows while recruiting
NCT06870760 is an observational study that tracks outcomes without assigning an intervention. The registered 300 participants enrollment target is mid-sized for trials with a published cap, below the 546-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (45% lower).
The record links to 6 conditions, with Multiple Myeloma appearing as the primary indexed condition, and to 3 interventions - of which Monoclonal Gammopathy is the first listed.
NCT06870760 reports a single indexed study location in North Carolina.
Frequently Asked Questions
What is clinical trial NCT06870760 about?
NCT06870760 is a clinical study titled "Pre-malignant States to Hematologic Malignancies in Firefighters". The purpose of the study is to evaluate if firefighter exposure to hazardous compounds will increase the incidence of premalignant hematological states which subsequently increases the risk of the development of hematologic malignancies, and potentially other pathophysiological consequences.
What is the current status of trial NCT06870760?
This trial is currently recruiting. The enrollment target is 300 participants. The study started on 2026-03. Estimated completion is 2027-04.
What conditions does trial NCT06870760 study?
This clinical trial studies the following conditions: Multiple Myeloma, Leukemia, Non-Hodgkin Lymphoma, Plasma Cell Disorder, Monoclonal Gammopathy.
What interventions are being tested in trial NCT06870760?
The interventions under investigation include: Monoclonal Gammopathy (OTHER), Complete Blood Count with differential (CBC w/ diff) (OTHER), Clonal hematopoiesis (CHIP) (OTHER).
Who is sponsoring clinical trial NCT06870760?
This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06870760 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Multiple Myeloma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06870760's enrollment target sits among peer trials
300 75th of 438 higher than 361 of 438 other Multiple Myeloma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Multiple Myeloma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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