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NCT05253495 · ClinicalTrials.gov registry record · Phase 2

Chemoradiotherapy With Targeted Immunotherapy in Pediatric Lymphoma

A Phase 2 study of Non-Hodgkin Lymphoma and Hodgkin Lymphoma, sponsored by New York Medical College.

Recruiting
Registry status
Phase 2
Development phase
80
Enrollment target
3
Study locations

NCT05253495 is a Phase 2 study of Non-Hodgkin Lymphoma and Hodgkin Lymphoma that is actively recruiting participants, run by New York Medical College. The registered enrollment target is 80 participants, below the 151-participant average among 104 other Non-Hodgkin Lymphoma trials with a reported enrollment target (47% lower). The trial reports 3 study locations across 3 states.

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The verdict

NCT05253495, a Phase 2 study of Non-Hodgkin Lymphoma and Hodgkin Lymphoma, is actively recruiting participants, sponsored by New York Medical College.

RECRUITING
Registry status
Phase 2
Development phase
80 participants
Enrollment target
3
Study locations

Study Summary

The addition of targeted immunotherapy will be safe and well tolerated and facilitate the reduction of anthracycline exposure while preserving lymphoma disease control in children, adolescents and young adults (CAYA) with mature B-cell non-Hodgkin lymphoma (MB-NHL) and classical Hodgkin lymphoma (cHL).

Interventions

  • DRUG DOC Group B
  • DRUG Pv-COMRAD 1 and 2 Group B
  • DRUG Pv-R-CYM 1 and 2 Group B
  • DRUG DOC Group C
  • DRUG MAD CPR 1 and 2

Study Locations (3)

Alabama

  • University of Alabama - Birmingham

Florida

  • University of Flordia - Gainsville

New York

  • New York Medical College - Vallhala

Trial Details

FieldValue
Enrollment Target 80 participants
Start Date 2022-02-01
Est. Completion 2028-06-30
Phase Phase 2

Sponsor

New York Medical College

47 total trials

What the Registry Record Tells You About NCT05253495

The ClinicalTrials.gov registry entry for NCT05253495 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 80 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 151-participant average among 104 other Non-Hodgkin Lymphoma trials with a reported enrollment target (47% lower). The listed sponsor is New York Medical College, which has 47 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Non-Hodgkin Lymphoma appearing as the primary indexed condition, and to 5 interventions - of which DOC Group B is the first listed.

NCT05253495 reports 3 study locations spanning 3 distinct geographic areas - top geographies include Alabama, Florida, New York.

Frequently Asked Questions

What is clinical trial NCT05253495 about?

NCT05253495 is a clinical study titled "Chemoradiotherapy With Targeted Immunotherapy in Pediatric Lymphoma". The addition of targeted immunotherapy will be safe and well tolerated and facilitate the reduction of anthracycline exposure while preserving lymphoma disease control in children, adolescents and young adults (CAYA) with mature B-cell non-Hodgkin lymphoma (MB-NHL) and classical Hodgkin lymphoma (cH...

What is the current status of trial NCT05253495?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 80 participants. The study started on 2022-02-01. Estimated completion is 2028-06-30.

What conditions does trial NCT05253495 study?

This clinical trial studies the following conditions: Non-Hodgkin Lymphoma, Hodgkin Lymphoma.

What interventions are being tested in trial NCT05253495?

The interventions under investigation include: DOC Group B (DRUG), Pv-COMRAD 1 and 2 Group B (DRUG), Pv-R-CYM 1 and 2 Group B (DRUG), DOC Group C (DRUG), MAD CPR 1 and 2 (DRUG).

Who is sponsoring clinical trial NCT05253495?

This trial is sponsored by New York Medical College, which has 47 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05253495 being conducted?

This trial has 3 study locations across Alabama, Florida, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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