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Safety and Preliminary Efficacy of MT-601 in Patients With Relapsed/Refractory Lymphoma
NCT05798897 · View on ClinicalTrials.gov ↗
Study Summary
This study is a Phase 1 multicenter study with a Dose Escalation and Dose Expansion evaluating safety and efficacy of MT-601 administration to patients with Relapsed or Refractory Lymphoma. The starting dose administered is 200 x 10\^6 cells (flat dosing).
Conditions Studied
Interventions
- DRUG MT-601
Study Locations (7)
Colorado
- University of Colorado — Aurora
- Colorado Blood Cancer Institute (Sarah Cannon) — Denver
California
- City of Hope — Duarte
Kansas
- University of Kansas Medical Center — Kansas City
New York
- Cornell — New York
Texas
- Sarah Cannon Research Institute at St. David's South Austin — Austin
Wisconsin
- University of Wisconsin Carbone Cancer Center — Madison
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 79 participants |
| Start Date | 2023-01-02 |
| Est. Completion | 2028-02-28 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05798897
The ClinicalTrials.gov registry entry for NCT05798897 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 79 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Marker Therapeutics, which has 30 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 7 conditions, with Hodgkin Lymphoma appearing as the primary indexed condition, and to 1 intervention — of which MT-601 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05798897 reports 7 study locations spanning 6 distinct geographic areas — top geographies include Colorado, California, Kansas. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05798897 about?
NCT05798897 is a clinical study titled "Safety and Preliminary Efficacy of MT-601 in Patients With Relapsed/Refractory Lymphoma". This study is a Phase 1 multicenter study with a Dose Escalation and Dose Expansion evaluating safety and efficacy of MT-601 administration to patients with Relapsed or Refractory Lymphoma. The starting dose administered is 200 x 10\^6 cells (flat dosing).
What is the current status of trial NCT05798897?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 79 participants. The study started on 2023-01-02. Estimated completion is 2028-02-28.
What conditions does trial NCT05798897 study?
This clinical trial studies the following conditions: Hodgkin Lymphoma, Non Hodgkin Lymphoma, Hodgkin Lymphoma, Adult, Non-Hodgkin Lymphoma, Adult, Non-Hodgkin Lymphoma, Refractory. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05798897?
The interventions under investigation include: MT-601 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05798897?
This trial is sponsored by Marker Therapeutics, which has 30 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05798897 being conducted?
This trial has 7 study locations across California, Colorado, Kansas, New York, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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