Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 58 recruiting now early-phase tilt #120 of 28,707 conditions

Non-Hodgkin Lymphoma: early-phase trial registry

58 of 107 indexed Non-Hodgkin Lymphoma trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #120 of 28,707 conditions by registered trial count.

107 US clinical trials · 58 currently recruiting · #120 of 28,707 conditions by registered trial count

Non-Hodgkin Lymphoma: 107 US clinical trials tracked, 58 recruiting.

Non-Hodgkin Lymphoma is the subject of 107 registered US clinical trials on ClinicalTrials.gov, 58 of them currently open to new participants. 6 are in Phase 3-4 (later-stage) and 86 in Phase 1-2 (earlier-stage). The most active sponsor is Baylor College of Medicine, running 7 of these trials.

Enrollment posture brief

Registry condition non-hodgkin-lymphoma

OPEN 58 | RECR 54% | LATE 6 | EARLY 86 | RANK #120 | SPON 7

Nearest open-share peer: Bulimia Nervosa (54% recruiting · 24 trials)

Breast Carcinoma58.9%Non-Hodgkin Lymphoma (this)54%Cognitive Impairment43.4%Crohn's Disease34.9%Hepatitis C12%
Open-enrollment share among volume-matched conditions near Non-Hodgkin Lymphoma

Non-Hodgkin Lymphoma lists 58 open slots (54% of 107 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Non-Hodgkin Lymphoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Non-Hodgkin Lymphoma is recruiting above its size-band peers.

    58 of 107 indexed trials (54.2%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Non-Hodgkin Lymphoma trials is spread across many organizations.

    Baylor College of Medicine accounts for 7 of 107 trials (6.5%). 77 distinct sponsors appear on at least one study for this condition label.

  3. Most Non-Hodgkin Lymphoma trials plan to enrol fewer than 100 people.

    Median target enrolment is 54 among the 107 trials that report a genuine target (sentinel values excluded). 68 of those (63.6%) plan for fewer than 100 participants.

  4. Non-Hodgkin Lymphoma research is mostly interventional.

    98 interventional and 9 observational studies make up this index (91.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 167Phase 219Phase 34Phase 42

Open and recent trials

107 total, page 1 of 3

RECRUITING 2,000 participants

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

Wake Forest University Health Sciences

NCT06418204

RECRUITING 2,000 participants

Evaluating the Impact of Social and Genetic Factors on Outcomes in Adolescent and Young Adult Cancer Survivors

ECOG-ACRIN Cancer Research Group

NCT06002828

RECRUITING Phase 4 787 participants

A Master Protocol to Evaluate the Long-Term Safety of (LY3527727) Pirtobrutinib

Eli Lilly and Company

NCT06876649

RECRUITING Phase 1 614 participants

A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies

BeOne Medicines

NCT05006716

RECRUITING Phase 2 496 participants

A Study to Evaluate Adverse Events and Change in Disease Activity of Subcutaneous (SC) Epcoritamab in Combination With Oral and Intravenous Anti-Neoplastic Agents in Adult Participants With Non-Hodgkin Lymphoma

Genmab

NCT05283720

RECRUITING Phase 3 400 participants

A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy

Lyell Immunopharma

NCT07188558

RECRUITING Phase 3 386 participants

A Study to Evaluate Efficacy, Safety, and PK of XEMBIFY®+Standard Medical Treatment (SMT) Compared to Placebo+SMT to Prevent Infections in Participants With HGG and Recurrent or Severe Infections Associated With B-cell Chronic Lymphocytic Leukemia, Multiple Myeloma, and Non-Hodgkin Lymphoma

Grifols Therapeutics

NCT05645107

RECRUITING 300 participants

Pre-malignant States to Hematologic Malignancies in Firefighters

Wake Forest University Health Sciences

NCT06870760

RECRUITING Phase 4 279 participants

A Study of (LY3527727) Pirtobrutinib in Participants With Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma or Non-Hodgkin Lymphoma

Eli Lilly and Company

NCT06876662

RECRUITING Phase 1 270 participants

Study of LYL314 in Aggressive Large B-Cell Lymphoma

Lyell Immunopharma

NCT05826535

RECRUITING Phase 1 250 participants

Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies

CellCentric

NCT04068597

RECRUITING Phase 2 216 participants

CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors for the Prevention of CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplant

City of Hope Medical Center

NCT06059391

RECRUITING Phase 1 184 participants

Phase1/2 Study of IPH6501 in Patients With Relapsed /Refractory B-Cell Non-Hodgkin Lymphoma

Innate Pharma

NCT06088654

RECRUITING Phase 1 155 participants

Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (ViPOR) in Relapsed/Refractory B-cell Lymphoma

National Cancer Institute (NCI)

NCT03223610

RECRUITING Phase 2 150 participants

Auto Stem Cell Transplant for Lymphoma Patients

Masonic Cancer Center, University of Minnesota

NCT03125642

RECRUITING 150 participants

Lentiviral Gene Therapy (Zamtocabtagene Autoleucel) LTFU

Miltenyi Biomedicine

NCT06116110

RECRUITING NA 140 participants

Lifestyle Intervention of Food and Exercise for Lymphoma Survivors

University of Miami

NCT05839210

RECRUITING Phase 1 135 participants

Dose-escalation and Dose-expansion Study of Safety of Azer-cel (PBCAR0191) in Participants With Relapsed/Refractory (r/r) Non-Hodgkin Lymphoma (NHL) and r/r B-cell Acute Lymphoblastic Leukemia (B-ALL)

Imugene Limited

NCT03666000

RECRUITING Phase 1 121 participants

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab or Glofitamab in Combination With CC-220 and/or CC-99282 in Participants With B-Cell Non-Hodgkin Lymphoma

Hoffmann-La Roche

NCT05169515

RECRUITING Phase 1 120 participants

A Safety and Efficacy Study Evaluating CTX112 in Subjects With Relapsed or Refractory B-Cell Malignancies

CRISPR Therapeutics

NCT05643742

RECRUITING Phase 1 120 participants

AS-1763 in Patients With Previously Treated CLL/SLL or Non-Hodgkin Lymphoma

Carna Biosciences

NCT05602363

RECRUITING NA 110 participants

Improving Exercise Capacity With a Tailored Physical Activity Intervention

Wake Forest University Health Sciences

NCT05595577

RECRUITING Phase 2 100 participants

Mozobil for Autologous Hematopoietic Stem Cell Transplantation

Thomas Jefferson University

NCT07188090

RECRUITING Phase 1 100 participants

Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

Newave Pharmaceutical

NCT04771572

RECRUITING Phase 1 98 participants

Study of SGR-1505 in Mature B-Cell Neoplasms

Schrödinger

NCT05544019

RECRUITING Phase 1 90 participants

Constitutive IL7R (C7R) Modified Banked Allogeneic CD30.CAR EBVSTS for CD30-Positive Lymphomas

Baylor College of Medicine

NCT06176690

RECRUITING Phase 2 80 participants

Chemoradiotherapy With Targeted Immunotherapy in Pediatric Lymphoma

New York Medical College

NCT05253495

RECRUITING Phase 1 79 participants

Safety and Preliminary Efficacy of MT-601 in Patients With Relapsed/Refractory Lymphoma

Marker Therapeutics

NCT05798897

RECRUITING Phase 1 72 participants

CRISPR-Edited Allogeneic Anti-CD19 CAR-T Cell Therapy for Relapsed/Refractory B Cell Non-Hodgkin Lymphoma (ANTLER)

Caribou Biosciences

NCT04637763

RECRUITING Phase 1 68 participants

Preliminary Safety and Tolerability of CD19x22 CAR T Cells in Adolescent and Adult R/R B-NHL Patients

University of Colorado, Denver

NCT05098613

RECRUITING Phase 1 64 participants

Activated T-Cells Expressing 2nd or 3rd Generation CD19-Specific CAR, Advanced B-Cell NHL, ALL, and CLL (SAGAN)

Baylor College of Medicine

NCT01853631

RECRUITING Phase 1 60 participants

CD30 CAR T Cells, Relapsed CD30 Expressing Lymphoma (RELY-30)

Baylor College of Medicine

NCT02917083

RECRUITING Phase 1 55 participants

Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid in Combination With Polatuzumab (ViPOR-P) in Relapsed/Refractory B-cell Lymphoma

National Cancer Institute (NCI)

NCT04739813

RECRUITING Phase 2 54 participants

Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Diseases

Fred Hutchinson Cancer Center

NCT06013423

RECRUITING Phase 2 53 participants

Amping up With PemJAK

Seda S. Tolu

NCT07283822

RECRUITING 50 participants

Transgene Assay Testing Service of Tumor Samples From Patients Who Received a Bristol-Myers Squibb Manufactured Gene Modified Cell Therapy and Have a Qualifying Second Primary Malignancy

Bristol-Myers Squibb

NCT06357754

RECRUITING Phase 2 49 participants

A Study of Carmustine With and Without Ethanol in Subjects With Lymphoma

VIVUS

NCT06915246

RECRUITING Phase 1 48 participants

SB-4826 in Adult Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin Lymphomas

University of California, San Diego

NCT07222631

RECRUITING Phase 2 45 participants

Epco, Zanu, Ritux for R/R FL or MZL

Reid Merryman, MD

NCT06563596

RECRUITING Phase 1 42 participants

ACE1831 in Adult Subjects With Relapsed/ Refractory CD20-expressing B-cell Malignancies

Acepodia Biotech

NCT05653271

RECRUITING Phase 2 39 participants

Isatuximab During Stem Cell Collection and Transplant in Patients With Multiple Myeloma and Lymphoma

Divaya Bhutani

NCT05346809

RECRUITING Phase 1 36 participants

Anti-CD19 Chimeric Antigen Receptor T Cells for Treatment of Relapsed or Refractory Non-Hodgkin Lymphoma

C. Babis Andreadis

NCT04545762

RECRUITING Phase 1 32 participants

PET Imaging Study of 64Cu-GRIP B for Patients Receiving CD19-directed CAR-T Therapy

Michael Randall

NCT06522932

RECRUITING Early Phase 1 30 participants

In-Human CXCR4 Imaging of Hematologic and Solid Tumors Using [68Ga]-Pentixafor-PET

Memorial Sloan Kettering Cancer Center

NCT05093335

RECRUITING Phase 2 30 participants

Phase II Study of Pirtobrutinib With Venetoclax In Relapsed-Refractory MCL (Mantle Cell Lymphoma) Patients

M.D. Anderson Cancer Center

NCT05529069

RECRUITING Phase 1 30 participants

Study of IOMAB-ACT Followed by CAR-T Cell Therapy for Patients Relapsed or Refractory (Diffuse Large B-cell Lymphoma

University of Texas Southwestern Medical Center

NCT06768905

RECRUITING Phase 2 25 participants

Obinutuzumab and ICE Chemotherapy in Refractory/Recurrent CD20+ Mature NHL

New York Medical College

NCT02393157

RECRUITING Phase 1 25 participants

Pomalidomide and Dose-Adjusted EPOCH +/- Rituximab for HIV-Associated Lymphomas

National Cancer Institute (NCI)

NCT05389423

RECRUITING Phase 1 24 participants

CD79b-19 CAR T Cells in Non-Hodgkin Lymphoma

Marcela V. Maus, M.D.,Ph.D.

NCT06026319

RECRUITING Phase 1 24 participants

TmCD19-IL18 in CD19+ Cancers

University of Pennsylvania

NCT05989204

Page 1 of 3 Next →

Phase Distribution

PhaseTrial count
Phase 1 67
Phase 2 19
Phase 3 4
Phase 4 2

Named interventions

Most-linked intervention names on Non-Hodgkin Lymphoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Cyclophosphamide Drug
16 trials
Fludarabine Drug
12 trials
Rituximab Drug
6 trials
Pirtobrutinib Drug
4 trials
Epcoritamab Drug
4 trials
Biospecimen Collection Procedure
4 trials
Venetoclax Drug
4 trials
Tocilizumab Drug
3 trials

US sites by state

Facility locations filed on Non-Hodgkin Lymphoma trials. A trial with sites in several states counts in each.

Texas 33 trials
California 31 trials
New York 30 trials
Ohio 21 trials
Florida 19 trials
Georgia 17 trials
Massachusetts 16 trials
Pennsylvania 15 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Non-Hodgkin Lymphoma page

107 registered trials, 58 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Non-Hodgkin Lymphoma condition card totals 107 registered trials; most-linked intervention Cyclophosphamide; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.